Results 151 to 160 of about 131,340 (225)

Unveiling Endotypes in Systemic Lupus Erythematosus Through Multiomic Analysis: Insights Into Cardiovascular and Renal Complications

Arthritis &Rheumatology, Volume 78, Issue 10, Page 2124-2137, October 2026.
Objective Systemic lupus erythematosus (SLE) shows clinical and molecular heterogeneity, and cardiovascular (CV) complications and lupus nephritis (LN) remain leading causes of morbidity and mortality. This study investigated whether omic profiling can reveal molecular endotypes linked to these outcomes.
Tomás Cerdó, Laurel Woodridge, Sagrario Corrales, Juan Rafael Muñoz‐Castañeda, Ana Isabel Torralbo, Anisur Rahman, Filipa Farinha, Rafaela Ortega Castro, Pedro Segui, Ismael Sanchez‐Pareja, Laura Muñoz‐Barrera, Christian Merlo, Desiree Ruiz‐Vilchez, M. Carmen Ábalos‐Aguilera, Pilar Font, Nuria Barbarroja Puerto, PRECISESADS Clinical Consortium, Lorenzo Beretta, Barbara Vigone, Jacques‐Olivier Pers, Alain Saraux, Valérie Devauchelle‐Pensec, Divi Cornec, Sandrine Jousse‐Joulin, Bernard Lauwerys, Julie Ducreux, Anne‐Lise Maudoux, Carlos Vasconcelos, Ana Tavares, Esmeralda Neves, Raquel Faria, Mariana Brandão, Ana Campar, António Marinho, Fátima Farinha, Isabel Almeida, Miguel Angel Gonzalez‐Gay Mantecón, Ricardo Blanco Alonso, Alfonso Corrales Martínez, Ricard Cervera, Ignasi Rodríguez‐Pintó, Gerard Espinosa, Rik Lories, Ellen De Langhe, Nicolas Hunzelmann, Doreen Belz, Torsten Witte, Niklas Baerlecken, Georg Stummvoll, Michael Zauner, Michaela Lehner, Eduardo Collantes, Ma Carmen Castro‐Villegas, Norberto Ortego, María Concepción Fernández Roldán, Enrique Raya, Inmaculada Jiménez Moleón, Enrique de Ramon, Isabel Díaz Quintero, Pier Luigi Meroni, Maria Gerosa, Tommaso Schioppo, Carolina Artusi, Carlo Chizzolini, Aleksandra Zuber, Donatienne Wynar, Laszló Kovács, Attila Balog, Magdolna Deák, Márta Bocskai, Sonja Dulic, Gabriella Kádár, Falk Hiepe, Velia Gerl, Silvia Thiel, Manuel Rodriguez Maresca, Antonio López‐Berrio, Rocío Aguilar‐Quesada, Héctor Navarro‐Linares, Marta Alarcón‐Riquelme, Alejandro Escudero‐Contreras, M. Ángeles Aguirre‐Zamorano, Carlos Perez‐Sanchez, Elizabeth C. Jury, Chary Lopez‐Pedrera   +84 more
wiley   +1 more source

Genetic kidney disease in adults-the pathologists' perspective. [PDF]

Nephrol Dial Transplant
Paterson AL, Chan MMY, Roufosse C.
europepmc   +1 more source

Unusual Hemodynamic Presentation of Pediatric Kikuchi‐Fujimoto Disease: Persistent Sinus Bradycardia and Vasopressor‐Dependent Hypotension

Clinical Case Reports, Volume 14, Issue 10, October 2026.
ABSTRACT Kikuchi‐Fujimoto disease rarely presents with vasopressor‐dependent hypotension requiring pediatric intensive care despite preserved cardiac function. This case highlights the importance of early excisional lymph node biopsy for timely diagnosis and appropriate management of children with unexplained hemodynamic instability and necrotizing ...
Abdulla Alfraij, Fatma Mothafar, Wasmi Alfadhli, Ali Ashkanani, Lujain A. Kamal, Esmail Redha, Abdulrahman Aldaithan   +6 more
wiley   +1 more source

First case of <i>TREX1</i> mutation-driven retinal vasculopathy with cerebral leukoencephalopathy and systemic manifestations coexisting with lupus nephritis: a case report and mechanistic discussion. [PDF]

Front Immunol
Hao W, Zhai S, Zhu Q, Zhou X, Shen T, He W, Sun Y, Yang W, Yang Y.   +8 more
europepmc   +1 more source

Frequency of Human Brucellosis Complications in West Asia: A Systematic Review and Meta‐Analysis

MicrobiologyOpen, Volume 15, Issue 5, October 2026.
In 51.66% of the included studies in West Asia, the sample size was inadequate for at least half of the complications measured. ABSTRACT Background Brucellosis is a multi‐systemic zoonotic infection. The West Asia/Middle East region is an important global hotspot for brucellosis.
Aliasghar Fakhri‐Demeshghieh, Elnaz Rostamzaman, Fatemeh Sayareh, Amir Nikoukar, Faranak Farahani, Farniya Bakhtiary nia, Helia Sepahvand, Maryam Khaleghi, Mohammadsaeed Azamian, Mohammad Reza Shirzadi, Hesameddin Akbarein, Vahid Rahmanian   +11 more
wiley   +1 more source

Asymptomatic bilateral renal granulomas following intravesical BCG immunotherapy for bladder cancer: a case report. [PDF]

Ann Med Surg (Lond)
Sarfraz M, Qureshi E, Irfan O, Rashid A, Klevay M.   +4 more
europepmc   +1 more source

Mycophenolate mofetil in the treatment of lupus nephritis

, 2008
Patrick FK Yong1,2, David P D&rsquo;Cruz21Department of Clinical Immunology, Kings College Hospital; 2The Lupus Research Unit, St Thomas&rsquo; Hospital, London, UKAbstract: Lupus nephritis is a complication of systemic lupus erythematosus, which
Patrick FK Yong, David P D&rsquo;Cruz   +1 more
core  

Mucosal‐Associated Invariant T Cells in Health and Disease

MedComm, Volume 7, Issue 10, October 2026.
The roles of MAIT cells in health and disease and their therapeutic applications. In healthy individuals, riboflavin metabolites secreted by commensal bacteria at mucosal sites are presented by MR1, leading to the activation of MAIT cells. Activated MAIT cells can maintain the barrier integrity of mucosal tissues in a steady state or migrate to the ...
Yu Zhao, Feng‐Mi Ou, Dan Liang, Yang Gao, Qing‐Qing Li, Yi‐Qun Kuang   +5 more
wiley   +1 more source

Trends, pathological classification of renal diseases proved by biopsy: A 10-year retrospective cohort study in an East Chinese Tertiary Center. [PDF]

Medicine (Baltimore)
Dong R, Sun J, Guo M, Bian Q, Guo Z, Xu J.   +5 more
europepmc   +1 more source

Inflammatory Bowel Disease Is Associated With an Increased Risk of End‐Stage Renal Disease: A Population‐Based Cohort Study

Alimentary Pharmacology &Therapeutics, Volume 64, Issue 8, Page 1110-1122, October 2026.
In a retrospective population‐based cohort study using the University of Manitoba IBD Epidemiology Database, persons with IBD have an increased risk of ESRD by nearly 50%, with CD showing greater risk than UC. Bowel surgery, allopurinol use and oral steroid therapy are important predictors, emphasising the necessity of careful renal monitoring in IBD ...
Onuma Sattayalertyanyong, Zoann Nugent, Bryce Barr, Keevin N. Bernstein, Charles N. Bernstein   +4 more
wiley   +1 more source