Results 261 to 270 of about 641,799 (359)

Pharmacokinetics, Safety, and Skin Irritation and Sensitization Potential of Clascoterone Cream in Early‐Phase Clinical Study Participants

Clinical Pharmacology in Drug Development, EarlyView.
Abstract Clascoterone is an androgen receptor inhibitor approved for the treatment of acne vulgaris in patients 12 years of age and older. Here, we report results of 5 phase 1 studies that assessed the pharmacokinetics (PK), safety, and skin irritation and sensitization potential of clascoterone cream 1% in healthy participants and patients with acne ...
Andrea Francesco Daniele Di Stefano, Milko Massimiliano Radicioni, Gerhard Garhöfer, Martina Cartwright, Markus Müller, Iris Kopeloff, Luigi Moro, Nicholas Squittieri, Alessandro Mazzetti   +8 more
wiley   +1 more source

A serum exosomal microRNA‐based artificial intelligence diagnostic model for highly accurate detection of hepatocellular carcinoma

Cancer Communications, EarlyView.
Jin‐Seong Hwang, Sugi Lee, Gyeonghwa Kim, Hoibin Jeong, Kiyoon Kwon, Eunsun Jung, Yuna Roh, Taesang Son, Hana Lee, Moo‐Seung Lee, Kyoung‐Jin Oh, Hye Won Lee, Yu Rim Lee, Soo Young Park, Won Young Tak, Hyun Seung Ban, Hyun‐Soo Cho, Mi‐Young Son, Jang‐Seong Kim, Keun Hur, Dae‐Soo Kim, Tae‐Su Han   +21 more
wiley   +1 more source

Night‐Time Chronotherapy with Methylprednisolone Prevents an Acute Rejection in Pediatric Patients with Liver Transplantation: A Randomized Clinical Trial

Clinical Pharmacology &Therapeutics, EarlyView.
Concept of methylprednisolone chronotherapy to prevent acute rejections. While endogenous cortisol secretion rises in the early morning, the number of lymphocytes in the blood is higher at night, thus exhibiting an antiphase pattern to cortisol secretion. Therefore, compared with the daytime, the infiltration of lymphocytes into immune‐reactive tissues
Kentaro Ushijima, Yukihiro Sanada, Shinya Otomo, Keiko Ogaki, Taiichi Wakiya, Noriki Okada, Yuta Hirata, Yasuharu Onishi, Yasunaru Sakuma, Yukiyo Wada, Akio Fujimura, Koichi Mizuta   +11 more
wiley   +1 more source

Identification and pathogenicity of avian hepatitis E virus from quail. [PDF]

BMC Vet Res
Li J, Zhang Y, Liu J, Xu S, Gao X, Li X, DanBaZhaXi, Zhao Q, Zhou EM, Chen Y, Liu B.   +10 more
europepmc   +1 more source

Antibody to Hepatitis B e Positive Hepatitis Induced by Withdrawal of Steroid Therapy for Polymyositis: Response to Interferon-Alpha and Cyclosporin A.

, 1998
Kimio Nakanishi, Maki Ishikawa, Masahito Nakauchi, Atsushi Sakurai, Kazuaki Doi, Yoshiyasu Taniguchi   +5 more
openalex   +2 more sources

Populations Addressed in Vaccines Approved via the European Medicines Agency

Clinical Pharmacology &Therapeutics, EarlyView.
Therapeutic and prophylactic agents require robust evidence before patient use. Randomized controlled trials are essential for evaluating safety and efficacy but often exclude specific populations that are also targets for the intervention. This study assessed which populations are included in vaccine registration studies and/or addressed in label ...
Débora D. Gräf, Lukas Westphal, Jonathan Kimmelman, Christine E. Hallgreen   +3 more
wiley   +1 more source

Unmasking the Duo: Wilson's Disease in the Context of Lupus and Existing Hepatitis E Coinfection. [PDF]

Clin Case Rep
Hussain SM, Khan A, Anas Z, Khan Z, Abbasi A, Haque MA.   +5 more
europepmc   +1 more source

Transendocardial injection of expanded autologous CD34+ cells after myocardial infarction: Design of the EXCELLENT trial

ESC Heart Failure, Volume 12, Issue 2, Page 1455-1463, April 2025.
Abstract Aims The extent of irreversible cardiomyocyte necrosis after acute myocardial infarction (AMI) is a major determinant of residual left ventricular (LV) function and clinical outcome. Cell therapy based on CD34+ cells has emerged as an option to help repair the myocardium and to improve outcomes.
Jerome Roncalli, François Roubille, Nicolas Meyer, Giulio Pompilio, Lionel Leroux, Philippe Henon, Guillaume Trebuchet, Anthony Criquet, Matthieu de Kalbermatten, Eric Saloux, Alain Manrique, Pierre‐Yves Marie, Deepak L. Bhatt, Scott D. Solomon, Gilles Montalescot, David E. Newby, Faiez Zannad, on behalf of the EXCELLENT Trial Investigators   +17 more
wiley   +1 more source

High prevalence of hepatitis E and rat hepatitis E viruses in wastewater in Gothenburg, Sweden. [PDF]

One Health
Churqui MP, Ghaleb M, Tunovic T, Frankal M, Enache L, Nyström K, Lagging M, Wang H.   +7 more
europepmc   +1 more source

Type E hepatitis: State of the Art

, 1997
Mikhail S. Balayan
openalex   +1 more source