Results 191 to 200 of about 791,916 (337)

Determining biomarkers for evaluation and diagnosis of hereditary angioedema

, 2022
Umesh Singh, Jonathan A. Bernstein
openalex   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Hereditary Spastic Paraparesis with Thin Corpus Callosum: Characteristic MRI Findings [PDF]

Türk Nöroloji Dergisi, 2011
Eser S Sanverdi, Kader K Oguz
doaj   +1 more source

Impact of Hereditary Cancer Susceptibility in Solid-Organ Transplant Recipients. [PDF]

JCO Precis Oncol
Khuu N, Jeanjean M, Donenberg T, Silva Smith R, Sussman D, Vianna R, Ciancio G, Guo Y, Tekin M, Borja NA.   +9 more
europepmc   +1 more source

Two novel germline mutations of MLH1 and investigation of their pathobiology in hereditary non-polyposis colorectal cancer families in China

, 2007
Chao‐Fu Wang, Xiao-Yan Zhou, Tai-Ming Zhang, Ye Xu, San-Jun Cai, Da-Ren Shi   +5 more
openalex   +2 more sources

Hereditary Hemolytic Anemia [PDF]

, 2020
National Cancer Institute
openalex   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Hereditary subependymal heterotopia associated with mega cisterna magna: antenatal diagnosis with magnetic resonance imaging [PDF]

, 2002
Núria Bargalló, B. Puerto, Carmen de Juan, Josep Maria Martínez-Crespo, Miren Olondo   +4 more
openalex   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

Skin cancer risk in hereditary mixed cancer syndromes. [PDF]

Hered Cancer Clin Pract
Nikkola V, Alakoski A, Mecklin JP, Seppälä TT, Nikkola J, Schrader K.   +5 more
europepmc   +1 more source