Results 151 to 160 of about 641,799 (359)

A Novel Class of Multi‐substituted Diaryl Scaffold Derivatives Inhibit Glioblastoma Progression by Targeting CD155

open access: yesAdvanced Science, EarlyView.
Structural modification of clofoctol yielded a novel blood‐brain barrier‐permeable compound, B7, featuring a multi‐substituted diaryl scaffold. B7 demonstrates potent anti‐glioblastoma activity by suppressing glioblastoma stem cells proliferation, migration, and invasion through interactions with five key residues of poliovirus receptor cell adhesion ...
Yong‐jian Wang   +9 more
wiley   +1 more source

Demonstration of Hepatitis B e Antigen in Hepatitis B Core Particles Obtained from the Nucleus of Hepatocytes Infected with Hepatitis B Virus

open access: bronze, 1979
Hiroshi Yoshizawa   +6 more
openalex   +1 more source

CXCL13 Expression Promotes CAR T Cell Antitumor Activity and Potentiates Response to PD‐1 Blockade

open access: yesAdvanced Science, EarlyView.
This study demonstrates that engineering CAR T cells to express CXCL13 enhances their antitumor efficacy and significantly improves responsiveness to PD‐1 immune checkpoint blockade. CXCL13 promotes T cell persistence, and resistance to early exhaustion via the AKT‐mTOR pathway.
Yang Zhou   +15 more
wiley   +1 more source

FIB‐3 index as a novel age‐independent predictor of liver fibrosis and prognosis in hepatocellular carcinoma patients undergoing hepatectomy

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
Fibrosis‐3 index (FIB‐3) can stratify the risk of the survival and the recurrence‐free survival. The FIB‐3 index is a reliable, age‐independent tool for assessing liver fibrosis and prognosis in HCC patients post‐hepatectomy. Its use may improve clinical outcomes and support personalized treatment strategies. Abstract Background Liver fibrosis is a key
Yuki Imaoka   +13 more
wiley   +1 more source

Prognostic Impact of Hepatectomy Versus Radiofrequency Ablation for Non‐Small Hepatocellular Carcinoma (2–3 cm): A Case‐Matched Study

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
This study aims to elucidate prognostic outcomes of hepatectomy versus RFA for primary 2–3 cm HCC. Hepatectomy may offer superior prognostic benefits, especially in those with elevated AFP levels. The local recurrence rate in hepatectomy is significantly lower than RFA.
Yuki Kitano   +8 more
wiley   +1 more source

Hepatitis B e antigen, DNA polymerase activity, and infection of household contacts with hepatitis B virus

open access: bronze, 1979
Robert P. Perrillo   +6 more
openalex   +1 more source

Age‐Specific Prevalence of Hepatitis B e Antigen (HBeAg) and Antibody to HBeAg (Anti‐HBe) among Asymptomatic Hepatitis B Surface Antigen (HBsAg) Carriers in Okinawa and Kyushu, Japan [PDF]

open access: bronze, 1986
Seizaburo Kashiwagi   +7 more
openalex   +1 more source

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