Results 91 to 100 of about 21,046 (260)

Cytoskeletal reorganization and repolarization of hepatocarcinoma cells in APA microcapsule to mimic native tumor characteristics

open access: yes, 2006
Culture of human hepatocarcinoma cells in three-dimensional structure or spheroid represents a unique opportunity to recapitulate aspects of cell homeostasis and to better reflect the characteristics of native hepatic tumor.
Xiong, Y   +7 more
core   +1 more source

Advances in the Protective Effects and Mechanisms of β‐Aminoisobutyric Acid in Maintaining Multi‐Organ Homeostasis

open access: yesMedicine Bulletin, EarlyView.
ABSTRACT β‐Aminoisobutyric acid (BAIBA) is an exercise‐responsive myokine/metabolite released by skeletal muscle and has attracted increasing interest as a potential exercise mimetic and therapeutic candidate in preclinical research. BAIBA acts locally in skeletal muscle and can also reach distal organs through the circulation, contributing to the ...
Hao‐Zhe Wang   +5 more
wiley   +1 more source

Hsp90 Inhibition on the Western Blot: N‐Terminal Versus C‐Terminal Inhibitors in Breast Cancer

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT Heat shock protein 90 (Hsp90) is an established and clinically validated anticancer target. By regulating the folding and maturation of diverse client proteins, it is indirectly involved in carcinogenesis. Key breast cancer oncogenic drivers, including estrogen receptor, progesterone receptor, and human epidermal growth factor receptor 2, are ...
Jaka Dernovšek   +3 more
wiley   +1 more source

Evaluation of Selenite Effects on Selenoproteins and Cytokinome in Human Hepatoma Cell Lines

open access: yesMolecules, 2013
The need to explore new alternative therapeutic strategies and chemoprevention methods for hepatocellular carcinoma is growing significantly. Selenium is a trace element that plays a critical role in physiological processes, and is used in cancer ...
Susan Costantini   +10 more
doaj   +1 more source

Hepatocarcinoma pediculado

open access: yesCirugía del Uruguay, 1988
Se presenta una observación excepcional de hepatocarclnoma pediculado que asentaba en un parénquima hepático previamente alterado (esteatosis masiva). Planteamos como hipótesis que su origen asiente en un lóbulo aberrante del hígado dado las dimensiones enormes adquiridas por el tumor.
Nicolás Davidenko   +3 more
openaire   +1 more source

Up-regulatedmiR-500aenhances hepatocarcinoma metastasis by repressing PTEN expression

open access: yes, 2017
It has been shown that miR-500a may play an important role in the metastasis of hepatocarcinoma. The present study is to explore the influence of miR-500a on hepatocarcinoma proliferation and metastasis, and the related molecular mechanism. The levels of
Yufeng Zhao, Yaqiang Wang, Yuehui Wang
core   +1 more source

Seeded‐Growth of ZIF‐8 onto Magnetic Nanoparticles: Smart Nanocarriers with Ultrahigh Drug Loading for AMF‐Triggered Release

open access: yesSmall, EarlyView.
We developed core‐shell iron oxide@ZIF‐8 magnetic‐MOF nanohybrids via a seeded growth method for magnetic hyperthermia‐triggered drug delivery. Cubic cores and thinner shells maximized heating. In‐situ doxorubicin encapsulation achieved 98% loading, better than surface encapsulation. Polymer coating improved stability.
Ana Maria Panaite   +11 more
wiley   +1 more source

Hepatocarcinoma. Hemoperitoneo

open access: yesCirugía del Uruguay, 1974
Presentamos un caso de carcinoma primitivo de higado, en el cual destacamos: la forma de presentación clínica, la aparición de un hígado no cirrótico, la presencia de un hemoperitoneo, y la aparición multicéntrica del tumor.
Juan Chifflet   +2 more
openaire   +1 more source

Papel del receptor de dioxina en el hepatocarcinoma

open access: yes, 2022
Programa de doctorado en Biología Molecular y Celular, Biomedicina y BiotecnologíaActualmente no disponemos de un sistema de estadiaje ideal que nos permita identificar a aquellos pacientes que van a presentar un peor pronóstico cuando son ...
Armas Conde, Noelia de
core  

Peptide‐directed nanovehicles enabling tumor‐selective ROS amplification and antitumor immunity

open access: yesVIEW, EarlyView.
Cancer cells are vulnerable to oxidative stress, yet exploit immune tolerance to escape destruction. In contrast, their metabolic profile is markedly altered to support rapid proliferation, accompanied by elevated production of reactive oxygen species (ROS).
Manuela Calin   +3 more
wiley   +1 more source

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