Hepatosplenomegaly and Pernicious Anaemia [PDF]
Sir, Pernicious anaemia (PA) is the end stage of atrophic gastritis which results in the loss of parietal cells in the fundus and body of the stomach. Loss of parietal cells is associated with the failure of intrinsic factor production and results in vitamin B12 deficiency and megaloblastic anaemia.
Turgay Ulas +4 more
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The Spectrum of Clinical Manifestations of Serious Human Parvovirus B19 Infection in Children without any Underlying Diseases- A Case Series [PDF]
Human Parvovirus B19 causes mild to life-threatening illnesses, especially in immunosuppressed individuals. In the immunocompetent individuals, the severe spectrum of clinical manifestations of the virus infection is not widely known.
Subham Bhattacharya +2 more
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Hemophagocytic Lymphohistiocytosis Presenting as Neonatal Cholestasis: A Case Report [PDF]
Background:. Hemophagocytic lymphohistosis (HLH) is a life-threatening clinical syndrome that involves liver dysfunction and can range from mild dysfunction to severe fulminant insufficiency.
Raheleh Faramarzi +4 more
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Hypercalcaemia: An Extremely Rare Presentation of Hepatosplenic T-Cell Lymphoma
Hypercalcaemia is a frequent finding in malignancies including lymphomas. However, there are no reports of hypercalcaemia in hepatosplenic T-cell lymphoma (HSTCL). HSTCL is a rare and aggressive neoplasm which is usually difficult to diagnose. We present
Sara Almeida Ramalho +6 more
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Brucellosis Infection- A Leukaemia Mimic [PDF]
Dear Editor, Brucellosis is multi-systemic infection with varied clinical presentation. Hematological manifestation of brucella includes, anaemia, thrombocytopenia, and pancytopenia with hepatosplenomegaly, lymphadenopathy which can be misdiagnosed as ...
Santosh Govind Rathod, Sauliha Yaseen
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Autosomal Recessive Polycystic Kidney Disease in a Child Complicated by Autoimmune Hemolytic Anemia: A Case Report [PDF]
Autosomal recessive polycystic kidney disease (ARPKD) is a rare genetic disorder that presents as an isolated polycystic renal disease in childhood, or associated with congenital hepatic fibrosis and/or Caroli disease.
Magd A. Kotb +7 more
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Combined Hereditary Spherocytosis and β-thalassemia trait: A Rare Co-existence [PDF]
Haemoglobinopathies are the commonest haemolytic disorders, prevalent in India and form a major bulk of patients in most of the haematology outpatient clinics.
Hanaganahalli Basavaiah Sridevi +4 more
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Hepatocyte-derived IL-10 plays a crucial role in attenuating pathogenicity during the chronic phase of T. congolense infection [PDF]
Bovine African Trypanosomosis is an infectious parasitic disease affecting livestock productivity and thereby impairing the economic development of Sub-Saharan Africa. The most important trypanosome species implicated is T.
Brys, Lea +6 more
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POEMS Syndrome with Biclonal Gammopathy: A Rare Association [PDF]
Polyneuropathy, Organomegaly, Endocrinopathy, M protein and Skin changes (POEMS) syndrome is rare plasma cell dyscrasia with multisystem involvement. The name comes from the five characteristic features: Polyneuropathy, organomegaly, endocrinopathy, M ...
DIBYENDU DE +2 more
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Letter to the Editor: Coexistence of Autoimmune Lymphoproliferative Syndrome and Familial Mediterranean Fever [PDF]
Autoimmune lymphoproliferative syndrome (ALPS) is a rare inherited disorder of apoptosis, most commonly due to mutations in the FAS (TNFRSF6) gene. ALPS caused by defective lymphocyte homeostasis is characterized by non-malignant lymphoproliferation that
Sultan Aydin Koker +5 more
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