Results 21 to 30 of about 14,685,767 (350)

Identification of a Comprehensive Spectrum of Genetic Factors for Hereditary Breast Cancer in a Chinese Population by Next-Generation Sequencing

PLoS ONE, 2015
The genetic etiology of hereditary breast cancer has not been fully elucidated. Although germline mutations of high-penetrance genes such as BRCA1/2 are implicated in development of hereditary breast cancers, at least half of all breast cancer families ...
Xiaochen Yang, Jiong Wu, Jin‐song Lu, Guangyu Liu, G. Di, Can-ming Chen, Yifeng Hou, Menghong Sun, Wentao Yang, Xiaojin Xu, Yingqi Zhao, Xin Hu, Da-Qiang Li, Z. Cao, Xiaoyan Zhou, Xiao-yan Huang, Zhe-bin Liu, Huan Chen, Yanzi Gu, Y. Chi, Xiangang Yan, Q. Han, Zhen‐zhou Shen, Z. Shao, Zhen Hu   +24 more
semanticscholar   +1 more source

Epidemiology of colorectal cancer: incidence, mortality, survival, and risk factors

Gastroenterology Review, 2019
According to GLOBOCAN 2018 data, colorectal cancer (CRC) is the third most deadly and fourth most commonly diagnosed cancer in the world. Nearly 2 million new cases and about 1 million deaths are expected in 2018.
Prashanth Rawla, T. Sunkara, Adam Barsouk   +2 more
semanticscholar   +1 more source

Guidelines for the management of hereditary colorectal cancer from the British Society of Gastroenterology (BSG)/Association of Coloproctology of Great Britain and Ireland (ACPGBI)/United Kingdom Cancer Genetics Group (UKCGG)

Gut, 2019
Heritable factors account for approximately 35% of colorectal cancer (CRC) risk, and almost 30% of the population in the UK have a family history of CRC.
K. Monahan, N. Bradshaw, Sunil Dolwani, B. Desouza, Malcolm G. Dunlop, J. East, Mohammad Ilyas, Asha Kaur, F. Lalloo, A. Latchford, M D Rutter, I. Tomlinson, H. J. W. Thomas, J. Hill   +13 more
semanticscholar   +1 more source

Response of cord blood cells to environmental, hereditary and perinatal factors: A prospective birth cohort study [PDF]

, 2018
BackgroundMany studies investigating the impact of individual risk factors on cord blood immune cell counts may be biased given that cord blood composition is influenced by a multitude of factors.
Müller, Loretta, Olga Gorlanova (3520529), Olga Gorlanova, Latzin, Philipp, Frey, Urs, Urs Frey, Martin Röösli (20795), Clemens Dahinden, Diana Reppucci (442447), Lurà, Marco Patrick, Proietti, Elena, Clemens Dahinden (5488925), Rodoljub Pavlovic (5488928), Martin Röösli, Philipp Latzin (46181), Reppucci, Diana, Pavlovic, Rodoljub, Loretta Müller (575079), Gorlanova, Olga, Loretta Müller, Elena Proietti (3497075), Philipp Latzin, Vienneau, Danielle, Diana Reppucci, Danielle Vienneau (459312), Marco Patrick Lurà, Röösli, Martin, Danielle Vienneau, Urs Frey (346875), Dahinden, Clemens, Marco Patrick Lurà (5488922), Elena Proietti, Rodoljub Pavlovic   +32 more
core   +1 more source

Genetic studies of hereditary thrombocythemia [PDF]

, 2013
Hereditary thrombocythemia (HT) is a familial myeloproliferative disorder characterized by an elevated platelet count in peripheral blood. Thrombocytosis is due to a genetic alteration that can be transmitted to the offspring.
Pianta, Annalisa
core   +1 more source

Hereditary breast cancer: syndromes, tumour pathology and molecular testing

Histopathology, 2022
Hereditary factors account for a significant proportion of breast cancer risk. Approximately 20% of hereditary breast cancers are attributable to pathogenic variants in the highly penetrant BRCA1 and BRCA2 genes.
A. Sokolova, K. Johnstone, A. M. McCart Reed, P. Simpson, S. Lakhani   +4 more
semanticscholar   +1 more source

WAO guideline for the management of hereditary angioedema

, 2012
Hereditary Angioedema (HAE) is a rare disease and for this reason proper diagnosis and appropriate therapy are often unknown or not available for physicians and other health care providers.
Ruby Pawankar, Richard Lockey, Magerl, Markus, Bowen, Tom, Lumry, William, Pawankar, Ruby, Craig, Timothy P., Craig, Timothy, Emel Aygören Pürsün, Anete Grumach, Bork, Konrad, Ritchie, Bruce, Katelaris, Constance H. (R12307), Bruce Zuraw, Alexander Nast, Farkas, Henrietta, Farkas, Henriette, Longhurst, Hilary, Martinez-Saguer, Immaculada, Nast, Alexander, Marcus Maurer, Henriette Farkas, Markus Magerl, Lockey, Richard, William Lumry, Tom Bowen, Zuraw, Bruce, Boysen, Henrik B., Martinez Saguer, Inmaculada, Konrad Bork, Grumach, Anete, Katelaris, Constance H., Hilary Longhurst, Aygören-Pürsün, Emel, Maurer, Marcus, Immaculada Martinez-Saguer, Bruce Ritchie, Henrik Boysen, Constance H. Katelaris, Timothy Craig   +39 more
core   +1 more source

Carcinomas and Carcinoid Tumors of the Lungs and Bronchi in Children and Adolescents: The EXPeRT Recommendations

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Primary lung carcinomas and bronchial carcinoid tumors (BC) are very rare malignancies in childhood. While typical BC and mucoepidermoid carcinomas are mostly low‐grade, localized tumors with a more favorable prognosis than in adults, necessitating avoidance of overtreatment, adenocarcinomas of the lung are often diagnosed at advanced disease ...
Michael Abele, Calogero Virgone, Michaela Kuhlen, Sabine Irtan, Yves Reguerre, Malgorzata Krawczyk, Ewa Bien, Tal Ben‐Ami, Maja Cesen, Ricardo Lopez‐Almaraz, Andrea Ferrari, Gianni Bisogno, Dominik T. Schneider, Abbas Agaimy, Constantin Lapa, Hubert Ducou le Pointe, Rainer Claus, Catherine Daniel, Ines B. Brecht, Daniel Orbach   +19 more
wiley   +1 more source

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen, Calogero Virgone, Antje Redlich, Michael Abele, Ricardo Lopez‐Almaraz, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Maja Mazic Cesen, Andrea Ferrari, Malgorzata A. Krawczyk, Yves Reguerre, Dominik T. Schneider, Ines B. Brecht, Charlotte Rigaud, Bilgehan Yalcin, Rainer Claus, Christian Vokuhl, Constantin Lapa, Jörg Fuchs, Segolene Hescot, Thomas Walter, Julien Hadoux, Daniel Orbach   +23 more
wiley   +1 more source

Hereditary factors of bruxism

Journal of Craniomaxillofacial Research, 2020
Background: Bruxism is a parafunctional disorder. The prevalence of this rhythmic activity of rodent muscles is reported to be about %8. This disease can compromise the life quality of a person’s general performance. The aim of this study is to gather information upon genetic factors, which contribute to the pathogenesis of the disease.
Shamsoulmolouk Najafi, Zahra Faraji, Hassan Roudgari   +2 more
openaire   +2 more sources