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Expert Opinion on Pharmacotherapy, 2011
Hepatorenal syndrome (HRS) is a functional renal failure that often occurs in patients with cirrhosis and ascites. Two different types of HRS have been described. Type 1 HRS develops as a consequence of a severe reduction of effective circulating volume due to both an extreme splanchnic arterial vasodilatation and a reduction of cardiac output.
ANGELI, PAOLO +3 more
+7 more sources
Hepatorenal syndrome (HRS) is a functional renal failure that often occurs in patients with cirrhosis and ascites. Two different types of HRS have been described. Type 1 HRS develops as a consequence of a severe reduction of effective circulating volume due to both an extreme splanchnic arterial vasodilatation and a reduction of cardiac output.
ANGELI, PAOLO +3 more
+7 more sources
Critical Care Clinics, 2021
Development of acute kidney injury in patients with chronic liver disease is common and portends a poor prognosis. Diagnosis remains challenging, as traditional markers, such as serum creatinine, are not reliable. Recent development of novel biomarkers may assist with this.
Saro, Khemichian +4 more
openaire +2 more sources
Development of acute kidney injury in patients with chronic liver disease is common and portends a poor prognosis. Diagnosis remains challenging, as traditional markers, such as serum creatinine, are not reliable. Recent development of novel biomarkers may assist with this.
Saro, Khemichian +4 more
openaire +2 more sources
Clinics in Liver Disease, 2000
Hepatorenal syndrome is a functional renal failure that occurs in cirrhotic patients with advanced liver disease and ascites. The diagnostic criteria and clinical types of this syndrome have recently been revised. Hepatorenal syndrome is caused by marked hypoperfusion of the kidney as the result of renal vasoconstriction, which is thought to be the ...
R, Bataller +3 more
+7 more sources
Hepatorenal syndrome is a functional renal failure that occurs in cirrhotic patients with advanced liver disease and ascites. The diagnostic criteria and clinical types of this syndrome have recently been revised. Hepatorenal syndrome is caused by marked hypoperfusion of the kidney as the result of renal vasoconstriction, which is thought to be the ...
R, Bataller +3 more
+7 more sources
Nature Reviews Disease Primers, 2018
Hepatorenal syndrome (HRS) is a form of kidney function impairment that characteristically occurs in cirrhosis. Recent changes in terminology have led to acute HRS being referred to as acute kidney injury (AKI)-HRS and chronic HRS as chronic kidney disease (CKD)-HRS.
Pere, Ginès +5 more
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Hepatorenal syndrome (HRS) is a form of kidney function impairment that characteristically occurs in cirrhosis. Recent changes in terminology have led to acute HRS being referred to as acute kidney injury (AKI)-HRS and chronic HRS as chronic kidney disease (CKD)-HRS.
Pere, Ginès +5 more
openaire +4 more sources
Journal of Gastroenterology and Hepatology, 2002
The hepatorenal syndrome is defined as functional renal failure in advanced chronic or acute liver disease with portal hypertension. Morphologic abnormalities of the kidneys are frequently absent and tubular function is preserved. Patients with the hepatorenal syndrome are characterized by progressive splanchnic and systemic vasodilation and decreased ...
Ludwig, Kramer, Walter H, Hörl
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The hepatorenal syndrome is defined as functional renal failure in advanced chronic or acute liver disease with portal hypertension. Morphologic abnormalities of the kidneys are frequently absent and tubular function is preserved. Patients with the hepatorenal syndrome are characterized by progressive splanchnic and systemic vasodilation and decreased ...
Ludwig, Kramer, Walter H, Hörl
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Seminars in Liver Disease, 1997
Hepatorenal syndrome is a common complication in patients with advanced cirrhosis and ascites characterized not only by renal failure but also by marked alterations in systemic hemodynamics and vasoactive systems. Renal failure is due to a marked hypoperfusion of the kidney secondary to renal vasoconstriction.
R, Bataller +3 more
openaire +2 more sources
Hepatorenal syndrome is a common complication in patients with advanced cirrhosis and ascites characterized not only by renal failure but also by marked alterations in systemic hemodynamics and vasoactive systems. Renal failure is due to a marked hypoperfusion of the kidney secondary to renal vasoconstriction.
R, Bataller +3 more
openaire +2 more sources
The Lancet, 1977
The term "hepatorenal syndrome" is used to bring together a variety of syndromes whose common feature is liver and kidney parenchymal distress. For this reason, its use has been questioned by many workers. A subdivision into acute and chronic forms is proposed and emphasis is placed on the common physiopathogenetic processes, together with the notable ...
M E, Allison +3 more
openaire +4 more sources
The term "hepatorenal syndrome" is used to bring together a variety of syndromes whose common feature is liver and kidney parenchymal distress. For this reason, its use has been questioned by many workers. A subdivision into acute and chronic forms is proposed and emphasis is placed on the common physiopathogenetic processes, together with the notable ...
M E, Allison +3 more
openaire +4 more sources
Current Treatment Options in Gastroenterology, 2005
Hepatorenal syndrome (HRS) is defined as functional renal failure that develops in patients with advanced liver disease. HRS may be either slowly or rapidly progressive (type I and II HRS, respectively). Untreated HRS carries a high mortality. Liver transplantation is the best available treatment for HRS. However, all patients with HRS are not suitable
Bimaljit Singh, Sandhu, Arun J, Sanyal
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Hepatorenal syndrome (HRS) is defined as functional renal failure that develops in patients with advanced liver disease. HRS may be either slowly or rapidly progressive (type I and II HRS, respectively). Untreated HRS carries a high mortality. Liver transplantation is the best available treatment for HRS. However, all patients with HRS are not suitable
Bimaljit Singh, Sandhu, Arun J, Sanyal
+7 more sources
AACN Advanced Critical Care, 1992
The exact physiologic mechanism of the hepatorenal syndrome remains unclear; however, it always develops in the presence of liver failure. A number of theories have been postulated to explain the syndrome, which are discussed in this review. None of the proposed theories is able to explain the syndrome completely, and continued research is necessary ...
C, Mudge, L, Carlson
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The exact physiologic mechanism of the hepatorenal syndrome remains unclear; however, it always develops in the presence of liver failure. A number of theories have been postulated to explain the syndrome, which are discussed in this review. None of the proposed theories is able to explain the syndrome completely, and continued research is necessary ...
C, Mudge, L, Carlson
openaire +2 more sources
The International Journal of Biochemistry & Cell Biology, 2004
Hepatorenal syndrome (HRS) is a major complication of patients with cirrhosis, with the annual incidence in patients with ascites being approximately 8% []. This syndrome develops in the latest phase of the disease and there is now evidence that it is an important determinant of patient survival.
Mónica, Guevara, Juan, Rodés
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Hepatorenal syndrome (HRS) is a major complication of patients with cirrhosis, with the annual incidence in patients with ascites being approximately 8% []. This syndrome develops in the latest phase of the disease and there is now evidence that it is an important determinant of patient survival.
Mónica, Guevara, Juan, Rodés
openaire +4 more sources