Results 111 to 120 of about 697,291 (350)
17,β-estradiol inhibits hepatitis C virus mainly by interference with the release phase of its life cycle [PDF]
, 2016 Rationale & Aim: Estrogen and estrogen-mediated signalling protect from hepatitis C virus through incompletely understood mechanisms. We aimed to ascertain which phase(s) of HCV life cycle is/are affected by estrogens.
Barbaglia, Matteo N. +10 more
core +2 more sources
Advanced Science, EarlyView.We identify an antagonistic ubiquitin circuit that controls cellular permissiveness to multiple coronaviruses. The deubiquitinase USP7 stabilizes the epigenetic regulator KDM6A to upregulate viral receptors, while the E3 ligase RNF40 degrades KDM6A by catalyzing K6/K11‐ubiquitin chains of KDM6A for autophagic degradation.
Meng‐Zhuo Huang +9 more
wiley +1 more source
Integrated care for methadone maintenance patients with hepatitis C virus infection
Kaohsiung Journal of Medical Sciences, 2019 The majority of patients undergoing methadone maintenance treatment (MMT) are neither examined nor treated for hepatitis C virus (HCV) infection. We aimed to evaluate an integrated referral model in the management of HCV among MMT patients.
Chi‐Ming Tai +10 more
doaj +1 more source
Scientific basis of surveillance and control of hepatitis E in the temperate climate
Журнал инфектологии, 2017 Purpose of the study. Epidemiological characteristics of hepatitis E in the territory of the Central European region of Russia (on the example of the Nizhny Novgorod region) for the scientific justification of the system of epidemiological monitoring and
A. V. Polyanina +2 more
doaj +1 more source
Seroprevalence Of Hepatitis-b Virus In Mid And Far Western Region In Nepal [PDF]
, 2012 Hepatitis B is significant health problems that might involve the late sequel of liver cirrhosis and hepatocellular carcinoma. The present study aimed to know the seroprevalence of hepatitis B virus (HBV) in mid and far western region in Nepal with ...
H, S. A. (Siddiqui) +3 more
core
Interferon alfa for chronic hepatitis B infection: Increased efficacy of prolonged treatment [PDF]
, 1999 Interferon alfa (IFN-a) is the primary treatment for chronic hepatitis B. The standard duration of IFN-a therapy is considered 16 weeks; however, the optimal treatment length is still poorly defined.
Carreño, V. (Vicente) +15 more
core +4 more sources
Advanced Science, EarlyView.This study developed a novel drug delivery platform that overcomes the blood‐brain barrier in glioblastoma. By fusing IGFBP7 with small extracellular vesicles, the platform specifically targets tumor vasculature. It effectively delivers temozolomide, suppressing tumor growth at low doses.
Lingling Liu +17 more
wiley +1 more source
Mixed infections yersiniosis with acute viral hepatitis A and E
Журнал инфектологии, 2018 The article describes two clinical cases of yersiniosis accompanied by Hepatitis A and E. In patients with a clinical picture of icteric form of acute viral hepatitis, there was a symptomatic gastrointestinal form of yersiniosis. Patients were discharged
A. L. Bondarenko +4 more
doaj +1 more source
Challenge pools of hepatitis C virus genotypes 1-6 prototype strains: replication fitness and pathogenicity in chimpanzees and human liver-chimeric mouse models [PDF]
, 2010 Chimpanzees represent the only animal model for studies of the natural history of hepatitis C virus (HCV). To generate virus stocks of important HCV variants, we infected chimpanzees with HCV strains of genotypes 1-6 and determined the infectivity titer ...
Bukh, Jens +11 more
core +1 more source