Results 141 to 150 of about 19,491,478 (363)

Hepatitis E [PDF]

JAMA, 2020
openaire   +2 more sources

ZDHHC12 Palmitoylates HDAC8 to Promote the Progression of Hepatocellular Carcinoma Associated with a Diet High in Saturated Fatty Acids

Advanced Science, EarlyView.
This study identifies ZDHHC12 as a critical mediator of PA‐induced HCC progression. Mechanistically, PA upregulates ZDHHC12 expression through SMARCA4 activation, leading to HDAC8 palmitoylation at Cys244 which blocks HSC70‐mediated lysosomal degradation of HDAC8, thereby promoting HCC development. These findings provide novel mechanistic insights into
Xin Jin, Yulong Hong, Yongqi Zhao, Wensheng Shi, Ruilin Liu, Xinyu You, Chong Yang, Yu Zhang   +7 more
wiley   +1 more source

Is fulminant B hepatitis more common among infants born to e antigen-negative carrier mothers? [PDF]

, 1987
Kunio Okuda
openalex   +1 more source

T2T Genomes Unveil Centromere Architecture and Adaptive Divergence in Large Yellow Croaker (Larimichthys crocea)

Advanced Science, EarlyView.
This study presents telomere‐to‐telomere genome assemblies for two populations of Larimichthys crocea. We identified centromere‐specific tandem repeats invaded by LTR/ERV1 retrotransposons, unique 5S rRNA enrichment patterns, and population‐specific structural variants. Comparative genomic analyses further reveal distinct adaptive mechanisms in the MYD
Yu Cui, Yingbo Yuan, Bi Wang, Baolan Wu, Mingyi Cai, Ming Fang, Weiliang Shen, Xiongfei Wu, Fang Han, Zhiyong Wang   +9 more
wiley   +1 more source

Studies of the “e” Antigen in Acute and Chronic Hepatitis

, 1976
Joseph L. Smith, Bert L. Murphy, Miles O. Auslander, James E. Maynard, Solko S. Schalm, W.H.J. Summerskill, Gary Gitnick   +6 more
openalex   +1 more source

Age‐Specific Prevalence of Hepatitis B e Antigen (HBeAg) and Antibody to HBeAg (Anti‐HBe) among Asymptomatic Hepatitis B Surface Antigen (HBsAg) Carriers in Okinawa and Kyushu, Japan [PDF]

, 1986
Seizaburo Kashiwagi, Jun Hayashi, Hideyuki Nomura, Wataru Kajiyama, Hideyuki Ikematsu, Toshimitsu SHINGU, Kazuo HAYASHIDA, Masaro Kaji   +7 more
openalex   +1 more source

A Novel Class of Multi‐substituted Diaryl Scaffold Derivatives Inhibit Glioblastoma Progression by Targeting CD155

Advanced Science, EarlyView.
Structural modification of clofoctol yielded a novel blood‐brain barrier‐permeable compound, B7, featuring a multi‐substituted diaryl scaffold. B7 demonstrates potent anti‐glioblastoma activity by suppressing glioblastoma stem cells proliferation, migration, and invasion through interactions with five key residues of poliovirus receptor cell adhesion ...
Yong‐jian Wang, Ting Sun, Si‐tu Xue, Zhong‐di Cai, Hong Yi, Miao Lv, Shi‐bo Kou, Rui Liu, Xiao‐zhong Peng, Zhuo‐rong Li   +9 more
wiley   +1 more source

Analysis of current status and influencing factors of hepatitis E knowledge awareness rate among pregnant women in Jiaxing city, Zhejiang province

Zhongguo gonggong weisheng
ObjectiveTo understand the awareness of hepatitis E knowledge and its influencing factors among pregnant women in Jiaxing city, Zhejiang province, and to provide evidence for the development of community hepatitis E prevention and control strategies ...
Feifei GUO, Xiaofei FU, Yuanhang WANG, Yunpeng QI, Wanling ZHOU, Zelin XIANG   +5 more
doaj   +1 more source

Shift from free “small” hepatitis B e antigen to IgG-bound “large” form in the circulation of human beings and a chimpanzee acutely infected with hepatitis B virus

, 1979
Kazuaki Takahashi, Yuzo Miyakawa, Tohru Gotanda, Shunji Mishiro, Mitsunobu Imai, Makoto Mayumi   +5 more
openalex   +1 more source

Hepatitis E virus infection

Nature Reviews Disease Primers, 2018
Asaf Binderman
semanticscholar   +1 more source