Results 81 to 90 of about 1,261 (184)

The Pathophysiological Functions of Heparanases: From Evolution, Structural and Tissue‐Specific Perspectives

open access: yesThe FASEB Journal, Volume 39, Issue 17, 15 September 2025.
Heparanase 1 (HPSE1) and Heparanase 2 (HPSE2) exhibit opposing expression patterns and functions in pathological contexts, such as cancer. Here, we describe their specific expression in immune cells and their implications in skin diseases. Although they are structurally similar and considered to be ‘cousins’, we found no common ancestor and that HPSE2 ...
Elham Vahdatahar   +12 more
wiley   +1 more source

Teleangiectatic Osteosarcoma Treated by Surgery and Chemotherapy: A Report of 223 Affected Patients From the Cooperative Osteosarcoma Study Group (COSS)

open access: yesCancer Medicine, Volume 14, Issue 17, September 2025.
ABSTRACT Purpose Teleangiectatic osteosarcoma is a histologic subtype of osteosarcoma that can mimic aneurysmal bone cysts and has so far been incompletely characterized. Patients and Methods We used the database of the Cooperative Osteosarcoma Study Group COSS (patient‐registration 1980–2019) to better understand this rare histologic variant.
Stefan S. Bielack   +17 more
wiley   +1 more source

Advances in the pathogenesis and possible treatments for multiple hereditary exostoses from the 2016 international MHE conference [PDF]

open access: yes, 2017
Multiple hereditary exostoses (MHE) is an autosomal dominant disorder that affects about 1 in 50,000 children worldwide. MHE, also known as hereditary multiple exostoses (HME) or multiple osteochondromas (MO), is characterized by cartilage-capped ...
Jeffrey D. Esko   +5 more
core   +1 more source

Hereditary Multiple Exostoses with Rare Ocular Finding: A Case Report

open access: yesJournal of Current Ophthalmology
Purpose: To study rare ocular findings in a rare case of hereditary multiple exostoses (HME) and to study HME in one family. Methods: HME is an autosomal dominant genetic disease characterized by the presence of multiple exostoses (osteochondromas).
Shashi Tanwar   +3 more
doaj   +1 more source

Multiple exostoses and an osteochondroma in a Pliocene canid from Langebaanweg ‘E’ Quarry (South Africa)

open access: yesJournal of Anatomy, Volume 247, Issue 3-4, Page 856-868, September/October 2025.
Overview of XS of pathological radius. Using anatomical descriptions, CT scanning and bone histology, we investigate several skeletal overgrowths of bone (exostoses) in the skeleton of a jackal‐like canid from the world famous Langebaanweg, a Mio‐Pliocene locality in South Africa.
Anusuya Chinsamy, Alberto Valenciano
wiley   +1 more source

Evaluation of forearm abnormalities; clinical and cosmetic results of surgical treatment in patients with multiple hereditaryextoses - multiple osteochondromas. [PDF]

open access: yes, 2013
Background: Forearm osteochondromas are found in a vast majority of patients diagnosed with Multiple Hereditary Exostoses - Multiple Osteochondromas (MHE-MO). Common complaints include pain, functional impairment, and cosmetic concerns. So far, there is
Flipsen, M.
core  

Modified resection technique for proximal fibular osteochondromas [PDF]

open access: yes, 2011
SummaryOsteochondroma is one of the most common tumors arising from the proximal fibula. Surgical treatment of proximal fibula osteochondromas may vary from debulking to resection of proximal fibula. We describe a modified surgical technique for excision
Bali, K.   +11 more
core   +1 more source

Multiple hereditary exostoses as a rare nonatherosclerotic etiology of chronic lower extremity ischemia [PDF]

open access: yes, 2010
Nonatherosclerotic etiologies of arterial insufficiency are uncommon but important causes of chronic lower extremity ischemia. We report a patient with multiple hereditary exostoses (MHE) presenting with lifestyle-limiting lower extremity claudication ...
Khan, Imtiaz   +5 more
core   +1 more source

Multiple hereditary osteochondroma presenting as spastic paraplegia

open access: yesInternational Journal of Contemporary Pediatrics
Osteochondromas are benign bony tumours with only 1–4% being located in the spine.  Compressive myelopathy as a presentation of vertebral osteochondroma in a child is a rare entity. Our case being 6-year-old female with multiple osteochondroma involving spine presenting as spastic paraplegia is itself rare as males of 2nd decade are mostly affected ...
Archana Meena   +4 more
openaire   +1 more source

Multiple Hereditary Osteochondromas [PDF]

open access: yesMayo Clinic Proceedings, 2019
Lori A, Erickson, Carrie Y, Inwards
openaire   +2 more sources

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