Results 181 to 190 of about 2,314,937 (397)

Astragali Radix (Huangqi): A promising edible immunomodulatory herbal medicine.

open access: yesJournal of Ethnopharmacology, 2020
Zhejie Chen   +10 more
semanticscholar   +1 more source

Discovery of a Phenylalanine‐derived Natural Compound as a Potential Dual Inhibitor of MDM2 and MDMX

open access: yesChemMedChem, Accepted Article.
Dual inhibition of the negative p53 regulators MDM2 and MDMX has emerged as an effective strategy in p53‐based anticancer therapy. However, dual inhibitors are limited, and many inhibitors exhibit poor pharmacokinetic properties and fast dissociation kinetics.
JA YOUNG CHO   +5 more
wiley   +1 more source

Evaluation of Potential Effects of CYP3A Inhibition and CYP3A Induction on the Pharmacokinetics of Fruquintinib in Healthy Subjects

open access: yesClinical Pharmacology in Drug Development, EarlyView.
Abstract Cytochrome P450 (CYP) 3A plays a significant role in fruquintinib metabolism in vitro. This 2‐part, 2‐period fixed‐sequence study investigated the impact of CYP3A inhibition (itraconazole) and CYP3A induction (rifampin) on the pharmacokinetics (PK) of fruquintinib and M11, its main metabolite.
Martha Gonzalez   +5 more
wiley   +1 more source

A case of drug-induced allergic hepatitis by herbal medicine.

open access: bronze, 1985
Y Mizoguchi   +8 more
openalex   +2 more sources

Pharmacokinetics, Safety, and Tolerability of Single‐Dose Dazukibart in Healthy Adults in China and Japan: Results From 2 Randomized, Double‐Blind, Phase 1 Studies

open access: yesClinical Pharmacology in Drug Development, EarlyView.
Abstract Dazukibart is a humanized monoclonal antibody selectively targeting interferon‐β. The pharmacokinetics (PK), safety, tolerability, and immunogenicity of dazukibart were evaluated in 2 double‐blind, randomized, placebo‐controlled, single‐dose, Phase 1 studies in healthy adults in China (Study 1: N = 18; dazukibart 900 mg = 15; placebo = 3) and ...
Naihan Chen   +10 more
wiley   +1 more source

Herbal medicine: Knowledge, attitude and practice in Tehran

open access: yesJournal of Medicinal Plants, 2005
Background: Herbal medicine is one of complementary medicine (CAM) approaches that refer to a group of therapeutic and diagnostic disciplines that exists largely outside the institutions where conventional health care is taught and provided for treating ...
J Sadighi, F Maftoon, SA Ziai
doaj  

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