Hereditary Multiple Exostoses-A Review of the Molecular Background, Diagnostics, and Potential Therapeutic Strategies. [PDF]
Front Genet, 2021 Hereditary multiple exostoses (HMEs) syndrome, also known as multiple osteochondromas, represents a rare and severe human skeletal disorder. The disease is characterized by multiple benign cartilage-capped bony outgrowths, termed exostoses or ...
Bukowska-Olech E +8 more
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Spontaneous Regression of Multiple Osteochondromas in a Patient With Hereditary Multiple Exostoses: A Case Report. [PDF]
CureusHereditary multiple exostoses (HME) is an autosomal dominant disorder characterized by the development of multiple osteochondromas, primarily near the metaphyses of long bones.
Ikeda K, Teruya S, Tsuge H, Onishi S.
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Ulnar lengthening in the treatment of forearm deformity caused by hereditary multiple exostoses in children. [PDF]
World J OrthopHereditary multiple exostoses (HME) is an autosomal dominant bone disorder characterized by abnormal bone development. HME mostly involves the forearm, resulting in forearm deformities, limited functional activities, etc.
Wang S +7 more
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A Rare Case of Hereditary Multiple Exostoses in a Woman. [PDF]
Orthop NursHereditary multiple exostosis (HME) is a rare genetic disorder characterized by multiple bony spurs or lumps, commonly affecting the long bones. This case report exposes the clinical presentation, diagnosis, and management of HME in a 28-year-old female ...
Ghamri RA.
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Intrathecal Fentanyl Pump Placement in a Patient With Chronic Pain Caused by Hereditary Multiple Exostoses: A Case Report. [PDF]
CureusHereditary multiple exostoses (HME) is a genetic disorder defined by the formation of benign bone tumors known as exostoses, which can lead to chronic pain and functional impairment. This case report details a 57-year-old man with a long-standing history
Tageant H +5 more
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Haploinsufficiency of EXT1 and Heparan Sulphate Deficiency Associated with Hereditary Multiple Exostoses in a Pakistani Family. [PDF]
Medicina (Kaunas), 2022 Background and Objectives: Hereditary multiple exostoses (HME) is a disease characterized by cartilage-capped bony protuberances at the site of growth plates of long bones.
Ajmal M +5 more
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An Unusual Presentation of Costal Intraspinal Osteochondroma Causing Compressive Myelopathy in a Patient With Hereditary Multiple Exostoses: A Case Report and Literature Review. [PDF]
CureusA 22-year-old man presented to us with back pain for four months, inability to walk, and weakness in both lower limbs. Clinical examination revealed multiple swellings in the body, motor weakness, paresthesia, and upper motor neuron signs.
Jeevo J, N V A, Shekoba M.
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Ulnar lengthening for children with forearm deformity from hereditary multiple exostoses: a retrospective study from a tertiary medical center. [PDF]
BMC PediatrPatients with hereditary multiple exostosis (HME) usually present with forearm deformity with or without radial head dislocation. Ulna lengthening has been proposed to address this condition.
Wang S +6 more
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Osteochondroma formation is independent of heparanase expression as revealed in a mouse model of hereditary multiple exostoses. [PDF]
J Orthop Res, 2022 Hereditary multiple exostoses (HME) is a rare, pediatric disorder characterized by osteochondromas that form along growth plates and provoke significant musculoskeletal problems.
Mundy C +5 more
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Clinical survey of a pedigree with hereditary multiple exostoses and identification of EXT‑2 gene deletion mutation. [PDF]
Mol Med Rep, 2022 The aim of the present study was to report a clinical survey of hereditary multiple exostoses (HME) in a large Chinese pedigree, and the identification of a novel deletion mutation of exostosin glycosyltransferase 2 (EXT-2) gene.
Wang W +8 more
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