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Hepatorenal Syndrome

Expert Opinion on Pharmacotherapy, 2011
Hepatorenal syndrome (HRS) is a functional renal failure that often occurs in patients with cirrhosis and ascites. Two different types of HRS have been described. Type 1 HRS develops as a consequence of a severe reduction of effective circulating volume due to both an extreme splanchnic arterial vasodilatation and a reduction of cardiac output.
ANGELI, PAOLO   +3 more
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HEPATORENAL SYNDROME

Clinics in Liver Disease, 2000
Hepatorenal syndrome is a functional renal failure that occurs in cirrhotic patients with advanced liver disease and ascites. The diagnostic criteria and clinical types of this syndrome have recently been revised. Hepatorenal syndrome is caused by marked hypoperfusion of the kidney as the result of renal vasoconstriction, which is thought to be the ...
R, Bataller   +3 more
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Hepatorenal syndrome

Journal of Gastroenterology and Hepatology, 2002
The hepatorenal syndrome is defined as functional renal failure in advanced chronic or acute liver disease with portal hypertension. Morphologic abnormalities of the kidneys are frequently absent and tubular function is preserved. Patients with the hepatorenal syndrome are characterized by progressive splanchnic and systemic vasodilation and decreased ...
Ludwig, Kramer, Walter H, Hörl
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Hepatorenal Syndrome

Clinics in Liver Disease, 2006
Among the many causes of renal failure in patients who have advanced liver disease, functional renal failure occurring in the absence of parenchymal kidney disease, better known as hepatorenal syndrome (HRS), is the most frequent cause of renal dysfunction in patients who have cirrhosis.
Andrés, Cárdenas, Pere, Gines
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Hepatorenal Syndrome

Seminars in Liver Disease, 1997
Hepatorenal syndrome is a common complication in patients with advanced cirrhosis and ascites characterized not only by renal failure but also by marked alterations in systemic hemodynamics and vasoactive systems. Renal failure is due to a marked hypoperfusion of the kidney secondary to renal vasoconstriction.
R, Bataller   +3 more
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The Hepatorenal Syndrome

Clinical Science, 1997
1. The hepatorenal syndrome is the development of renal failure in patients with severe liver disease in the absence of any identifiable renal pathology. 2. Decreased glomerular filtration is caused by a reduction in both renal blood flow and the renal filtration fraction.
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Hepatorenal syndrome

Current Treatment Options in Gastroenterology, 2005
Hepatorenal syndrome (HRS) is defined as functional renal failure that develops in patients with advanced liver disease. HRS may be either slowly or rapidly progressive (type I and II HRS, respectively). Untreated HRS carries a high mortality. Liver transplantation is the best available treatment for HRS. However, all patients with HRS are not suitable
Bimaljit Singh, Sandhu, Arun J, Sanyal
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Hepatorenal Syndrome

AACN Advanced Critical Care, 1992
The exact physiologic mechanism of the hepatorenal syndrome remains unclear; however, it always develops in the presence of liver failure. A number of theories have been postulated to explain the syndrome, which are discussed in this review. None of the proposed theories is able to explain the syndrome completely, and continued research is necessary ...
C, Mudge, L, Carlson
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The Hepatorenal Syndrome

Medical Clinics of North America, 1990
HRS occurs frequently in patients with advanced cirrhosis of the liver and fulminant hepatitis. The pathogenesis of HRS is not clearly understood; reduced effective plasma volume and intense renal cortical vasoconstriction seem to have important roles.
R C, Punukollu, N, Gopalswamy
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Hepatorenal syndrome

The International Journal of Biochemistry & Cell Biology, 2004
Hepatorenal syndrome (HRS) is a major complication of patients with cirrhosis, with the annual incidence in patients with ascites being approximately 8% []. This syndrome develops in the latest phase of the disease and there is now evidence that it is an important determinant of patient survival.
Mónica, Guevara, Juan, Rodés
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