Bazi Bushen Capsule restores fertility by targeting mitochondrial health in aging endometrium
Bazi Bushen Capsule (BZBS) mitigates age‐related endometrial dysfunction by activating AMPK − SIRT3 signaling. Luteolin, a key bioactive component, restores mitochondrial homeostasis via PINK1/Parkin−mediated mitophagy and Drp1 inhibition, improving endometrial function and fertility potential.
Shangqi Li +13 more
wiley +1 more source
Phosphorus Limitation Governs N:P Stoichiometry in Semi-Arid Shrublands: Evidence From Organ, Plant and Community Scales. [PDF]
Li Y +5 more
europepmc +1 more source
Natural products and traditional Chinese medicine target metabolic pathways underlying right ventricular dysfunction in pulmonary arterial hypertension. Integrating multi‐omics, artificial intelligence, and systems biology may enable precision cardiometabolic therapies to restore right ventricular metabolism and improve clinical outcomes.
Yihao Wu, Zhehui Tang, Hongwei Yao
wiley +1 more source
Anti-Obesogenic Effects of Culinary Herbs Through Modulation of Inflammation and Metabolic Pathways. [PDF]
Winiarska A +6 more
europepmc +1 more source
PD alleviates APAP‐induced ALI by inhibiting the NLRP3 inflammasome signaling pathway. C/EBPβ is identified as a direct target via multimethod validation. PD promotes the deacetylation of C/EBPβ via Sirt1. The Sirt1/C/EBPβ/NLRP3 signaling axis is defined for PD's hepatoprotective effect.
Tian‐Yu Yang +6 more
wiley +1 more source
Effects of Fermented Compound Chinese Herbal Feed on Gut Microbiota, Immune Response, and Disease Resistance in Chinese Soft-Shelled Turtle (<i>Pelodiscus sinensis</i>). [PDF]
Lu C +7 more
europepmc +1 more source
MBB modulates the TNBC tumor microenvironment by targeting TAM/CXCL1 and facilitates anti‐PD‐L1 therapy by disrupting CAF barriers via its photothermal effect. This combined strategy subsequently enhances the efficacy of PD‐L1 mAb and suppresses TNBC progression, metastasis, and recurrence.
Bo Pan +12 more
wiley +1 more source
Is beta diversity higher in seed plants with larger body sizes? [PDF]
Qian H.
europepmc +1 more source
The regulation of stem cell fate and its application in neural regeneration
Regulating stem cell fate is crucial for neural regeneration. This review summarizes key physical, biological, and chemical strategies and their applications in repairing nerve injuries, providing new insights for regenerative medicine. Abstract Regulating the fate of stem cells (SCs) is a key technical problem in the field of regenerative medicine and
Yuexin He +3 more
wiley +1 more source
Cooperative extension and academic departments partnership: Translating nutrition science messages to diverse audiences. [PDF]
Lawler O +6 more
europepmc +1 more source

