Results 121 to 130 of about 1,132 (155)

Genetic screening of EXT1 and EXT2 in Cypriot families with hereditary multiple osteochondromas

Journal of Genetics, 2015
The purpose of this study was to perform genetic screening of the exostosin 1 (EXT1) and exostosin 2 (EXT2) genes in Cypriot patients with a clinical diagnosis of hereditary multiple osteochondromas (HMO). Initially, mutation analysis of the EXT1 gene was performed by Sanger sequencing.
Vassos Neocleous, G A Tanteles, Violetta Christophidou-Anastasiadou   +2 more
exaly   +3 more sources

Clinical and Radiographic Analysis of Osteochondromas and Growth Disturbance in Hereditary Multiple Exostoses

Journal of Pediatric Orthopaedics, 2000
Hereditary multiple exostoses (HME) is traditionally described as a skeletal dysplasia. However, the discovery that the EXT family of tumour suppressor genes are responsible for HME suggests that it is more appropriate to classify HME as a familial neoplastic trait.
D E Porter, A H R W Simpson
exaly   +3 more sources

A New Classification System for Forearm Deformities Caused by Hereditary Multiple Osteochondromas

Journal of Hand Surgery
The objective of this study was to evaluate the Masada and Jo classifications for clinical use in patients with forearm deformity caused by hereditary multiple osteochondroma and propose a new classification system that is all-inclusive and can guide clinical management.A retrospective review of 275 forearms was performed.
Kai Yet Lam, Chloe Chan Xiaoyun, Bo Ning   +2 more
exaly   +3 more sources

A Unique Case of Hereditary Multiple Osteochondromas in the Feet

Forensic Anthropology, 2023
This report describes the differential diagnosis of osseous growths in the first metatarsals of an adult male previously unreported in the literature. Examination of the remains via macroscopic analysis and conventional radiography identified unusual bilateral growths arising from the lateral aspects of the first metatarsals with growth directed ...
Clara Devota, Kelly Kamnikar, Carolyn Isaac, Joseph Hefner   +3 more
openaire   +1 more source

Osteochondroma and Hereditary Multiple Osteochondromas

2021
Osteochondroma is the most common bone tumor, mainly affecting patients under 20 years of age. It presents in 90% of the cases as a solitary lesion. The remaining cases are part of the multiple hereditary osteochondromas syndrome. The pathogenesis is not entirely clear. Osteochondromas usually develop at the metaphysis of long bones.
openaire   +1 more source

Intra-articular acetabular osteochondroma in patients with multiple hereditary exostoses

Journal of Pediatric Orthopaedics B, 2021
We report three additional cases of intra-articular acetabular osteochondroma in multiple hereditary exostoses patients in order to raise the awareness of this rare location, to prompt early diagnosis, and to present various treatment options according to the patient’s condition.
Ashima, Choudhry, Geunwu, Gimm, Ho Won, Kang, Chang Ho, Shin, Won Joon, Yoo, In-Ho, Choi, Tae-Joon, Cho   +6 more
openaire   +2 more sources

Incidental finding of hereditary multiple osteochondroma causing ischiofemoral impingement

BMJ Case Reports, 2021
Ischiofemoral impingement (IFI) has been described in the medical literature as a cause of hip pain. IFI occurs due to an abnormal contact or reduced space between the lesser trochanter and the lateral border of the ischium and is an often unrecognised cause of pain and snapping in the hip.
Ahmed Elnaggar, Roy Abraham, Shaher Hasanain, Khalid Al Hamadi   +3 more
openaire   +2 more sources

THE UNUSUAL PRESENTATION OF EXCESSIVE SPURS LIKE OSTEOCHONDROMAS IN AN ADOLESCENT WITH HEREDITARY MULTIPLE OSTEOCHONDROMAS

INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH, 2022
Hereditary Multiple Osteochondromatosis (HMO) is characterised by the presence of multiple osteochondromas, mainly affecting the long bones. Osteochondromas are bony projections that are either sessile or pendulated in form. Isolated osteochondromas in the form of spurs have been described as occurring in the knee and the foot.
Nikolaos Laliotis, Chrysanthos Chrysanthou, Panagiotis Konstandinidis   +2 more
openaire   +1 more source

Syringomyelia and vertebral osteochondromas in patients with multiple hereditary exostosis

Journal of Pediatric Orthopaedics B, 2014
Involvement of osteochondromas in the spinal canal occurs in patients with multiple hereditary exostosis, but the exact prevalence is unknown. A recent study found an incidence of 68%, with 27% of these lesions encroaching into the spinal canal.
Robert L, Thompson, Pooya, Hosseinzadeh, Ryan D, Muchow, Vishwas R, Talwalkar, Henry J, Iwinski, Janet L, Walker, Todd A, Milbrandt   +6 more
openaire   +2 more sources

Management of deformities of the forearm in multiple hereditary osteochondromas.

The Journal of Bone & Joint Surgery, 1984
A patient with multiple hereditary osteochondromas may have any of several severe deformities of the forearm, the most common of which are ulnar deviation of the wrist associated with relative shortening of the ulna, bowing of either or both of the bones of the forearm, shortening of the forearm, and late dislocation of the radial head.
G R, Fogel, E C, McElfresh, H A, Peterson, P T, Wicklund   +3 more
openaire   +2 more sources