Results 101 to 110 of about 269,395 (254)

Molecular Dynamics‐Guided Sterol Engineering of mRNA‐Lipid Nanoparticles Reprograms Biodistribution and Enhances Spleen‐Selective Immunity

open access: yesAdvanced Science, EarlyView.
Sterol engineering enables precise control of mRNA lipid nanoparticles by tuning membrane organization. Replacing cholesterol with bile acid‐derived sterols redirects protein expression from the liver to the spleen. Notably, CA‐20 LNP enhances antigen‐specific immune responses while exhibiting a favorable safety profile, highlighting sterols as a ...
Sanghyuk Jeon   +27 more
wiley   +1 more source

The choice of Hercules: pleasure, duty and the good life in the 21st century

open access: yes, 2008
Duty or Pleasure? This was the legendary choice which faced Hercules and which pre-eminent philosopher AC Grayling uses as the starting point of this masterful book.
Grayling, Anthony C.
core  

Herbicide Metabolic Resistance in Poaceae Plants via the GA‐GID1/DELLA‐DOF2‐P450s Module

open access: yesAdvanced Science, EarlyView.
Plant hormone signaling modulates herbicide resistance in Echinochloa crus‐galli. The GA–DELLA–DOF2 cascade directly activates P450 detoxification genes in two Poaceae species, uncovering a core mechanism of metabolic herbicide resistance. ABSTRACT Barnyard grass (Echinochloa crus‐galli) is one of the world's most important weeds, and the evolution of ...
Junzhi Wang   +6 more
wiley   +1 more source

Cassel Hercules v. Norden.

open access: yes
CASSEL HERCULES V. NORDEN. Cassel Hercules v. Norden. ( -

core   +1 more source

Disentangling the Hercules stream

open access: yes, 2007
Using high-resolution spectra of nearby F and G dwarf stars, we have investigated the detailed abundance and age structure of the Hercules stream.
Feltzing, S.   +7 more
core   +1 more source

Targeting the KCNC3‐Dependent Anterior Insular‐Lateral Orbitofrontal Cortex Glutamatergic Circuit Attenuates Post‐Traumatic Anxiety

open access: yesAdvanced Science, EarlyView.
Frontal lobe traumatic brain injury is associated with hyperactivity of an insular–orbitofrontal circuit in both patients and mice. By combination of integrating functional imaging, cell‐type–specific circuit manipulation, single‐cell transcriptomics, and whole‐cell recordings, this work identifies the downregulation of the potassium channel KCNC3 in ...
Meng‐Ge Li   +10 more
wiley   +1 more source

Signatures of Tidal Disruption of the Hercules Ultrafaint Dwarf Galaxy

open access: yesThe Astrophysical Journal
The Hercules ultrafaint dwarf galaxy (UFD) has long been hypothesized to be tidally disrupting, yet no conclusive evidence has been found for tidal disruption owing partly to difficulties in identifying Hercules member stars.
Xiaowei Ou   +8 more
doaj   +1 more source

Missile Industry-Hercules P.6

open access: yes, 1960
Hercules Plant, 1960.

core  

Home - About - Disclaimer - Privacy