Results 201 to 210 of about 274,206 (262)

Reactive oxygen species promotion drives auranofin's antiviral activity against hepatitis E virus. [PDF]

J Virol
Tiller K, Williams ST, Wang B, Tian D, Meng X-J, Weger-Lucarelli J.   +5 more
europepmc   +1 more source

Enhanced CRISPR‐cas systems for genome editing and molecular diagnostics

Interdisciplinary Medicine, EarlyView.
This review systematically summarizes the major optimization strategies for CRISPR‐Cas systems, focusing on the engineering of Cas proteins, guide RNAs, reporter probes, and the incorporation of chemical additives. The aim is to enhance editing precision and diagnostic capability, thereby expanding the CRISPR system's potential for broader biomedical ...
Sheng Li, Han Li, Bojie Chen, Ling Jiang, Keyu Long, Jiaqi Lang, Xingxiang Pu, Erhu Xiong   +7 more
wiley   +1 more source

Seroprevalence of Hepatitis A Virus and Hepatitis E Virus Among Patients With Acute Viral Hepatitis in a Tertiary Care Hospital: A Retrospective Study. [PDF]

Cureus
Jagatdeo K, Roy A, Panigrahi K, Thatoi N, Sahoo JP, Pathi BK.   +5 more
europepmc   +1 more source

Improving Linkage to the HCV Care Cascade in Nonspecialist Settings: Evaluation of the Performance and Triage Utility of the Elecsys HCV Duo Assay in Japan

Journal of Clinical Laboratory Analysis, EarlyView.
In nonspecialist departments, most anti‐HCV–positive individuals do not proceed to RNA testing. The Elecsys HCV Duo assay simultaneously detects anti‐HCV antibodies and core antigen from a single blood draw and preferentially identifies patients with clinically meaningful viral loads.
Hiroko Setoyama, Takehisa Watanabe, Shiho Miyase, Masakuni Tateyama, Motohiko Tanaka, Nobuhiro Minami, Masato Sasaki, Shunpei Hashigo, Kotaro Fukubayashi, Shotaro Ishii, Mutsuo Koga, Ryo Ichikawa, Hirofumi Iwashita, Yoshinari Sakai, Toshihiko Motohara, Kohei Tomita, Akinori Nakata, Yutaka Kai, Takeyasu Kounoe, Katsuki Haraoka, Takako Inoue, Takanori Suzuki, Kentaro Matsuura, Yasuhito Tanaka   +23 more
wiley   +1 more source

Unveiling hepatitis E virus diversity in Sudan's internally displaced populations: a molecular epidemiology approach. [PDF]

Trop Med Health
Osman HA, Bakr WMK, Hashish MH, Elkhidir IM, Bedri S, Oyola SO, Norder H, Abd El-Wahab EW.   +7 more
europepmc   +1 more source

Soluble B7‐H6 as a Novel Diagnostic Biomarker for Post‐Hepatitis B Cirrhosis: A Clinical Value Study

Journal of Clinical Laboratory Analysis, EarlyView.
This study investigates the potential of soluble B7‐H6 (sB7‐H6) as a novel diagnostic biomarker for post‐hepatitis B cirrhosis. The infographic visually presents the following key points: (1) Liver Disease Progression: Chronic hepatitis B (CHB) progresses to liver cirrhosis (LC), with serum sB7‐H6 levels increasing stepwise as the disease advances. (2)
Kaiyong Chen, Luxuan Yang, Huaiwu Fu, Lei Cao, Zhu Li   +4 more
wiley   +1 more source

The Differential Effects of Immunosuppressants on Hepatitis E Virus Replication and the Triggered Inflammatory Responses in Macrophages. [PDF]

J Viral Hepat
Zhou J, Liu K, Boor PPC, Pan Q, Ayada I.
europepmc   +1 more source

A Comprehensive Study of Bidirectional Interactions Between the Human Microbiome and Blood Malignancies and Hematologic Conditions: Focus on Novel Therapeutic Strategies

Journal of Clinical Laboratory Analysis, EarlyView.
Microbiota‐targeted therapeutic strategies in hematological disorders. aHSCT: Transplanted immune cells from the donor may attack the recipient's tissues, especially when damage to the intestinal epithelium disrupts the gut microbiota, contributing to GVHD. Maintaining a balanced gut microbiota that supports immune regulation helps reduce GVHD risk and
Alireza Molajafari, Hadi Sedigh Ebrahim‐Saraie, Majid Taati Moghadam, Meysam Hasannejad‐Bibalan   +3 more
wiley   +1 more source

Virological and immunological determinants of hepatitis E virus infection outcomes. [PDF]

Curr Opin Virol
Wang X, Bian L, Ha EH, Wang L, O'Shaughnessy K, Zheng Y, Feng Z, Chen WB, Wu X.   +8 more
europepmc   +1 more source