Results 231 to 240 of about 4,621,966 (335)

Introduction of Nanotechnology in Herbal Drugs and Nutraceutical: A Review

, 2016
S. Gopi, A. Amalraj, J. Haponiuk, Sabu Thomas   +3 more
semanticscholar   +1 more source

A Combined Colon Organoid‐Sensory Neuron Model Reveals Epithelial Contribution to Moringin Efficacy Against Painful Inflammatory Bowel Disease

Phytotherapy Research, EarlyView.
Experimental workflow and main findings of the study. ABSTRACT Visceral pain is a major symptom of inflammatory bowel diseases (IBDs), requiring effective treatment strategies. Gut epithelium, beyond maintaining barrier integrity and microbiota homeostasis, modulates neurosensorial circuitries, influencing visceral sensitivity.
Francesco Margiotta, Elena Lucarini, Alessandra Toti, Maria Giovanna Cataldi, Clara Ciampi, Gina Rosalinda De Nicola, Lorenzo Di Cesare Mannelli, Carla Ghelardini   +7 more
wiley   +1 more source

Pedunculoside Inhibits Hepatocellular Carcinoma Progression by Activating the MAPK Signaling Pathway Through Targeting and Suppressing CDK4

Phytotherapy Research, EarlyView.
Pedunculoside targets and suppresses CDK4; consequently, it activates the MAPK pathway and inhibits hepatocellular carcinoma progression. ABSTRACT Hepatocellular carcinoma (HCC) remains a major challenge in cancer prevention and treatment, highlighting the urgent need for effective and low‐toxicity anti‐HCC therapies. Recently, CDK4‐targeted inhibitors
Yang Zhou, Jingyun Chi, Yuan Ding, Zhidi Zhang, Rui Liang, Tianhao Wang, Yan Jiang, Rujun Song, Huazhou Fu, Xizhen Zhou   +9 more
wiley   +1 more source

Safety Evaluation of an Aqueous Root and Leaf Extract of Ashwagandha (Withania somnifera)

Phytotherapy Research, EarlyView.
Sensoril, an aqueous root and leaf extract of ashwagandha showed no evidence of mutagenicity in the in vitro Ames assay, was negative in the in vitro micronucleus, in vivo mammalian bone marrow chromosome aberration assays, and was well tolerated in the rat at up to 4000 mg/kg BW/day when administered orally for a period of 90 days. The data from these
Mukesh Summan, Candace L. Doepker, Gregory P. Brorby   +2 more
wiley   +1 more source

Safety of 8‐Week Administration With Ashwagandha (Withania somnifera) Root Extract in Adults With Stress and Anxiety: Findings From a Prospective, Randomized, Multi‐Center, Double‐Blinded, Placebo‐Controlled Study

Phytotherapy Research, EarlyView.
ABSTRACT Ashwagandha (Withania somnifera) has been recognized for enhancing physical strength, mental well‐being, and overall vitality. Despite its long‐standing use across generations, some clinical reports have noted occasional adverse events. This study compared the safety and tolerability of Ashwagandha Root Extract (ARE) in healthy adults.
Ketan Pakhale, Jaising Salve, John Ademola, Jose Parraca, Deepak Langade   +4 more
wiley   +1 more source

Microglial Activation Under Hypoxic Conditions in Early Alzheimer's Disease: Can Natural SIRT1 Activators Be Therapeutic Allies in the Inflammation–Energy Axis?

Phytotherapy Research, EarlyView.
ABSTRACT Alzheimer's disease (AD) is a progressive neurodegenerative condition characterized by a preclinical stage that typically lasts for decades. Early on during this time, microglia react to pathological changes and become protective and even transiently delay neurodegeneration.
Sara Merlo, Cristiana Lucia Rita Lipari, Aurora Patti, Maria Angela Sortino   +3 more
wiley   +1 more source

Trends and Patterns for the Use of Herbal Medicinal Products for Gynaecological Ailments

Phytotherapy Research, EarlyView.
ABSTRACT Most Germans consider herbal medicinal products (HMPs) to be an important supplement to conventional medicine. Despite existing clinical evidence for safety and efficacy, they are still not sufficiently integrated into drug therapy of gynaecological complaints in everyday practice.
Alexandra Drebka, Annika J. Scholl, Teresa Ochs, Olaf Kelber, Ralph Mösges, Beatrice E. Bachmeier   +5 more
wiley   +1 more source

Efficacy of Plant‐Derived Therapies for Primary Dysmenorrhea: A Systematic Review and Meta‐Analysis of Randomized Controlled Trials

Phytotherapy Research, EarlyView.
ABSTRACT Primary dysmenorrhea is defined as recurrent, cramp‐like lower abdominal pain occurring during menstruation in the absence of underlying pelvic pathology. A significant proportion of the population opts for natural plant‐based remedies due to their perceived lower incidence of adverse effects.
Lifei Wu, Inmaculada Xu Lou, Zhenting Hu, Gan Wang, Sammit Vishram Deshpande, Rocío Cáceres‐Matos   +5 more
wiley   +1 more source

Constructing Difference: Maternal Boundary‐Work in Science‐Based and Natural Mom Groups on Facebook

Symbolic Interaction, EarlyView.
Boundary‐work describes the activities of social groups as they seek to differentiate themselves from others to establish credibility, authority, or to protect their interests. While a growing body of literature explores occupational boundary‐work in health care, limited research has focused on how lay actors practice boundary‐work online.
Darryn DiFrancesco
wiley   +1 more source

National Seminar on "Regulatory and Quality Aspects of Herbal Drugs and Botanicals".

J Pharm Bioallied Sci, 2015
Ahmad S.
europepmc   +1 more source