Among children with advanced hepatoblastoma in this selected cohort, survival outcomes were consistent with those reported in the literature, while treatment‐related toxicity remained limited. Tailoring chemotherapy according to surgical timing may represent a feasible approach in high‐risk patients, without an apparent increase in treatment‐related ...
Claudia Pellegrinelli +9 more
wiley +1 more source
Technology-Critical Element Exposure Reveals Divergent Toxicity in Different Human Cells Despite Comparable Uptake. [PDF]
Magdaș TM +8 more
europepmc +1 more source
Zebrafish provide a high‐throughput, optically transparent platform for cancer and drug screening. Their ~80% genetic homology, xenograft compatibility, and transgenic strains enable targeted photosensitizer screening, real‐time ROS and tumor imaging, and mechanistic assays, while fish embryo acute toxicity (FET) and in vitro tests streamline toxicity ...
Ethan Wilson +5 more
wiley +1 more source
A Quarter Century of EHD Protein Research: From Endosomal Recycling to Ciliopathies
Human EHD protein subcellular localization. ABSTRACT Eps15 homology domain‐containing proteins comprise a conserved family of membrane‐remodeling ATPases that regulate endocytic trafficking, membrane fission, receptor recycling, primary ciliogenesis and membrane dynamics across eukaryotes. Since the initial identification of EHD1 and its Caenorhabditis
Devin Frisby +3 more
wiley +1 more source
Cytochrome P450 enzymes as modulators of oncogenic signaling via the Wnt/β-catenin signaling pathway. [PDF]
Braeuning A.
europepmc +1 more source
Anti-Hepatocarcinoma Activity and Mechanism of Isosendanin and Its Novel Structural Analogues Isolated from the Bark of <i>Melia azedarach</i> L.: In Vitro and In Vivo Studies. [PDF]
Huang Y +6 more
europepmc +1 more source
Diterpenoids from the aerial parts of <i>Isodon serra</i> and their anti-hepatocarcinoma potential. [PDF]
Wu H +10 more
europepmc +1 more source
Evaluating the Antitumor Effect of Root Extract of Salvadora persica in Hepatocarcinoma Through the Induction of Apoptosis via an Intrinsic Pathway: An In Vitro Study. [PDF]
Latif F, Qun K, Lu M.
europepmc +1 more source
In Vitro Antineoplastic Effects of <i>Zataria multiflora</i>: A Systematic Review of Mechanisms, Selectivity, and Synergy. [PDF]
Khanahmad A +6 more
europepmc +1 more source

