Results 261 to 270 of about 715,584 (321)

Editorial: Hepatocellular carcinoma: novel treatment strategies, volume III. [PDF]

Front Med (Lausanne)
Feng F, Xu X.
europepmc   +1 more source

ZDHHC2‐Dependent Palmitoylation Dictates Ferroptosis and Castration Sensitivity in Prostate Cancer via Controlling ACSL4 Degradation and Lipid Peroxidation

Advanced Science, EarlyView.
Our study reveals a novel mechanism by which palmitoylation regulates ferroptosis and enzalutamide resistance in prostate cancer. Under enzalutamide resistance, the FOXA1/CXXC5/TET2 complex induces aberrant upregulation of ZDHHC2, which subsequently suppresses ferroptosis by mediating S‐palmitoylation of USP19 and degradation of ACSL4 protein in CRPC ...
Shuai Shao, Wei Li, Yulong Hong, Ruijiang Zeng, Liang Zhu, Lu Yi, Yuan Li, Yinhuai Wang, Haojie Huang, Xuewen Jiang, Xin Jin   +10 more
wiley   +1 more source

A Patient Charter to Improve Care for Hepatocellular Carcinoma. [PDF]

J Hepatocell Carcinoma
Hassan Y, Kautz A, James C, Lee D, Langenbacher D, Bouffet E, Chakowa J, Hicks J, Ward JW, Kuschnereit LA, Allaire M, Zhang T, Huang Chi Z.   +12 more
europepmc   +1 more source

AP2M1 Amplification Orchestrates Notch‐Mediated Chemoresistance in Hematopoietic Stem Cells of Acute Myeloid Leukemia Patients

Advanced Science, EarlyView.
The precise regulation of AP2M1 is essential for normal hematopoiesis. Overexpression of AP2M1 negatively affects the clinical outcomes of AML patients. Upregulation of AP2M1 enhances stemness and chemoresistance in HSPC cells of AML. AP2M1 modulates NOTCH1 expression, enhancing the Notch1 signaling pathway.
Hansong Lee, Eun Kyoung Kim, Hee Young Ju, Chae Rin Lee, Soyul Ahn, Eun‐Sun Kim, Kyungjae Myung, Won Kyu Kim, Su‐Yeon Cho, Yujin Kwon, Dokyoung Kim, Yeuni Yu, Eun Jung Kwon, Hyomin Kim, Seong Ik Mun, Dong Min Lim, Kihun Kim, Hye Jin Heo, Seung Eun Baek, Sun Young Lee, Hyunsoo Cho, Eun Young Choi, Tae Sik Goh, Ninib Baryawno, Dongjun Lee, Ki Sun Jung, Keon Hee Yoo, Chang‐Kyu Oh, Yun Hak Kim   +28 more
wiley   +1 more source

CD24 as a Novel Radiopharmaceutical Target for Hepatocellular Carcinoma. [PDF]

J Nucl Med
Makala H, Sheehan-Klenk J, Lee W, Chung JY, Baidoo KE, Nambiar D, Choyke PL, Escorcia FE.   +7 more
europepmc   +1 more source

An autopsied case of hepatocellular carcinoma associated with a skin invasion via ligamentum teres hepatis.

, 1988
Yoshiharu Motoo, Kenzo Ikeda, Naoki Yamashita, Akihiko Furusawa, Nobuyoshi Tanaka, S Katsuta, Kenichi Kobayashi, Nobutaka Hattori   +7 more
openalex   +2 more sources

Spatial Transcriptomics and snRNA‐seq Expose CAF Niches Orchestrating Dual Stromal‐Immune Barriers in Hepatocellular Carcinoma

Advanced Science, EarlyView.
HmmyCAFs may form a triple immunosuppressive niche: possibly secrete ECM (POSTN, etc.) as physical barriers to block CD8⁺ T cells, induce CD8⁺ T exhaustion via those molecules, and use HIF‐1α‐driven metabolism to create acidic, nutrient‐poor microenvironments that suppress T cells.
Yingxue Li, Changxiang Huan, Haoting Sun, Wei Zhang, Zhen Guo, Chuanyu Li, Jia Yao, Zhiqi Zhang, Shizhe Yu, Qiongzhu Dong, Lunxiu Qin, Jinze Li, Lianqun Zhou   +12 more
wiley   +1 more source

Evaluating the GALAD Score for Detection of Hepatocellular Carcinoma in Patients With Cirrhosis. [PDF]

J Clin Gastroenterol
Vo TD, Mai SH, Lam HT.
europepmc   +1 more source

Modern approach to hepatocellular carcinoma treatment. [PDF]

World J Hepatol
Cortese F, Anagnostopoulos F, Bazzocchi MV, Caringi S, Pisani AR, Renzulli M, Paraskevopoulos I, Laera L, Surgo A, Spiliopoulos S, Memeo R, Inchingolo R.   +11 more
europepmc   +1 more source