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Hepatitis C Vaccines, Antibodies, and T Cells [PDF]
Frontiers in Immunology, 2018 The development of vaccines that protect against persistent hepatitis C virus (HCV) infection remain a public health priority. The broad use of highly effective direct-acting antivirals (DAAs) is unlikely to achieve HCV elimination without vaccines that ...
Naglaa H. Shoukry, Naglaa H. Shoukry
doaj +3 more sources
Antibody Responses in Hepatitis C Infection [PDF]
Cold Spring Harbor Perspectives in Medicine, 2020 Antibody responses in hepatitis C virus (HCV) have been a rather mysterious research topic for many investigators working in the field. Chronic HCV infection is often associated with dysregulation of immune functions particularly in B cells, leading to abnormal lymphoproliferation or the production of autoantibodies that exacerbate inflammation and ...
openaire +2 more sources
Memorias do Instituto Oswaldo Cruz, 2006 In this report, we examine the adaptability of commercially available serological kits to detect antibodies markers for viral hepatitis in oral fluid samples. We also assessed the prevalence of hepatitis A, B, and C virus-specific antibodies, and related
Luciane A Amado +4 more
doaj +1 more source
Seroprevalence of hepatitis B and C among domestic and healthcare waste handlers in Belo Horizonte, Brazil. [PDF]
, 2016 Infection with the hepatitis B and C viruses may occur through contact with infected body fluids, including injury with infected sharps. Collectors of domestic or healthcare wastes are potentially exposed to these infections.
Cairncross, Sandy +6 more
core +1 more source
Prevalence of hepatitis C virus infection in patients with cardiomyopathy
Annals of Hepatology, 2009 Chronic hepatitis C can be associated with extrahepatic manifestations; thus, we explored the association of this viral infection with dilated cardiomyopathy in a group of sixty-three patients with a cardiac ejection fraction of less than 40% determined ...
Vijaya Boyella; +5 more
doaj +1 more source
Hepatoma cell density promotes claudin-1 and scavenger receptor BI expression and hepatitis C virus internalization. [PDF]
, 2009 Hepatitis C virus (HCV) entry occurs via a pH- and clathrin-dependent endocytic pathway and requires a number of cellular factors, including CD81, the tight-junction proteins claudin 1 (CLDN1) and occludin, and scavenger receptor class B member I (SR-BI).
Balfe, Peter +5 more
core +2 more sources
Adverse reactions of biological therapies in patients with psoriasis [PDF]
, 2017 Psoriasis is a chronic, immune-mediated disorder characterized by well demarcated, erythematous plaques covered by thick, silvery-white scales, most often located on the knees, elbows, sacral area and scalp.
Georgescu, Simona R. +5 more
core +4 more sources
Hepatitis C Virus Antibodies and Vitiligo Disease [PDF]
Iranian Journal of Public Health, 2005 Vitiligo is a common skin disorder, characterized by depigmented patches due to selective destruction of melanocytes. The etiology of this disease is unknown. A number of hypotheses including viral theory have been proposed to explain the etiology.
Z Jadali +6 more
doaj +2 more sources
Identification of hepatitis a virus mimotopes by phage display, antigenicity and immunogenicity [PDF]
, 2007 A phage-displayed peptide approach was used to identify ligands mimicking antigenic determinants of hepatitis A virus (HAV) for the first time. Bacteriophages displaying HAV mimotopes were isolated from a phage-display peptide library by affinity ...
Alicia Aguilar +54 more
core +1 more source
Journal of Medical Case Reports, 2009 Introduction Pure red cell aplasia due to anti-epoetin antibodies is a known complication of epoetin therapy for anemia due to chronic kidney disease. This disease has not previously been well described in the setting of therapy for chronic hepatitis C ...
Behler Caroline M +3 more
doaj +1 more source