Results 261 to 270 of about 1,173,658 (399)

Impact of Hepatitis C Virus Clearance on Cardiovascular Risk: A Real-World Experience From the Nationwide Taiwan Hepatitis C Virus Registry. [PDF]

Kaohsiung J Med Sci
Hu PJ, Tsai PC, Chen CY, Kuo HT, Hung CH, Tseng KC, Lai HC, Peng CY, Wang JH, Chen JJ, Lee PL, Chien RN, Yang CC, Lo GH, Kao JH, Liu CJ, Liu CH, Yan SL, Lin CY, Su WW, Chu CH, Chen CJ, Tung SY, Tai CM, Lin CW, Lo CC, Cheng PN, Chiu YC, Wang CC, Cheng JS, Tsai WL, Lin HC, Huang YH, Yeh ML, Huang CF, Hsieh MH, Huang JF, Dai CY, Chung WL, Wang YH, Yu ML, Bair MJ, T‐COACH Study Group.   +42 more
europepmc   +1 more source

Gut Dysbiosis Associated With Hepatitis C Virus Infection

Clinical Infectious Diseases, 2018
Takako Inoue, J. Nakayama, K. Moriya, H. Kawaratani, Rie Momoda, Kiyoaki Ito, Etsuko Iio, S. Nojiri, Kei Fujiwara, M. Yoneda, H. Yoshiji, Yasuhito Tanaka   +11 more
semanticscholar   +1 more source

Effects of High‐ and Low‐Fat Meals on the Bioavailability and Pharmacokinetics of Votoplam, a HTT Gene Splicing Modifier

Clinical Pharmacology in Drug Development, EarlyView.
Abstract Votoplam is a novel, orally bioavailable, small molecule HTT gene splicing modifier that is being developed for the treatment of Huntington's disease. This was a single dose, open‐label, two‐period, crossover food effect study that evaluated the effect of high‐ and low‐fat meals on 20 mg votoplam in healthy participants. There was a washout of
Lucy Lee, Amy‐Lee Richards, Nageswara Reddy, Brian Beers, Lee Golden, Ronald Kong   +5 more
wiley   +1 more source

Assessment of hepatitis C virus permissiveness in iteratively genetically humanized mice. [PDF]

J Virol
Schwoerer MP, Carver S, Cafiero TR, Joyce B, Berggren KA, Suzuki S, Heller B, O'Connell AK, Gertje HP, Crossland NA, Posfai E, Ploss A.   +11 more
europepmc   +1 more source

Therapeutic Silencing of MicroRNA-122 in Primates with Chronic Hepatitis C Virus Infection

Science, 2010
R. Lanford, E. S. Hildebrandt-Eriksen, A. Petri, R. Persson, M. Lindow, M. E. Munk, S. Kauppinen, H. Ørum   +7 more
semanticscholar   +1 more source

Drug Repositioning of Pegbing® for Essential Thrombocythemia: Insights from PK/PD Modeling and Extrapolation

Clinical Pharmacology &Therapeutics, EarlyView.
Pegbing® (peginterferon alfa‐2b), a pegylated interferon‐alpha, is approved for the treatment of chronic hepatitis B (CHB) and C. One of its adverse effects is platelet (PLT) suppression. It is currently being repurposed for the treatment of essential thrombocythemia (ET), a rare myeloproliferative disorder characterized by abnormally elevated PLT ...
Weizhe Jian, Yalin Yin, Rong Chen, Junsheng Xue, Jianbo Gu, Zhengfang Du, Ruoyi He, Tianyan Zhou   +7 more
wiley   +1 more source

Effect of Hepatitis C Virus Genotype, Cirrhosis, and Viral Cure on Serum Phosphatidylinositol Species Profiles. [PDF]

Biomedicines
Weigand K, Peschel G, Höring M, Krautbauer S, Liebisch G, Müller M, Buechler C.   +6 more
europepmc   +1 more source

Natural evolution of hepatitis C virus infection in hemodialysis Tunisian patients and CTLA-4 SNP's

, 2015
Leila Ksiaa Cheikhrouhou, Yousr Lakhoua-Gorgi, Imen Sfar, Salwa Jendoubi-Ayed, Houda Aouadi, Mouna Makhlouf, K. Ayed, T. Ben Abdallah   +7 more
openalex   +2 more sources

Expression of mutant TIE2 p.L914F during mouse development causes embryonic lethality and defects in vascular remodeling

Developmental Dynamics, EarlyView.
Abstract Background Sporadic venous malformation (VM) is associated with the hyperactivating p.L914F mutation in TIE2, a receptor tyrosine kinase essential for vascular development. This mutation is not found in hereditary VM, suggesting incompatibility with life when expressed during early vascular development.
Lindsay J. Bischoff, Sandra Schrenk, Kara Soroko, Chhiring Sherpa, Ashok Arasu, Damien Reynaud, Elisa Boscolo   +6 more
wiley   +1 more source

Trends in Use of Direct-Acting Antivirals for Treatment of Hepatitis C Virus Infection in Australia 2016-2024. [PDF]

J Viral Hepat
Luong CL, Ellett LK, Pratt N, Staff K, Janetzki J.   +4 more
europepmc   +1 more source