Results 261 to 270 of about 690,479 (320)

Hepatectomy in children. [PDF]

, 1982
Iwatsuki, S, Starzl, TE
core  

RUNX1/SLAMF3 Axis Drives Immunosuppression to Contribute to Colorectal Cancer Liver Metastasis by Blocking Phagocytosis and Depleting C1QC+ Tumor‐Associated Macrophages

Advanced Science, EarlyView.
This study identifies the RUNX1/SLAMF3 axis as a key driver of colorectal cancer liver metastasis (CRLM). SLAMF3 suppresses macrophage phagocytosis and depletes C1QC⁺ tumor‐associated macrophages, promoting an immunosuppressive microenvironment. Targeting this axis restores macrophage and CD8⁺ T cell activity and reduces metastasis.
Yinheng Luo, Xiaoli Jin, Lan Huang, Dejia Zeng, Nan Zhang, Shiyu Tang, Shu Luo, Samina Ejaz Syed, Ruiwu Dai, Qiu Li, Shufang Liang   +10 more
wiley   +1 more source

Hexahydrocurcumin suppresses hepatocellular carcinoma by regulating TRIM23/MBNL1 pathway. [PDF]

Sci Rep
Wang M, Weng C, Xu J, Xu K.
europepmc   +1 more source

EGFR‐TKIs Induced DPP4 Drives Metabolic Reprogramming of Persister Cells in Lung Cancer

Advanced Science, EarlyView.
Drug‐tolerant persister (DTP) cells emerge early during EGFR‐TKI treatment, preceding the development of acquired resistance. Elevated DPP4 in DTP cells drives metabolic reprogramming and antioxidant adaptation, promoting cell survival under drug pressure.
Yuanzhou Zhang, Xiaojun Zhang, Xupeng Yang, Xingshi Chen, Yuehong Wang, Jingying Hu, Rui Liu, Xiaoying Luo   +7 more
wiley   +1 more source

Advancing Adjuvant Immunotherapy in Hepatocellular Carcinoma: A Comprehensive Review. [PDF]

Immunotargets Ther
Akabane M, Chatzipanagiotou OP, Imaoka Y, Schenk A, Pawlik TM.   +4 more
europepmc   +1 more source

Membranous obstruction of the inferior vena cava: Etiology and relation to hepatocellular carcinoma

, 1982
Kunio Okuda
openalex   +1 more source

PLAUR+ Neutrophils Drive Anti‐PD‐1 Therapy Resistance in Patients with Hepatocellular Carcinoma by Shaping an Immunosuppressive Microenvironment

Advanced Science, EarlyView.
The present study reveals that PLAUR+ neutrophils are enriched in immunotherapy non‐responders and correlate with poor prognosis. PLAUR+ neutrophils dictate immunotherapy resistance in hepatocellular carcinoma by forming an immunosuppressive tumor microenvironment characterized by CD8+ T cell exclusion and macrophage‐dependent immune suppression.
Shaoqing Liu, Yanzhao Zhou, Gaoxiang Li, Bingwen Zhu, Fang Wu, Jinxue Zhou, Xiaobing Chen, Bo Qin, Yanxia Gao, Fazhan Wang, Yong Jiang, Wenxin Xu   +11 more
wiley   +1 more source

Molecular insights into early malignant transition of hepatocellular carcinoma

bioRxiv
Zhang Z, Li H, Chen L, lu T, Shentu X, Liu Y, Ji S, Qiu Z, Zou Y, Wen H, Han J, Jiang Z, Fan J, Li D, Mesropian A, Pinyol R, Llovet JM, Dong H, Ji Y, Hui L.   +19 more
europepmc   +2 more sources

Role of Immunotherapy in the Treatment of Hepatocellular Carcinoma. [PDF]

Curr Oncol
Dobrosotskaya IY, Kumar R, Frankel TL.
europepmc   +1 more source