Results 51 to 60 of about 1,639 (208)

Skeletal pathologies in extant crocodilians as a window into the paleopathology of fossil archosaurs

The Anatomical Record, EarlyView.
Abstract Crocodilians, together with birds, are the only extant relatives to many extinct archosaur groups, making them highly important for interpreting paleopathological conditions in a phylogenetic disease bracketing model. Despite this, comprehensive data on osteopathologies in crocodilians remain scarce.
Alexis Cornille, Kyla Beguesse, Ewan Wolff, Clemens Zinner, Patrick Asbach, François Clarac, Florian Witzmann   +6 more
wiley   +1 more source

Microhomology-mediated mechanisms underlie non-recurrent disease-causing microdeletions of the FOXL2 gene or its regulatory domain [PDF]

, 2013
Genomic disorders are often caused by recurrent copy number variations (CNVs), with nonallelic homologous recombination (NAHR) as the underlying mechanism.
BEYSEN, DIANE, Carvalho, Claudio MB, D'haene, Barbara, De Baere, Elfride, Lapunzina, Pablo, Lupski, James R, Menten, Björn, Nevado, Julian, Novikova, Yana, Sante, Tom, Verdin, Hannah   +10 more
core   +4 more sources

Popliteal artery pseudoaneurysm caused by non–penetrating trauma in a patient with hereditary multiple osteochondromatosis

Radiology Case Reports, 2022
Hereditary multiple osteochondromatosis is a genetic condition characterized by the appearance of numerous osteochondromas, which can cause pseudoaneurysms in rare cases.
Oscar Andrés Parada Duarte, MD, Juan Guillermo Arámbula Neira, MD, Valeria del Castillo Herazo, MD, María Fernanda Oviedo Lara, MD, Adriana Lucía López Polanco, MD, Andrés Felipe Durán Omaña, MD, Andrés Felipe Herrera Ortiz, MD   +6 more
doaj   +1 more source

Examining the Role of Artificial Intelligence in Assessment: A Comparative Study of ChatGPT and Educator‐Generated Multiple‐Choice Questions in a Dental Exam

European Journal of Dental Education, EarlyView.
ABSTRACT Aim To compare the item difficulty and discriminative index of multiple‐choice questions (MCQs) generated by ChatGPT with those created by dental educators, based on the performance of dental students in a real exam setting. Materials and Methods A total of 40 MCQs—20 generated by ChatGPT 4.0 and 20 by dental educators—were developed based on ...
Nezaket Ezgi Özer, Yusuf Balcı, Gaye Bölükbaşı, Betul İlhan, Pelin Güneri   +4 more
wiley   +1 more source

Rapidly acquired valgus deformity of the knee after osteochondroma resection in multiple hereditary exostoses pediatric patients: A report of two cases

Radiology Case Reports, 2022
Patients with multiple hereditary exostoses (MHE) often develop leg length discrepancies and limb alignment deformity around the knee as part of the natural course of the disease. Limb alignment deformity occurring post-resection of an osteochondroma has
Alexandra H. Aitchison, BS, David Alcoloumbre, MD, Ana C. Belzarena, MD, John S. Blanco, MD   +3 more
doaj   +1 more source

An Atypical Hip Pain in a Recreational Athlete: A Case Report

Clinical Case Reports, Volume 14, Issue 5, May 2026.
ABSTRACT Osteochondromas are the most common benign bone tumors, but pelvic involvement is rare. We present a case of an iliac osteochondroma manifesting with atypical hip pain, adding to the limited literature on pelvic osteochondromas and highlighting the diagnostic and management challenges of such cases in an athletic population. A 28‐year‐old male
Qvick Milan, Steyaert Adelheid, Watteyne Karel   +2 more
wiley   +1 more source

Bone deformities with hereditary multiple osteochondromas

Danish Medical Journal
INTRODUCTION. Hereditary multiple osteochondromas (HMO) is a genetic skeletal disorder caused by defects in exostosin glycosyltransferase 1 (EXT1) or 2 (EXT2) genes. It develops mainly in the growth period and causes multiple osteochondromas (OC) in the physis of the long bones, leading to discomfort and deformities. This study aimed to investigate the
Brink Petersen, Rikke, Buch, Christina Damgaard, Færgemann, Christian, Nymark, Tine   +3 more
openaire   +3 more sources

An unusual example of hereditary multiple exostoses: a case report and review of the literature

BMC Musculoskeletal Disorders, 2021
Background Hereditary multiple exostoses (HME) is a rare skeletal disorder characterised by a widespread. distribution of osteochondromas originating from the metaphyses of long bones. Case presentation This case study examines a 55-year-old male cadaver
Rebecca Chilvers, James A. Gallagher, Nathan Jeffery, Alistair P. Bond   +3 more
doaj   +1 more source

Costal exostosis at risk of hepatic injury in a 10-year-old girl

Journal of Pediatric Surgery Case Reports, 2022
Hereditary multiple exostosis (HME) is a rare skeletal genetic disorder with multiple and disseminated osteochondromas. Costal localization is found in 40% of cases.
M. Doan, B. Tschopp, A. Binet, J.-M. Joseph, A. Bregou Bourgeois   +4 more
doaj   +1 more source

Acral Mesenchymal Spindle Cell Neoplasm With a Novel HMGA2::NCOA2 Fusion

Journal of Cutaneous Pathology, Volume 53, Issue 5, Page 402-406, May 2026.
ABSTRACT Molecular profiling has revolutionized the field of soft tissue pathology, enhancing diagnostic precision and treatment strategies. The integration of molecular analysis and immunohistochemistry has been crucial for classifying diagnostically challenging acral mesenchymal neoplasms.
Grace Z. Armstrong, Carina A. Dehner, Eitan Halper‐Stromberg, Esther Baranov, Anna C. Eden, Rachel P. Kowal   +5 more
wiley   +1 more source