Results 41 to 50 of about 21,378 (292)
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Arteriovenous Malformations in Hereditary Haemorrhagic Telangiectasia
Acta Médica Portuguesa, 2014 Keywords: Arteriovenous Malformations; Telangiectasia, Hereditary Hemorrhagic; Tomography, X-Ray Computed.
Klaus Loureiro Irion +1 more
doaj +1 more source
The Brain in Hereditary Hemorrhagic Telangiectasia [PDF]
Stroke, 1971 While neurological symptoms are often mentioned in reports of families with hereditary hemorrhagic telangiectasia (HHT) and are frequently assumed to be due to vascular anomalies of the central nervous system, documentation of such anomalies is surprisingly rare.
T J, Reagan, W H, Bloom
openaire +2 more sources
Impact of Asymptomatic Intracranial Hemorrhage on Outcome After Endovascular Stroke Treatment
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Endovascular treatment (EVT) achieves high rates of recanalization in acute large‐vessel occlusion (LVO) stroke, but functional recovery remains heterogeneous. While symptomatic intracranial hemorrhage (sICH) has been well studied, the prognostic impact of asymptomatic intracranial hemorrhage (aICH) after EVT is less certain ...
Shihai Yang +22 more
wiley +1 more source
Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina +11 more
wiley +1 more source
Osler-Weber-Rendu Disease Uncovered by Preeclampsia in a Case Report
Case Reports in Obstetrics and Gynecology, 2020 Osler-Weber-Rendu disease (OWRD), called hereditary hemorrhagic telangiectasia, is an uncommon genetic illness with the dominant autosomal transmission.
Jamal Ouachaou +7 more
doaj +1 more source
HEREDITARY HEMORRHAGIC TELANGIECTASIA
, 2020 Hereditary hemorrhagic telangiectasia is an autosomal dominant vascular disorder. It is characterized by mucocutaneous telangiectases, recurrent epistaxis, gastrointestinal bleeding, and arteriovenous malformations (AVMs) in the lungs, brain, and liver ...
Kjeldsen, Anette Drøhse; id_orcid +3 more
core +1 more source
, 2022 Hereditary hemorrhagic telangiectasia is regarded as a high hemorrhagic risk condition, and the management of anticoagulation and heart surgery in these patients can be challenging.
Nestola, P. L. +7 more
core +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective High‐resolution MRI enables detailed assessment of intracranial vessel wall pathology in moyamoya vasculopathy. We aimed to classify adult moyamoya vasculopathy etiologies using high‐resolution MRI and to examine subtype‐specific associations between high‐resolution MRI features and ischemic infarction.
Guangsong Han +8 more
wiley +1 more source
The Pan African Medical Journal, 2016 Hereditary hemorrhagic telangiectasia is a rare autosomal dominant inherited disease that is usually complicated by visceral vascular malformations. Patients harboring such malformations are at increased risk of brain abscess formation, which despite ...
Marios Themistocleous +5 more
doaj +1 more source