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Hereditary Cancer in Clinical Practice, 2020 Background Matrix metalloproteinases (MMPs) and metallothioneins (MTs) are Zinc-related proteins which are involved in processes crucial for carcinogenesis such as angiogenesis, proliferation and apoptosis.
Katarzyna Białkowska +17 more
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Genetic testing for hereditary breast cancer in Poland: 1998–2022
Hereditary Cancer in Clinical Practice, 2023 BRCA1 and BRCA2 mutations contribute to both breast cancer and ovarian cancer worldwide. In Poland approximately 4% of patients with breast cancers and 10% of patients with ovarian cancer carry a mutation in BRCA1.
Jacek Gronwald +7 more
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Scientific Data, 2023 While the amount of studies involving single-cell or single-nucleus RNA-sequencing technologies grows exponentially within the biomedical research area, the kidney field requires reference transcriptomic signatures to allocate each cluster its matching ...
Marceau Quatredeniers +5 more
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Hong Kong–Macau Severe Hives and Angioedema Referral Pathway
Frontiers in Allergy, 2023 BackgroundUrticaria (defined as the presence of hives, angioedema, or both) can be caused by a variety of etiologies ranging from more common conditions such as chronic spontaneous urticaria (CSU) to rarer conditions such as hereditary angioedema (HAE ...
Philip H. Li +10 more
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Glucocorticoids Influencing Wnt/β-Catenin Pathway; Multiple Sites, Heterogeneous Effects
Molecules, 2020 Glucocorticoid hormones are vital; their accurate operation is a necessity at all ages and in all life situations. Glucocorticoids regulate diverse physiological processes and they use many signaling pathways to fulfill their effect.
Katalin Meszaros, Attila Patocs
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Translation and validation into Brazilian Portuguese of the Spastic Paraplegia Rating Scale (SPRS) [PDF]
Arquivos de Neuro-Psiquiatria, 2016 Hereditary spastic paraplegias (HSP) are characterized by progressive lower limb weakness and spasticity. There are no validated instruments to quantify disease severity in Portuguese.
Katiane R. Servelhere +3 more
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Hereditary topological diagonalizations and the Menger-Hurewicz Conjectures [PDF]
, 2010 We consider the question, which of the major classes defined by topological diagonalizations of open or Borel covers is hereditary. Many of the classes in the open case are not hereditary already in ZFC, and none of them is provably hereditary.
Bartoszynski, Tomek, Tsaban, Boaz
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Frontiers in Neurology, 2017 BackgroundSpinocerebellar ataxia type 2 (SCA2) is an inherited and still incurable neurodegenerative disorder. Evidence suggests that pro-oxidant agents as well as factors involved in antioxidant cellular defenses are part of SCA2 physiopathology.AimTo ...
Dennis Almaguer-Gotay +8 more
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Journal of Family Medicine and Primary Care, 2021 Bleeding tendency is a common medical problem that is usually caused by either coagulation factors abnormalities, platelets disorders, or vasculopathy. Detection of patients with high bleeding risk through history taking and accurate diagnosis followed ...
Mohammed A Zolaly +4 more
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Metastatic follicular thyroid cancer in a patient with Birt‐Hogg‐Dubé syndrome
Clinical Case Reports, 2021 Birt‐Hogg‐Dubé syndrome (BHDS) is an extremely rare genetic condition that predisposes to renal cell carcinoma. This case describes a novel case of a patient with BHDS who also develops follicular thyroid cancer.
Elisa K. Bongetti +3 more
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