Results 141 to 150 of about 192,458 (292)
Liver Involvement in Celiac Disease and Immune‐Mediated Diseases of the Small Bowel
Liver International, Volume 45, Issue 8, August 2025.ABSTRACT Disorders of the hepatobiliary system are commonly associated with gastrointestinal (GI) diseases. The GI and hepatobiliary systems interact through the portal vein system and enterohepatic circulation, creating a gut–liver axis that allows for a complex multidirectional interplay between immune, hormonal, dietary and environmental luminal ...
Nicoletta Nandi +8 more
wiley +1 more source
Italian Journal of Medicine, 2012 IntroductionHereditary hemochromatosis (HH) is an autosomal recessive disorder caused by mutations in the HFE gene, which increase intestinal iron absorption.
Paolo Agostinis +8 more
doaj +1 more source
THE PATHOGENESIS OF HEREDITARY HEMOCHROMATOSIS
The FASEB Journal, 2009 Hereditary hemochromatosis (HH) is an iron overload disease which can result from mutations in HFE, transferrin receptor 2 (TfR2), hemojuvelin (HJV) or hepcidin, all of which lead to inadequate synthesis of the iron‐regulatory hormone hepcidin. Hepcidin deficiency in HH results in excessive iron absorption. In normal homeostasis, hepcidin production is
Emilio Ramos +2 more
openaire +2 more sources
The FASEB Journal, Volume 39, Issue 14, 31 July 2025.Ferroportin 1 is an iron exporter belonging to the Major Facilitator Superfamily. Its unusual intracellular gate is formed by asymmetric networks of non‐covalent bonds. We analyzed these networks using Molecular Dynamics simulations and experimental tests and identified novel amino acids as key players in inter‐lobe connections.
Marlène Le Tertre +8 more
wiley +1 more source
Hemochromatosis and Heart Involvement
Архивъ внутренней медициныHemochromatosis is a life-threatening condition if left untreated, that is caused by excess iron in the body. It can be primary (hereditary) hemochromatosis, resulting from genes mutations, and secondary (acquired) as a result of excessive intake of iron
E. V. Reznik +3 more
doaj +1 more source
Case Reports in Gastroenterology, 2016 Introduction: Hereditary hemochromatosis features a dysregulated iron absorption leading to iron overload and organ damage. The regulation of total hemoglobin mass during depletion of iron deposits by therapeutic phlebotomy has not been studied.
Nina Wrobel +4 more
doaj +1 more source
Evaluation of a Nucleic Acid-based Cross-Linking Assay to Screen for Hereditary Hemochromatosis in Healthy Blood Donors [PDF]
, 2000 Christiane Wylenzek +5 more
openalex +1 more source
Genetic Information and the Workplace - Full Report [PDF]
, 1998 Joint Agency ReportGeneticInfoWorkplace1998.pdf: 800 downloads, before Oct.
Department of Health and Human Services, U.S. +2 more
core +1 more source
مجلة علوم ذي قارHemochromatosis is a prevalent hereditary disorder that causes excess iron to build up in the body to dangerous levels. Hereditary hemochromatosis, also known as HFE-related hemochromatosis is carried on by changes in the HFE gene.
Thanaa Kalil Ibrahim +3 more
doaj +1 more source
Improved Molecular Diagnosis of Hereditary Hemochromatosis Using a DNA Enzyme Immunoassay [PDF]
, 2000 Mara Biasin +5 more
openalex +1 more source