Results 91 to 100 of about 19,491,478 (363)

Tryptophan Metabolite Indole‐3‐Aldehyde Induces AhR and c‐MYC Degradation to Promote Tumor Immunogenicity

open access: yesAdvanced Science, EarlyView.
Tryptophan metabolite Indole‐3‐aldehyde (I3A) downregulates cytosolic AhR and p‐ERK/c‐MYC proteins, together enhancing STAT3 phosphorylation and tumor immunogenicity. Overexpression of the Trp metabolic enzyme interleukin‐4‐induced gene‐1 (IL4I1) in tumor cells increases intracellular levels of I3A and enhances tumor immunogenicity.
Lei Cui   +19 more
wiley   +1 more source

Integrated care for methadone maintenance patients with hepatitis C virus infection

open access: yesKaohsiung Journal of Medical Sciences, 2019
The majority of patients undergoing methadone maintenance treatment (MMT) are neither examined nor treated for hepatitis C virus (HCV) infection. We aimed to evaluate an integrated referral model in the management of HCV among MMT patients.
Chi‐Ming Tai   +10 more
doaj   +1 more source

Hepatitis E and blood donation safety in selected European countries: a shift to screening?

open access: yesEuro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin, 2017
The public health implications of hepatitis E virus (HEV) in Europe have changed due to increasing numbers of hepatitis E cases and recent reports of chronic, persistent HEV infections associated with progression to cirrhosis in immunosuppressed patients.
D. Domanović   +18 more
semanticscholar   +1 more source

Development and Validation of Machine Learning‐Based Marker for Early Detection and Prognosis Stratification of Nonalcoholic Fatty Liver Disease

open access: yesAdvanced Science, EarlyView.
This study constructs a stacked multimodal machine learning model for nonalcoholic fattly liver disease (NAFLD) by integrating genetic and clinical features, and synthesize an in‐silico quantitative marker (ISNLD) that enables personalized risk stratification for intrahepatic and extrahepatic outcomes of high‐risk individuals of NAFLD.
Lushan Xiao   +14 more
wiley   +1 more source

Hepatitis E [PDF]

open access: yesBMC Infectious Diseases, 2014
Sven Pischke, Heiner Wedemeyer
openaire   +2 more sources

Hepatitis E Infection [PDF]

open access: yesBaylor University Medical Center Proceedings, 2012
Hepatitis E usually presents as a self-limiting viral hepatitis. It is not commonly seen in the United States and is more prevalent in endemic areas. Signs and symptoms are similar to those of other acute viral hepatitis infections. Here a case is presented of a man who recently returned from India and was found to have acute viral hepatitis E ...
openaire   +3 more sources

Recent knowledge on hepatitis E virus in Suidae reservoirs and transmission routes to human

open access: yesVeterinary Research, 2017
Hepatitis E virus (HEV) causes self-limiting acute hepatitis in humans that can eventually result in acute liver failures or progress to chronic infections. While in tropical and sub-tropical areas, HEV infections are associated with important waterborne
N. Pavio   +3 more
semanticscholar   +1 more source

Engineered RGD‐Treg‐Exos Targeted Delivery of miR‐218‐5p to Activate Mitophagy and Attenuate Podocyte Injury in Diabetic Kidney Disease

open access: yesAdvanced Science, EarlyView.
Tregs‐Exos deliver miR‐218‐5p to increase mitophagy in podocytes by inhibiting the TNC/TLR4/SRC/FUNDC1 pathway. RGD‐Treg‐Exos, engineered to express RGD peptides on the membrane surface, bind to integrins on the surface of podocytes and effectively target podocytes for the delivery of miR‐218‐5p, which increases mitophagy and reduces apoptosis in ...
Zhaochen Guo   +11 more
wiley   +1 more source

Hepatitis E: Current Status in India and Other Asian Countries

open access: yesJournal of Pure and Applied Microbiology, 2019
Six types of hepatitis infections are accounted for the inflammation of liver in human throughout the world and assigned the letter A, B, C, D, E and G.
Harsh Kumar, Nassim Kamar, Dinesh Kumar
doaj   +1 more source

Hepatitis E: Update on Prevention and Control

open access: yesBioMed Research International, 2018
Hepatitis E virus (HEV) is a common etiology of acute viral hepatitis worldwide. Recombinant HEV vaccines have been developed, but only one is commercially available and licensed in China since 2011.
J. Melgaço   +5 more
semanticscholar   +1 more source

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