Results 91 to 100 of about 2,398,099 (295)

Effect of carbamazepine on the pharmacokinetics of vepdegestrant, a PROteolysis TArgeting Chimera estrogen receptor degrader, in healthy adults

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aim To evaluate the effects of carbamazepine, a strong cytochrome P450 (CYP)3A4 inducer, on the pharmacokinetics and safety of vepdegestrant, a PROteolysis TArgeting Chimera estrogen receptor degrader. Methods This was a phase 1, open‐label, fixed‐sequence, two‐period study in healthy adult participants.
Hechuan Wang   +7 more
wiley   +1 more source

The use of herbal medicines among chronic disease patients in Thailand: a cross-sectional survey

open access: yesJournal of Multidisciplinary Healthcare, 2019
Karl Peltzer,1 Supa Pengpid1,21Deputy Vice Chancellor Research and Innovation Office, North West University, Potchefstroom, South Africa; 2Asean Institute for Health Development, Mahidol University, Salaya, Phutthamonthon, Nakhonpathom ...
Peltzer K, Pengpid S
doaj  

KNOWLEDGE AND BELIEFS TOWARD THE USE OF HERBAL MEDICINE AMONG IRAQI MEDICAL STUDENTS

open access: yesGlobal Journal of Public Health Medicine
Introduction: Herbal medicine use among medical students is common worldwide, driven by influences such as societal or cultural norms, accessibility, and interest in complementary and alternative medicine. This trend highlights the importance of medical
Fakat Alola Ghanim Jawad   +1 more
doaj   +1 more source

Analysis of interstitial lung disease in pharmacovigilance databases: Coding challenges and interpretation biases—An update

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aim Clinically, interstitial lung disease (ILD) is a heterogeneous group of respiratory disorders. Due to their low incidence, pharmacovigilance database analysis is useful to detect them. Precise diagnosis is challenging as well as coding in these databases. Query criteria are among the key elements for a good signal detection.
Romane Freppel   +4 more
wiley   +1 more source

Safety of Postpartum Herbal Medicine in Primary Care Korean Medicine Clinics: Protocol for a Prospective, Multicenter, Registry-Based Observational Study

open access: yesJMIR Research Protocols
BackgroundPostpartum conditions significantly affect maternal and infant health. In South Korea, herbal medicine is commonly used for postpartum care in Korean medicine, but safety data remain limited.
Anna Kim   +7 more
doaj   +1 more source

Deciphering the catalytic and pharmacological mechanisms of Coptis chinensis herbzymes to renovate intestinal microenvironment for colitis alleviation

open access: yesBMEMat, EarlyView.
The synthesized CCzymes possess both antioxidant enzyme activity and pharmacological properties inherent to Coptis chinensis. By their antioxidant enzyme activity, CCzymes can attenuate oxidative stress within the inflammatory region of ulcerative colitis (UC), while their pharmacological activity acts on macrophage polarization and the intestinal ...
Zhichao Deng   +10 more
wiley   +1 more source

New Insights for Cellular and Molecular Mechanisms of Aging and Aging-Related Diseases: Herbal Medicine as Potential Therapeutic Approach

open access: yesOxidative Medicine and Cellular Longevity, 2019
Aging is a progressive disease affecting around 900 million people worldwide, and in recent years, the mechanism of aging and aging-related diseases has been well studied. Treatments for aging-related diseases have also made progress.
Yanfei Liu   +3 more
semanticscholar   +1 more source

The ageing holobiont: crosstalk between telomere dynamics, oxidative stress and the gut microbiome

open access: yesBiological Reviews, EarlyView.
ABSTRACT The gut tissue is at the frontline of early onset of ageing. It exhibits high cell turnover rates and rapid telomere shortening, which can have systemic effects on the developing or senescing organism. We conducted a literature review of studies on the crosstalk between telomere length dynamics, telomerase activity, oxidative stress, and gut ...
Michael L. Pepke   +2 more
wiley   +1 more source

Rising Strong: Cultivating Resilience in Edible City Entrepreneurship. Insights Into the Landscape of Urban Food Initiatives

open access: yesBusiness Strategy and the Environment, EarlyView.
ABSTRACT In response to growing global challenges, this study explores how social entrepreneurship within the Edible City movement contributes to building resilient, sustainable, and equitable urban food systems. Drawing on semistructured interviews with over 70 stakeholders across five cities—Berlin, Andernach, Oslo, Rotterdam, and Havana—we ...
Ina Säumel   +6 more
wiley   +1 more source

Apoptosis Induction of Fibroblast-Like Synoviocytes Is an Important Molecular-Mechanism for Herbal Medicine along with its Active Components in Treating Rheumatoid Arthritis

open access: yesBiomolecules, 2019
Rheumatoid arthritis (RA) is a known chronic autoimmune disease can cause joint deformity and even loss of joint function. Fibroblast-like synoviocytes (FLS), one of the main cell types in synovial tissues of RA patients, are key effector cells in the ...
Qing Zhang   +7 more
semanticscholar   +1 more source

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