Results 91 to 100 of about 21,587 (248)

Cardiorenal and hepatorenal syndrome

Journal of Pediatric Critical Care, 2018
Cardiorenal syndrome(CRS) is an interdependent involvement of the heart and the kidney that leads to high morbidity, recurrent readmissions and grave prognosis.
Anand Bhutada, Abhijit Choudhary, Atul Kapse, Vinayak Patki   +3 more
doaj   +1 more source

Role of RIPK1/RIPK3/MLKL signalling pathway in sepsis‐associated acute kidney injury

Experimental Physiology, EarlyView.
Abstract Sepsis‐associated acute kidney injury (SA‐AKI) is a common clinical syndrome in critically ill patients, and its high mortality rate is closely related to complex pathological mechanisms. Existing studies have shown that the pathophysiological process of SA‐AKI involves complex multi‐mechanism interactions, including an uncontrolled systemic ...
Huijun Yin, Jingyi Wang, Huirong Han
wiley   +1 more source

Oral Celastrol Micelles Forming High‐Density Lipoprotein Corona Targeting Hepatocytes for MASLD Treatment

Advanced Science, Volume 12, Issue 45, December 4, 2025.
Upon oral administration, OPDEA‐PCL/CEL micelles passed through the stomach acid intact, then quickly penetrated the intestinal mucus and transported into circulation, where they captured HDL to form a protein corona and target hepatocyte SR‐B1 receptors, inducing endocytosis.
Chang Xu, Haoru Zhu, Kai Wang, Haitao Hu, Xuyong Wei, Dongdong Xu, Jing Zhang, Yanpeng Liu, Jun Chen, Youqing Shen, Nasha Qiu, Xiao Xu   +11 more
wiley   +1 more source

Hepatorenal Syndrome: Diagnosis and Treatment – newsreel –

Romanian Journal of Internal Medicine, 2016
Hepatorenal syndrome (HRS) is defined as renal failure that occurs in the presence of severe acute or chronic liver disease in the absence of underlying renal pathology.
Enescu Aurelia, Petrescu F., Mitruţ P., Petrescu Ileana Octavia, Pădureanu V., Enescu Anca Ştefania   +5 more
doaj   +1 more source

Predictive factors of neurological complications and one-month mortality after liver transplantation. [PDF]

, 2014
BackgroundNeurological complications are common after orthotopic liver transplantation (OLT). We aimed to characterize the risk factors associated with neurological complications and mortality among patients who underwent OLT in the post-model for end ...
Akhtar, Shahrzad, DiNorcia, Joseph, Fu, Katherine A, Kalayjian, Laura A, Sanossian, Nerses, Sher, Linda, Velani, Shamsha A   +6 more
core   +1 more source

Nonalcoholic Fatty Liver Disease Exacerbates the Advancement of Renal Fibrosis by Modulating Renal CCR2+PIRB+ Macrophages Through the ANGPTL8/PIRB/ALOX5AP Axis

Advanced Science, Volume 12, Issue 46, December 11, 2025.
The ANGPTL8/PIRB/ALOX5AP axis mediates liver‐kidney crosstalk. Hepatocytes secrete ANGPTL8, which binds to CCR2+PIRB+ macrophages in the kidneys, affecting the expression of ALOX5AP and enhancing the activation of these macrophages. Activated cells produce TGF‐β, IL‐6, and IL‐23, driving Th17 activation and promote the formation of myofibroblasts ...
Shuqi Wei, Diwen Shou, Siyuan Huang, Yingsi Wang, Quanzhen Liu, Jinfa Liu, Xiaoyu Lv, Yuyi Zeng, Liting Wei, Han Lin, Jiechuan Chen, Yangxiao Chen, Haoyu Zhong, Yanqing Zhou, Wen Ma, Li Wang, Guojun Qian, Jing Guo, Donglin Sun   +18 more
wiley   +1 more source

Hepatorenal Syndrome in the Emergency Department: A Case Report

International Journal of Medical Students, 2015
Background: Hepatorenal syndrome is a condition where there is functional renal failure in a background of liver disease. It is relatively common in patients with liver cirrhosis and is associated with a high mortality rate if untreated. Results: This
Win Jim Tan, Mohan Tiruchittampalam
doaj  

Paraquat Poisoning: A Case of Daisley–Barton Syndrome and Hepatorenal Failure

Clinical Case Reports, Volume 13, Issue 12, December 2025.
ABSTRACT Paraquat (PQ) is a highly toxic herbicide that causes severe poisoning. It mainly affects the lungs, liver, and kidneys. When ingested intentionally, it has a high mortality rate due to the absence of an effective antidote. We present a rare case of a 35‐year‐old female with deliberate ingestion of paraquat for a suicide attempt.
Ali Gohar, Muhammad Husnain Ahmad, Asad Ullah Mahmood, Usama Naghman, Abdul Rehman Shahid Khan, Hamza Zaheer, Hamza Hafeez Farooqi, Marium Nadeem Khan, Masab Ali   +8 more
wiley   +1 more source

Initial serum sodium concentration determines the decrease in sodium level after terlipressin administration in patients with liver cirrhosis [PDF]

, 2013
BACKGROUND: Terlipressin, as a prodrug of vasopressin, has agonistic effects on the V1 receptor and partial agonistic effects on renal vasopressin V2 receptors. However, its effects on serum sodium concentration are controversial.
Dae-Hong Jeon, Dong Park, Eun Bae, Ha Jang, Hyun Cho, Kyungo Hwang, Se-Ho Chang, Yeo-Jin Kang   +7 more
core   +1 more source

Organ Crosstalk During Injury: Mechanisms of Lung–Kidney Interaction in Critical Illness

Comprehensive Physiology, Volume 15, Issue 6, December 2025.
Crosstalk between the lungs and kidneys may propagate multiorgan injury in critically ill patients. This review examines evidence of crosstalk between the lungs and kidneys after injury, focusing on translational and mechanistic studies. Pathophysiology and animal models of acute kidney injury (AKI) and acute respiratory distress syndrome (ARDS) are ...
Kathryn M. Sullivan, Kathleen D. Liu, Michael A. Matthay   +2 more
wiley   +1 more source