Results 11 to 20 of about 1,261 (184)

Hereditary multiple exostoses with a giant osteochondroma degenerated into chondrosarcoma [PDF]

Radiology Case Reports
We present a case of hereditary multiple exostoses with malignant transformation to chondrosarcoma in a woman complaining of enlargement and pain in the right thigh.
Federica Masino, MD, Manuela Montatore, MD, Rossella Carpentiere, MD, Marina Balbino, MD, Rossella Gifuni, MD, Giacomo Fascia, MD, Giuseppe Guglielmi, MD   +6 more
doaj   +5 more sources

An Abnormal Presentation of a Popliteal Artery Mass and a Unique Cause of Claudication [PDF]

Case Reports in Orthopedics
Multiple hereditary exostosis (MHE) is a rare autosomal-dominant disorder marked by multiple osteochondromas arising from the metaphyses of long bones.
Jamil Haddad, Majed Alzahabi, Saif L. Juma, Nicholas David Cominos, Shariff K. Bishai   +4 more
doaj   +3 more sources

Current paediatric orthopaedic practice in hereditary multiple osteochondromas of the forearm: a systematic review [PDF]

SICOT-J, 2018
Introduction: This systematic review aims to answer three research questions concerning the management of hereditary multiple osteochondromas of forearm in children: What is the best available evidence for the currently employed surgical procedures? What
EL-Sobky Tamer A., Samir Shady, Atiyya Ahmed Naeem, Mahmoud Shady, Aly Ahmad S., Soliman Ramy   +5 more
doaj   +4 more sources

Two Siblings Followed Up for Hereditary Multiple Exostoses [PDF]

Haseki Tıp Bülteni, 2014
Hereditary multiple exostoses is an autosomal dominant disease with abnormal bone formation especially at the long bones. Osteochondromas, which occur in the course of the disease, can cause growth disturbances in affected children.
Meltem Erol, Özgül Yiğit, Oktay Adanır, Mehmet Toksöz, Halis Narin, Veysel Gök, Dilek Borakay, Murat Konya   +7 more
doaj   +2 more sources

Bone deformities with hereditary multiple osteochondromas [PDF]

Danish Medical Journal
INTRODUCTION. Hereditary multiple osteochondromas (HMO) is a genetic skeletal disorder caused by defects in exostosin glycosyltransferase 1 (EXT1) or 2 (EXT2) genes. It develops mainly in the growth period and causes multiple osteochondromas (OC) in the physis of the long bones, leading to discomfort and deformities. This study aimed to investigate the
Brink Petersen, Rikke, Buch, Christina Damgaard, Færgemann, Christian, Nymark, Tine   +3 more
openaire   +5 more sources

Bilateral scapulothoracic osteochondromas in a patient with hereditary multiple exostosis: a case report and review of the literature [PDF]

Orthopedic Reviews, 2016
Hereditary multiple exostosis (HME) is an autosomal dominant disorder characterized by two or more benign growing, cartilage capped tumors of long bones called osteochondromas.
Markus Rupp, Jendrik Hardes, Michael J. Raschke, Adrian Skwara   +3 more
doaj   +3 more sources

A 40-Year-Old Male Presenting with Hereditary Multiple Exostosis: Management and Considerations [PDF]

Case Reports in Orthopedics, 2019
Hereditary multiple exostosis is a rare condition in which numerous benign osteochondromas form throughout the body, typically in areas of high bone turnover such as the metaphyseal plates of long bones.
Matthew Wells, Zackary Birchard
doaj   +2 more sources

Osteochondroma Arising from Dorsal Pedicle Causing Compressive Myelopathy [PDF]

Journal of Orthopaedic Case Reports
Introduction: Osteochondromas are benign bony neoplasms typically located in long bones, though they may occasionally occur in the posterior elements of the spine.
Mantu Jain, Nikhil Unnava, Rabi Narayan Sahu, Kanav Gupta, Raghavendra Balagod, Abhijith K Jayan   +5 more
doaj   +2 more sources

Malignancy Ratio in Pediatric Patients with Hereditary Multiple Exostoses: True Association or Reporting Bias? [PDF]

Pediatric Reports
Background: Hereditary Multiple Exostoses (HME) is a rare autosomal dominant skeletal disorder resulting from loss-of-function variants in the EXT1, EXT2, or EXT3 genes. While malignant transformation into chondrosarcoma is well documented, the incidence
Francesco Fabrizio Comisi, Andrea Maria Comisi, Elena Esposito, Salvatore Savasta   +3 more
doaj   +2 more sources

Prevalence of Osteochondromas in the Spine in Patients with Multiple Hereditary Exostoses

JBJS Open Access
Background:. Multiple hereditary exostoses (MHE) is an autosomal-dominant disorder characterized by the development of multiple cartilage-capped exostoses originating from the physis that are known as osteochondromas.
Carlos Monroig-Rivera, MD, Lauren Bockhorn, MD, David Thornberg, BS, Brenda Santillan, BS, Karl E. Rathjen, MD   +4 more
doaj   +3 more sources