Results 131 to 140 of about 600,868 (344)

Integrating bulk and single-cell RNA sequencing reveals SH3D21 promotes hepatocellular carcinoma progression by activating the PI3K/AKT/mTOR pathway.

PLoS ONE
As a novel genetic biomarker, the potential role of SH3D21 in hepatocellular carcinoma remains unclear. Here, we decipher the expression and function of SH3D21 in human hepatocellular carcinoma. The expression level and clinical significance of SH3D21 in
Wangxia Tong, Na Qin, Tao Lu, Li Liu, Rong Liu, Jibing Chen, Ning Luo   +6 more
doaj   +1 more source

Modularity of the metabolic gene network as a prognostic biomarker for hepatocellular carcinoma [PDF]

arXiv, 2017
Abnormal metabolism is an emerging hallmark of cancer. Cancer cells utilize both aerobic glycolysis and oxidative phosphorylation (OXPHOS) for energy production and biomass synthesis. Understanding the metabolic reprogramming in cancer can help design therapies to target metabolism and thereby to improve prognosis.
arxiv  

Further Observations on Polycythemia in Hepatocellular Carcinoma [PDF]

, 1961
Y Kan, A. J. S. McFadzean, D. Todd, S. C. Tso   +3 more
openalex   +1 more source

Transarterial RAdioembolization versus ChemoEmbolization for the treatment of hepatocellular carcinoma (TRACE) : study protocol for a randomized controlled trial [PDF]

, 2012
Background: Hepatocellular carcinoma is a primary malignant tumor of the liver that accounts for an important health problem worldwide. Only 10 to 15% of hepatocellular carcinoma patients are suitable candidates for treatment with curative intent, such ...
Al Younis, Imad, Coenraad, Minneke J, Defreyne, Luc, Lam, Marnix GEH, Lambert, Bieke, Seinstra, Beatrijs A, van den Bosch, Maurice AAJ, van Erkel, Arian R, van Erpecum, Karel J, van Hoek, Bart, Van Vlierberghe, Hans, Verkooijen, Helena M   +11 more
core   +1 more source

Achieving Optimal Health With Host‐Directed Therapies (HDTs) in Infectious Diseases—A New Horizon

Advanced Therapeutics, EarlyView.
Host‐directed therapies (HDTs) represent a transformative approach in infectious disease management by targeting host factors to enhance immune responses and inhibit viral replication. This innovative strategy leverages advanced genomics and gene editing technologies, offering promising avenues for improved patient outcomes and a new horizon in ...
Amol D. Gholap, Pankaj R. Khuspe, Sagar R. Pardeshi, Md Jasim Uddin, Ushasi Das, Navnath T. Hatvate, Satish Rojekar, Prabhanjan Giram, Mohammad Khalid, Yahya E. Choonara, Md. Faiyazuddin   +10 more
wiley   +1 more source

Hepatocellular carcinoma in infancy and childhood in Ibadan, Western Nigeria. [PDF]

, 1967
Adrian Williams, G. M. Edington, P-C Obakponovwe   +2 more
openalex   +1 more source

Clinical applications of squamous cell carcinoma antigen-immunoglobulins M to monitor chronic hepatitis C [PDF]

, 2015
Hepatitis C virus (HCV) is the main cause of chronic liver disease and cirrhosis in Western countries. Over time, the majority of cirrhotic patients develop hepatocellular carcinoma (HCC), one of the most common fatal cancers worldwide - fourth for ...
Fassina, Giorgio, Gallotta, Andrea, MARTINI, ANDREA, PONTISSO, PATRIZIA   +3 more
core   +1 more source

Opportunities in Therapeutic mRNA Stabilization: Sequence, Structure, Adjuvants and Vectors

Advanced Therapeutics, EarlyView.
Current mRNA lipid nanoparticles rely on cold storage, which increases the cost and reduces access to the vaccines. As mRNA expands to other clinical opportunities, better methods to stabilize the medicines during shipping, storage, and delivery are needed.
Joshua A. Choe, Jacobus Burger, Jamie Jones, Apurva Panjla, William L. Murphy   +4 more
wiley   +1 more source

Accelerated Bone Healing via Electrical Stimulation

Advanced Science, EarlyView.
Electrical stimulation significantly impacts bone healing by enhancing osteoblast proliferation, differentiation, and vascularization through calmodulin/calcineurin/NFAT signaling. It also boosts macrophage function and cell migration, presenting a comprehensive approach to accelerating bone repair.
Jianfeng Sun, Wenqing Xie, Yuxiang Wu, Zhou Li, Yusheng Li   +4 more
wiley   +1 more source

Complete necrotization of hepatocellular carcinoma by chemotherapy and subsequent intravascular coagulation.A case report [PDF]

, 1978
Toshinori Harada, Y. Makisaka, Hideo Nishimura, Kunio Okuda   +3 more
openalex   +1 more source