How hepatitis D virus can hinder the control of hepatitis B virus. [PDF]
PLoS ONE, 2009 BACKGROUND: Hepatitis D (or hepatitis delta) virus is a defective virus that relies on hepatitis B virus (HBV) for transmission; infection with hepatitis D can occur only as coinfection with HBV or superinfection of an existing HBV infection.
Maria Xiridou +3 more
doaj +1 more source
Altered gut microbiota is associated with the formation of occult hepatitis B virus infection
Microbiology SpectrumHepatitis B virus (HBV), a common blood transmission pathogen worldwide, can lead to viral hepatitis, cirrhosis, liver cancer, and other liver diseases.
Bochao Liu +11 more
doaj +1 more source
Upregulation of the Tim-3/galectin-9 pathway of T cell exhaustion in chronic hepatitis B virus infection. [PDF]
, 2012 The S-type lectin galectin-9 binds to the negative regulatory molecule Tim-3 on T cells and induces their apoptotic deletion or functional inactivation.
Cheng, Y +59 more
core +1 more source
Vaccines, 2021 Chronic hepatitis B affects more than 250 million individuals worldwide, putting them at risk of developing liver cirrhosis and liver cancer. While antiviral immune responses are key to eliminating hepatitis B virus (HBV) infections, insufficient ...
Percy A. Knolle +4 more
doaj +1 more source
Host genetic factors in hepatitis B infection, liver cancer and vaccination response: a review with a focus on Africa. [PDF]
, 2012 The disease burden due to hepatitis B virus (HBV) infection remains significant; 350 million people are infected world-wide, and around half a million deaths each year are due to HBV-related liver disease and hepatocellular carcinoma (HCC).
Hall, Andrew J +3 more
core +1 more source
Medicina, 2021 Background and Objectives: Hepatitis B virus infection remains a major public health concern. The interaction between hepatitis B virus (HBV) hepatitis B virus and the host inflammatory response is an important contributing factor driving liver damage ...
Alice Elena Ghenea +12 more
doaj +1 more source
Modulation of the CD8+-T-cell response by CD4+ CD25+ regulatory T cells in patients with Hepatitis B virus infection [PDF]
, 2005 CD4+ CD25+ regulatory T cells have been shown to maintain peripheral tolerance against self and foreign antigens. In this study we analyzed the effect of circulating CD4+ CD25+ T cells on CD8+-T-cell responses of patients with chronic and resolved ...
Gotto, J +19 more
core +1 more source
Changes in viral load and HBsAg and HBeAg status with age in HBV chronic carriers in The Gambia. [PDF]
, 2008 BACKGROUND: Little is known about changes in hepatitis B viral load (HBV DNA) in relation to age in Africa. The aim of this study is to determine the natural course of HBV chronic infection, particularly in relation to sequential changes in serum HBV DNA
Jeffries, David +31 more
core +1 more source
Anti-Hepatitis B Virus Activity of Esculetin from Microsorium fortunei In Vitro and In Vivo
Molecules, 2019 Coumarins are widely present in a variety of plants and have a variety of pharmacological activities. In this study, we isolated a coumarin compound from Microsorium fortunei (Moore) Ching; the compound was identified as esculetin by hydrogen and carbon ...
Si-Xin Huang +9 more
doaj +1 more source
Antiviral Treatment of Chronic Hepatitis B Virus (HBV) Infections [PDF]
Viruses, 2010 While 25 compounds have been formally licensed for the treatment of HIV infection (AIDS), only seven licensed products are currently available for the treatment of chronic hepatitis B virus (HBV) infection: interferon-α, pegylated interferon-α, lamivudine, adefovir (dipivoxil), entecavir, telbivudine and tenofovir (disoproxil fumarate).
Clercq, De, Férir, Kaptein, Neyts
openaire +3 more sources