Results 141 to 150 of about 641,799 (359)
Advanced Science, EarlyView.Macrophage GHSR‐Foxo1 axis regulates CCl4‐induced liver fibrosis by promoting inflammation and TGF‐β1‐mediated HSC activation. GHSR activates PKA‐dependent phosphorylation of Foxo1 at serine 273, promoting macrophage pro‐inflammatory polarization to enhance the production of pro‐inflammatory cytokines that damage hepatocytes, thereby inducing liver ...
Da Mi Kim +9 more
wiley +1 more source
The Immune Microenvironment: New Therapeutic Implications in Organ Fibrosis
Advanced Science, EarlyView.This review summarizes recent advances in understanding the immune microenvironment's role in fibrosis, focusing on phenotypic/functional alterations of immune cells and their dynamic interactions with other cellular constituents within tissues. The authors further explore therapeutic opportunities and challenges in targeting immune microenvironment ...
Xiangqi Chen +6 more
wiley +1 more source
Seroprevalence of Hepatitis A in Maltese adults [PDF]
, 1999 The objective of this study was to determine the seroprevalence of hepatitis A virus (HAV) within the adult population of Malta. Serum from blood coincidentally taken for non-acute investigations in patients aged 20 - 85 visiting St. Luke’s Hospital over
Borg, Michael Angelo +1 more
core
Advanced Science, EarlyView.DNA‐Based Genetic and Non‐Genetic Tools for Receptor Engineering. This review highlights recent advances in DNA‐based strategies for receptor engineering, including genetic approaches like domain fusion and site‐directed mutagenesis, as well as non‐genetic methods using functional nucleic acids, DNA nanostructures, and dynamic DNA reactions.
Hexin Nan +4 more
wiley +1 more source
Orthotopic liver transplantation in U.S. veterans under primary tacrolimus immunosupression. [PDF]
, 1996 The evolution and refinement of surgical techniques, per ioperative patient care, and immunosuppression hav~ estab~ished orthoto~ic li~er transplantation (OLTX) as a ~ighly successful therapeutic modality for patients wrth end-stage hver disease.
Doyle, HR +7 more
core
Adaptive Learning Expert System for Diagnosis and Management of Viral Hepatitis
, 2019 Viral hepatitis is the regularly found health problem throughout the world among other easily transmitted diseases, such as tuberculosis, human immune virus, malaria and so on.
Agizew, Henok Yared
core +2 more sources
Differential distribution of hepatitis B core and E antigens in hepatocytes: Analysis by monoclonal antibodies [PDF]
, 1986 Mario U. Mondelli +5 more
openalex +1 more source
Inhibition of AMPKα Pathway by Podocyte GOLM1 Exacerbates Diabetic Nephrology in Mice
Advanced Science, EarlyView.Podocyte Golgi membrane protein 1 interacts with epidermal growth factor receptor to inhibit peroxisome proliferator activated receptor γ, and then inactivates adenosine monophosphate activated protein kinase α pathway, which facilitates diabetes‐related inflammation, oxidative damage, apoptosis, and renal dysfunction.
Peng Xu +14 more
wiley +1 more source
Revista Española de Enfermedades Digestivas, 2008 Crespo Pérez L, Rivero Fernández M
openaire +4 more sources