Results 201 to 210 of about 416,441 (313)

Characterization and immunogenicity of nanoparticle vaccines displaying embecovirus spike proteins

open access: yesBiotechnology Progress, EarlyView.
Virus‐like particle vaccines displaying spike proteins from OC43, HKU1 A, and HKU1 B were evaluated in mice for their ability to elicit antibodies against the spike proteins from OC43, HKU1 A, HKU1 B, and HKU1 C. Abstract Endemic human coronaviruses OC43 and HKU1 cause widespread respiratory infections and can be associated with severe illness in ...
Peter J. Halfmann   +6 more
wiley   +1 more source

Hepatitis E virus-associated neurological injury and neurotropic cellular mechanisms. [PDF]

open access: yesFront Cell Infect Microbiol
Guo Z   +10 more
europepmc   +1 more source

Effect of aesthetic crown lengthening on life quality and self‐esteem: 2‐year study

open access: yesClinical Advances in Periodontics, EarlyView.
Abstract Background A gummy smile can result from several factors, often leading to a disharmonious appearance and causing physical and psychological discomfort for the patient. This study aimed to evaluate changes in self‐esteem and quality of life for patients, as well as the recidivism rate, following aesthetic crown lengthening (ACL) surgery ...
Leticia S. Arroteia   +7 more
wiley   +1 more source

Development of a CRISPR-Cas13-based antiviral strategy against hepatitis E virus. [PDF]

open access: yesJHEP Rep
Richter E   +6 more
europepmc   +1 more source

Bemnifosbuvir: An HCV NS5B Inhibitor With Multiple Modes of Action

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Bemnifosbuvir (BEM) is a potent, pan‐genotypic inhibitor targeting the hepatitis C virus (HCV) NS5B polymerase. Its antiviral activity was evaluated in an ascending dose phase I clinical trial involving 30 patients treated once a day for 7 days. After treatment initiation, plasma HCV RNA declined in a biphasic manner with a mean reduction of 2.3 log10 ...
Carolin Zitzmann   +4 more
wiley   +1 more source

Hepatitis E virus infection in a single center in Japan. [PDF]

open access: yesClin Exp Hepatol
Ashina K   +6 more
europepmc   +1 more source

Preserved Spermatogenesis and Hormonal Function in Men Receiving a Pretomanid Regimen (BPaMZ) for Pulmonary Drug‐Resistant Tuberculosis

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Pretomanid is a component of the World Health Organization‐recommended treatment regimen for drug‐resistant tuberculosis in patients aged ≥ 14 years. While preclinical rodent studies identified testicular toxicity as a potential clinical liability at elevated doses, no corresponding effects were observed in nonhuman primates nor clinical hormone ...
Pauline Howell   +13 more
wiley   +1 more source

Hepatitis E (Hepatitis E virus)

open access: yes, 2022
Jokelainen, Pikka   +4 more
openaire   +1 more source

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