Results 31 to 40 of about 791,916 (337)

Distress, anxiety, and depression in persons with hereditary cancer syndromes: Results from a nationwide cross‐sectional study in Germany

Cancer Medicine, 2023
Background Persons with hereditary cancer syndromes (carriers) have a higher risk of developing cancer early. They are confronted with decisions regarding prophylactic surgeries, communication within their families, and childbearing.
Anna Maria Kastner, Josefine Fischer‐Jacobs, Jan Brederecke, Andrea Hahne, Tanja Zimmermann   +4 more
doaj   +1 more source

Phenotypic characterization of idiopathic epilepsy and epilepsy of unknown cause in Irish Setters

Frontiers in Veterinary Science, 2022
Canine epileptic seizures are common neurological symptom presenting to veterinary practice. Idiopathic epilepsy (IE) with a suspected genetic background has been reported in several dog breeds. Although it has been reported in the Irish Setter (IS), the
Marta Plonek, Montse M. Diaz-Espineira, Quirine E. M. Stassen, Koen M. Santifort, Peter A. J. Leegwater, Paul J. J. Mandigers, Paul J. J. Mandigers   +6 more
doaj   +1 more source

Approximating Hereditary Discrepancy via Small Width Ellipsoids

, 2014
The Discrepancy of a hypergraph is the minimum attainable value, over two-colorings of its vertices, of the maximum absolute imbalance of any hyperedge.
Nikolov, Aleksandar, Talwar, Kunal
core   +1 more source

Surgical and Systemic Treatment of Hereditary Breast Cancer: A Mini-Review With a Focus on BRCA1 and BRCA2 Mutations

Frontiers in Oncology, 2020
Hereditary breast cancer accounts for 5%–10% of breast cancer cases. The majority of familial cases have been linked to germline mutations in BRCA1 and BRCA2 genes, though other high penetrance susceptibility genes have also been identified through ...
Athanasios Pouptsis, Leyla Swafe, Maneesha Patwardhan, Chara Stavraka   +3 more
doaj   +1 more source

Linear rank-width of distance-hereditary graphs II. Vertex-minor obstructions

, 2017
In the companion paper [Linear rank-width of distance-hereditary graphs I. A polynomial-time algorithm, Algorithmica 78(1):342--377, 2017], we presented a characterization of the linear rank-width of distance-hereditary graphs, from which we derived an ...
Kanté, Mamadou Moustapha, Kwon, O-joung
core   +3 more sources

TP53 germline testing and hereditary cancer: how somatic events and clinical criteria affect variant detection rate

Genome Medicine
Background Germline heterozygous pathogenic variants (PVs) in TP53 cause Li-Fraumeni syndrome (LFS), a condition associated with increased risk of multiple tumor types. As the associated cancer risks were refined over time, clinical criteria also evolved
Paula Rofes, Carmen Castillo-Manzano, Mireia Menéndez, Álex Teulé, Sílvia Iglesias, Elisabet Munté, Mireia Ramos-Muntada, Carolina Gómez, Eva Tornero, Esther Darder, Eva Montes, Laura Valle, Gabriel Capellá, Marta Pineda, Joan Brunet, Lidia Feliubadaló, Jesús del Valle, Conxi Lázaro   +17 more
doaj   +1 more source

Hereditary Polytopes [PDF]

, 2012
Every regular polytope has the remarkable property that it inherits all symmetries of each of its facets. This property distinguishes a natural class of polytopes which are called hereditary.
Mixer, Mark, Schulte, Egon, Weiss, Asia Ivic   +2 more
core  

Hereditary hemochromatosis

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 2006
▪ Abstract  In recent years, the number of proteins implicated in iron homeostasis has increased dramatically, and genetic causes have apparently been identified for the major disorders associated with tissue iron overload. These dramatic steps forward have transformed the way we look at iron-related disorders, particularly hemochromatosis.
openaire   +4 more sources

A Quality Improvement Initiative to Standardize Pneumocystis jirovecii Pneumonia Prophylaxis in Pediatric Patients With Solid Tumors

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Pediatric patients with extracranial solid tumors (ST) receiving chemotherapy are at an increased risk for Pneumocystis jirovecii pneumonia (PJP). However, evidence guiding prophylaxis practices in this population is limited. A PJP‐related fatality at our institution highlighted inconsistent prescribing approaches and concerns about
Kriti Kumar, Denise M. Connolly, Ellen Kellington, Elyse Zelunka, Karla Kerrigan, Furqan Shaikh, Paul C. Nathan, Meredith S. Irwin, Sarah Cohen‐Gogo   +8 more
wiley   +1 more source

Hereditary properties of combinatorial structures: posets and oriented graphs

, 2007
A hereditary property of combinatorial structures is a collection of structures (e.g. graphs, posets) which is closed under isomorphism, closed under taking induced substructures (e.g. induced subgraphs), and contains arbitrarily large structures.
Balogh, József, Bollobás, Béla, Morris, Robert   +2 more
core   +2 more sources