Results 281 to 290 of about 473,635 (345)

Curcuminoids amplify host innate antiviral immunity via the CRYAB‐RBM26 axis in viral infection

iMeta, EarlyView.
DMC/CUR antagonize viral hijacking of host nucleic acid resources and finely regulate the induction and effector phases of the type I interferon (IFN‐I) pathway through the CRYAB‐RBM26 axis. This molecular axis serves as a key downstream regulator for DMC/CUR activation of the IFN‐I pathway.
Tingting Chen, Xiang Wang, Guangyuan Zhang, Lu Wang, Junhao Wan, Lirong Tan, Xinyue Fan, Siqin Meng, Zhixing Jin, Yuzhang Liang, Haoze Li, Ziyuan Wan, Xiaotong Xu, Yan Zhang, Li Qin, Anna Malashicheva, Yu Du, Guangchao Zang, Guixue Wang   +18 more
wiley   +1 more source

Absence of hepatitis E virus RNA in bovines from Portugal. [PDF]

Vet Res Commun
Santos-Silva S, Palmeira JD, Ferreira H, Romalde JL, Gonçalves HMR, Van der Poel WHM, Nascimento MSJ, Rivero-Juarez A, Mesquita JR.   +8 more
europepmc   +1 more source

Microbial metabolites in tumor epigenetic regulation

iMeta, EarlyView.
The gut microbiome modulates tumor epigenetic regulation through bioactive metabolites derived from dietary substrates. Microbiota‐produced SCFAs, secondary BAs, one‐carbon metabolites, and tryptophan‐derived ligands regulate histone acetylation, DNA methylation, and chromatin remodeling via HDAC, DNMT, AhR, and metabolic cofactor‐dependent pathways ...
Wangzheqi Zhang, Haoling Zhang, Yan Liao, Shuya Jiang, Haolong Zhang, Chenwei Huang, Zhijing Song, Rui Zhao, Ping Lu, Xiaohong Kang, Eryan Kong, Yalin Zhu, Wei Wang, Xuesong Liu, Yisheng Chen, Zhiwen Luo, Zhaoyu Li, Di Wang, Na Xing, Yadong Guo, Jingjing Zhang, Xiaojing Wang, Wenyi Wang, Mowaffaq Adam, Bakiah Shaharuddin, Muhamad Yusri Musa, Doblin Sandai, Chenglong Zhu, Aimin Jiang, Peng Luo, Zhijie Zhao, Zui Zou   +31 more
wiley   +1 more source

Hepatitis E Virus-Associated Endocapillary Proliferative Glomerulonephritis in an Immunocompetent Adult. [PDF]

Kidney Int Rep
Miyazaki T, Hirai T, Nishida H, Fujii T, Isomura A, Nagahama K.   +5 more
europepmc   +1 more source

PD‐1/PD‐L1 in Hepatocellular Carcinoma (2014–2024): A Combined Macro and Micro Analysis of Immunotherapy Implications

iNew Medicine, EarlyView.
ABSTRACT Hepatocellular carcinoma (HCC) represents a significant global health issue, with the PD‐1/PD‐L1 axis serving a pivotal target for immunotherapy in this malignancy. However, a comprehensive bibliometric analysis of PD‐1/PD‐L1 research in HCC is lacking.
Xingyu Zhu, Lin Tang, Hongyan Li, Hao Li, Jiamei Wang   +4 more
wiley   +1 more source

Glucose-6-phosphate dehydrogenase deficiency facilitates hepatitis E virus entry and aggravates liver injury. [PDF]

Virol J
Chen D, Hu X, Xue Y, Xia F, Li M, Liu J, Huang F.   +6 more
europepmc   +1 more source

Epigenetic Regulation in the Pathogenesis of Renal Inflammation: Insights and Therapeutic Potentials

iNew Medicine, EarlyView.
ABSTRACT Renal inflammation is a common pathological process in various kidney diseases, often initiated by factors such as toxins, ischemia, or autoimmune reactions. This inflammatory response can result in structural damage and a rapid decline in renal function.
Yu‐Hang Dong, Xiao‐Yu Shen, Han‐Cheng Jin, Xiang‐Yu Li, Hao He, Xiao‐Ming Meng   +5 more
wiley   +1 more source

Epidemiology and seroprevalence of Hepatitis E Virus in Nigeria and its African context: a review and one health perspective. [PDF]

Infez Med
Olowu BI, Tinubu OB, Solesi OO, Ochi E, Ahmed SO, Zakariya ME.   +5 more
europepmc   +1 more source

The T‐Cell Response Mechanism in Human Papillomavirus‐Associated Cervical Cancer and New Strategies for Immunotherapy

iNew Medicine, EarlyView.
ABSTRACT Human papillomavirus (HPV) is a double‐stranded DNA virus that infects human skin and mucosal tissues exclusively. The German scientist Harald zur Hausen was awarded the 2008 Nobel Prize in Physiology or Medicine for his discovery of the link between HPV infection and cervical cancer.
Fang Zhu, Farah Nazir, Ying Zhou, Yuhua Shang, Hongliang He, Tengchuan Jin   +5 more
wiley   +1 more source

Seroprevalence and determinants of hepatitis E virus infection among people living with HIV in Chiang Mai, Thailand: a cross-sectional analysis. [PDF]

Sci Rep
Chakma R, Jindaphun K, Umer M, Khamai L, Kosashunhanan N, Srithanaviboonchai K, Khamduang W, Hongjaisee S.   +7 more
europepmc   +1 more source