Results 171 to 180 of about 315,917 (337)

Isorhamnetin Alleviates Renal Fibrosis Induced by Renal Tubular Epithelial Cell Senescence Via Inhibition of the IL‐6/IL‐6R Signaling Pathway

open access: yesiMetaMed, EarlyView.
IL‐6 from RTECs upregulates TGF‐β in macrophages, promoting fibroblast transdifferentiation. Isorhamnetin inhibits this effect. ABSTRACT Chronic kidney disease (CKD) is a major global health issue. Kidney fibrosis is a key mechanism leading to end‐stage renal disease.
Weifei Liang   +8 more
wiley   +1 more source

Discovery of Embelin as a Cell-Permeable, Small-Molecular Weight Inhibitor of XIAP through Structure-Based Computational Screening of a Traditional Herbal Medicine Three-Dimensional Structure Database

open access: green, 2004
Zaneta Nikolovska‐Coleska   +12 more
openalex   +1 more source

“Not a Single Leaf Is Meant to be Taken With You”: Conservation Motivations and Belief Systems in a Khasi Sacred Landscape of Meghalaya, India “一片叶子都不许带走”:印度梅加拉亚邦卡西族神圣景观中的保护动机与信仰体系

open access: yesIntegrative Conservation, EarlyView.
This study examines the Mawphlang Sacred Forest in Meghalaya as a culturally embedded model of community‐led conservation. Drawing on qualitative fieldwork, it highlights how spiritual reverence, sacred taboos, and ancestral authority shape ecological stewardship, complementing formal governance systems.
Mrinal Saikia
wiley   +1 more source

Schisantherin A: Remodeling Gut Microbiota to Activate the Gut–Immune–Neural–Adipose Axis for Thermogenesis

open access: yesiNew Medicine, EarlyView.
ABSTRACT The global obesity epidemic necessitates safe and effective strategies to enhance energy expenditure. Schisantherin A (Sin A), a lignan derived from Schisandra chinensis, has demonstrated metabolic benefits, yet its systemic mechanism remains unclear.
Ling Yin
wiley   +1 more source

Plant‐derived extracellular vesicle‐like particles as novel osteoanabolic agents: Activating bone morphogenetic protein 2/Smads signaling axis for bone regeneration in postmenopausal osteoporosis

open access: yesInterdisciplinary Medicine, EarlyView.
Illustration depicting the isolation of Dipsaci Radix derived extracellular vesicle‐like particles and their function in alleviating osteoporosis. (A) Extraction and characterization detection process of extracellular vesicle‐like particles derived from Dipsaci Radix roots. (B) Cell experiments in vitro, Dipsaci Radix derived extracellular vesicle‐like
Qing Zhao   +12 more
wiley   +1 more source

Evidence-based production framework for herbal medicine regulation in Indonesia. [PDF]

open access: yesFront Pharmacol
Kashuri M   +4 more
europepmc   +1 more source

Interpretable machine learning enables early and accurate detection of drug‐induced liver injury: A multicenter study with real‐world clinical translation

open access: yesInterdisciplinary Medicine, EarlyView.
This study develops an interpretable gradient‐boosting model that accurately identifies drug‐induced liver injury (DILI) using routine laboratory data. The model explains key clinical features through SHapley Additive exPlanations analysis and detects DILI earlier than expert evaluation, offering a transparent and practical tool for precision ...
Jingyi Ling   +13 more
wiley   +1 more source

Effectiveness of Herbal and Allopathic Medicines in Treating Frostbite

open access: gold
Madhu Priya   +6 more
openalex   +1 more source

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