Results 161 to 170 of about 1,261 (184)

Gene Variants Characterize and Distinguish Osteochondromas in Patients With Hereditary Multiple Osteochondromas

Journal of Orthopaedic Research
ABSTRACT Hereditary Multiple Osteochondromas (HMO) is a rare, pediatric skeletal disorder characterized by osteochondromas that form along the growth plates. These benign tumors can cause skeletal deformities, joint dysfunction, chronic pain and other health problems. Most HMO patients are born with a heterozygous
Christina Mundy, Sadhana Ramesh, Caroline Kim, Divya Talwar, Maurizio Pacifici, Alexandre Arkader   +5 more
openaire   +2 more sources

Multiple Hereditary Exostoses with Tetraparesis Due To Cervical Spine Osteochondroma

World Neurosurgery, 2018
This is a case report of a 34-year-old man with hereditary multiple exostoses who presented with gradual tetraparesis. Neuroimaging evaluation revealed an important posterior spinal cord compression by a C3 bony formation. Following posterior microsurgical decompression, the patient recovered nearly completely.
Ali, Akhaddar, Mohamed, Zyani, Issam, Rharrassi   +2 more
openaire   +2 more sources

Hereditary Multiple Osteochondromas

Consultant, 2021
Zackary Funk, Priya Sharma, Carolyn Carter   +2 more
openaire   +1 more source

Rate of Spinal Osteochondromas Diagnosed in Pediatric Patients With Hereditary Multiple Osteochondromas

Journal of Pediatric Orthopaedics
Background: Hereditary multiple osteochondromas (HMO) is a common pediatric condition defined by multiple cartilage-capped bony lesions. Spinal osteochondromas affect up to 68% of HMO patients. Although most are asymptomatic, intraspinal osteochondromas can cause significant neurological symptoms and morbidity.
Jack Legler, Lee. R. Benaroch, Ali Ahmadi Pirshahid, Olivia Serhan, Draydon Cheng, Debra Bartley, Timothy Carey, Parham Rasoulinejad, Supriya Singh, Patrick Thornley   +9 more
openaire   +2 more sources

EXT2-positive multiple hereditary osteochondromas with some features suggestive of metachondromatosis

Skeletal Radiology, 2011
Metachondromatosis (MC) and hereditary multiple osteochondromas (HMO) are thought to be distinct disorders, each with characteristic x-ray and clinical features. Radiographic differences are the current mainstay of differential diagnosis. Both disorders are autosomal dominant, but the majority of patients with HMO have mutations in EXT-1 or EXT 2 genes.
Neil C, Vining, Stephen, Done, Ian A, Glass, Shawn E, Parnell, Darci L, Sternen, Kathleen A, Leppig, Vincent S, Mosca, Michael J, Goldberg   +7 more
openaire   +2 more sources

Clinical and Radiographic Analysis of Osteochondromas and Growth Disturbance in Hereditary Multiple Exostoses

Journal of Pediatric Orthopaedics, 2000
Hereditary multiple exostoses (HME) is traditionally described as a skeletal dysplasia. However, the discovery that the EXT family of tumour suppressor genes are responsible for HME suggests that it is more appropriate to classify HME as a familial neoplastic trait.
D E, Porter, M E, Emerton, F, Villanueva-Lopez, A H, Simpson   +3 more
openaire   +2 more sources

Intracanalicular Osteochondroma Producing Spinal Cord Compression in Hereditary Multiple Exostoses

Journal of Spinal Disorders, 1994
Spinal cord compression is an unusual but potentially catastrophic manifestation of hereditary multiple exostoses (HMEs). Isolated, osteochondromas are usually of little significance. However, if they are located near neurologic structures, they may cause irritation due to mechanical compression. In patients with HMEs who present with neck or back pain,
M F, O'Brien, K H, Bridwell, L G, Lenke, P L, Schoenecker   +3 more
openaire   +2 more sources

Giant osteochondroma of axis in a child with multiple hereditary exostoses

Journal of Pediatric Orthopaedics B, 2012
Though osteochondromas are the most common benign bone tumour, their spinal involvement is less frequent. We report a case of osteochondroma in a 5-year-old female child with multiple hereditary exostoses that originated from posterior elements of C2 vertebra, not involving spinal canal and caused restriction of neck movement.
Naveen, Tahasildar, Pebam, Sudesh, Vijay, Goni, Sujit Kumar, Tripathy   +3 more
openaire   +2 more sources

Osteochondroma and Multiple Hereditary Exostosis

2022
Krishna V. Suresh, Paul D. Sponseller
openaire   +1 more source

Osteochondroma with Cervical Cord Compression in Hereditary Multiple Exostoses

Spine, 1990
S A, Shapiro, T, Javid, T, Putty
openaire   +2 more sources