Results 111 to 120 of about 1,173,658 (399)

The prevalence of hepatitis C virus infection in Egypt 2015: implications for future policy on prevention and treatment

open access: yesLiver international (Print), 2016
In 2015, a national Egyptian health issue survey was conducted to describe the prevalence of hepatitis C virus (HCV) infection. In this paper, we describe the HCV burden in 2015, compare the results with the national survey conducted in 2008, and discuss
A. Kandeel   +5 more
semanticscholar   +1 more source

Lactylated SPTAN1 Accelerates Hepatocellular Carcinoma Progression by Promoting NOTCH1/HES1 Activation and Immunosuppression

open access: yesAdvanced Science, EarlyView.
This study identifies SPTAN1‐kla as a novel oncogenic driver in HBV‐driven HCC, linking metabolic, epigenetic, and immune mechanisms. SPTAN1‐kla promotes HCC progression via NOTCH1/HES1 activation and immunosuppression. Findings highlight that targeting SPTAN1‐kla provides a framework for HCC treatment to improve clinical outcomes in HBV infected ...
Zengbin Wang   +8 more
wiley   +1 more source

Bioinformatics Techniques used in Hepatitis C Virus Research

open access: yesJournal of Pure and Applied Microbiology, 2017
Hepatitis C is widely spread and induces life threatening situations. Researchers from various fields have developed vaccine, but they are not that effective because of the variation in genotype of Hepatitis virus and also not much affordable.
Vikas Kaushik   +2 more
doaj   +1 more source

Incidence, prevalence, and clinical course of hepatitis C following liver transplantation [PDF]

open access: yes, 1992
Hepatitis C virus (HCV) is the agent responsible for posttransfusion hepatitis. The incidence, timing, and clinical course of HCV positive hepatitis in liver transplant recipients are unknown.
A.Jake Demetris   +35 more
core   +1 more source

Hepatitis C virus infection in children and adolescents

open access: yesHepatology Communications, 2017
Hepatitis C virus (HCV) infection remains a major public health burden, with an estimated worldwide prevalence of 2.5% of the population (177.5 million infected adults); this ranges from 1.3% in the Americas to 2.9% in Africa.1 In the United States alone,
J. Squires, W. Balistreri
semanticscholar   +1 more source

Procyanidin Capsules Combat ALF by Restoring Mitochondrial Homeostasis and Inhibiting Necroptosis via the PGAM5/DRP1/PINK1 Pathway

open access: yesAdvanced Science, EarlyView.
A biomimetic self‐assembly strategy, Procyanidin Capsules (PC‐Ca), has been developed, which has great stability, bioavailability, and liver‐targeting efficacy and modulates the KEAP1‐NRF2 axis to inhibit ROS formation and necroptosis, regulate mitochondrial homeostasis through the PGAM5/DRP1/PINK1 signaling pathway in thioacetamide (TAA)‐induced ALF ...
Qing Shi   +8 more
wiley   +1 more source

Acute polymyositis during treatment of acute hepatitis C with pegylated interferon alpha-2b [PDF]

open access: yes, 2005
Hepatitis C virus is not cleared after primary infection in 50-85% of subjects exposed to hepatitis C virus. Anti-viral treatment during the early phase of infection significantly enhances the likelihood of a sustained clearance of hepatitis C virus ...
Almasio, P.   +4 more
core   +1 more source

Hepatitis C Virus NS5A Protein Triggers Oxidative Stress by Inducing NADPH Oxidases 1 and 4 and Cytochrome P450 2E1

open access: yesOxidative Medicine and Cellular Longevity, 2016
Replication of hepatitis C virus (HCV) is associated with the induction of oxidative stress, which is thought to play a major role in various liver pathologies associated with chronic hepatitis C.
O. Smirnova   +6 more
semanticscholar   +1 more source

VIROLOGY OF HEPATITIS C VIRUS

open access: yesClinics in Liver Disease, 1997
Advances in molecular biology techniques have allowed the cloning of HCV and the characterization of this virus. This article provides a short summary of our current knowledge on the genomic organization of HCV, the implications of its genetic heterogeneous nature, and the probable replication strategy of this virus.
Departments of Medicine (VC, JF, JL) ( host institution )   +3 more
openaire   +3 more sources

B‐EPIC: A Transformer‐Based Language Model for Decoding B Cell Immunodominance Patterns

open access: yesAdvanced Science, EarlyView.
B‐Epic: Achieving high‐accuracy B cell epitope prediction through Transformer architecture. Comprehensive validation demonstrates B‐Epic's robust performance across diverse datasets. B‐Epic facilitates vaccine development for H. pylori and EBV, addressing critical public health challenges.
Jun‐Ze Liang   +16 more
wiley   +1 more source

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