Results 51 to 60 of about 13,013 (295)

Addressing Economic Insecurities Can Improve Patient‐Reported Outcomes in Lupus

Arthritis Care &Research, EarlyView.
Objective Economic insecurities, such as food, housing, transportation, and financial challenges, are modifiable risk factors and influence patient‐reported outcomes (PROs) in systemic lupus erythematosus (SLE). We examined the following: (1) associations between economic insecurities and PROs, and (2) the impact of screening and addressing economic ...
Jay Patel, Tripti Singh, Meredith Ingersoll, Shelby Gomez, Amanda Weber, Sarah E. Panzer, Sancia Ferguson, Christie M. Bartels, Shivani Garg   +8 more
wiley   +1 more source

Analysis of the Treatment Efficacy in Late Diagnosis of Alport Syndrome in a Child: Clinical Case

Вопросы современной педиатрии, 2023
Background. Alport syndrome is a systemic, hereditary, progressive disease characterized by ultrastructural changes in the glomerular basement membrane caused by pathogenic variants of type IV collagen genes.
Svetlana Ya. Volgina, Nailya A. Solovyeva, Galina A. Kulakova, Elena A. Kurmayeva, Liliya I. Mukhametdinova, Elina L. Rashitova   +5 more
doaj   +1 more source

Chemokine receptor CCR1: A new target for progressive kidney disease [PDF]

, 2005
Infiltrating leukocytes are thought to contribute to the progression of kidney disease. Locally produced chemokines guide circulating leukocytes into the kidney, which renders therapeutic blockade of respective chemokine receptors on the leukocyte ...
Anders, Hans-Joachim, Ninichuk, Volha
core   +1 more source

Rheumatologic Manifestations of Patients With Type B Insulin Resistance

Arthritis Care &Research, EarlyView.
Objective The objectives of this study were to identify laboratory and clinical features associated with type B insulin resistance (TBIR), a rare condition caused by autoantibodies that inhibit the insulin receptor, most frequently occurring in the setting of systemic lupus erythematosus (SLE), and to increase awareness of this rare, life‐threatening ...
S. Amara Ogbonnaya, Sandra G. Williams, Raphael A. Kirou, Marissa Lightbourne, Rebecca J. Brown   +4 more
wiley   +1 more source

Epidemiology of biopsy‐proven glomerular diseases in Chinese children: A scoping review

Chronic Diseases and Translational Medicine, 2022
Background Glomerular disease is the leading cause of chronic kidney disease globally. No scoping review reports have focused on China's spectrum of glomerular diseases in children.
Yetong Li, Yue Yang, Li Zhuo, Dan Wu, Wenge Li, Xiaorong Liu   +5 more
doaj   +1 more source

Evidence for detrimental cross interactions between reactive oxygen and nitrogen species in Leber's hereditary optic neuropathy cells [PDF]

, 2015
Here we have collected evidence suggesting that chronic changes in the NO homeostasis and the rise of reactive oxygen species bioavailability can contribute to cell dysfunction in Leber’s hereditary optic neuropathy (LHON) patients.We report that ...
Arese, Marzia, Buscarinu, Maria Chiara, Chessa, Luciana, Coarelli, Giulia, Falabella, Micol, Forte, Elena, Giuffre', Alessandro, Magnifico, MARIA CHIARA, Mechelli, Rosella, Radić, Kristina, Salvetti, Marco, Santini, Paolo, Sarti, Paolo   +12 more
core   +4 more sources

Clinical Significance of Therapeutic Drug Level Monitoring for Mycophenolate in Patients With Extrarenal Systemic Lupus Erythematosus—A Systematic Review and Meta‐Analysis

Arthritis Care &Research, EarlyView.
Objective Clinical response to mycophenolic acid (MPA) is highly heterogeneous; thus, therapeutic drug level monitoring (TDM) may help improve treatment efficacy. This systematic review and meta‐analysis examined therapeutic ranges for MPA levels associated with better outcomes and safety in patients with systemic lupus erythematosus (SLE ...
Zahraa Qamhieh, Dalia Sriwi, Callie Saric, Tripti Singh, Christie M. Bartels, Shivani Garg   +5 more
wiley   +1 more source

Apoptosis in renal disease: a brief review of the literature and report of preliminary findings in childhood lupus nephritis

The Turkish Journal of Pediatrics, 2001
Apoptosis, a programmed form of cell death, is an important mechanism that maintains cellular homeostasis. The cellular content of tissues is regulated by a balance between cell proliferation and cell loss.
K Tinaztepe, S Ozen, S Güçer, S Ozdamar   +3 more
doaj  

FGF23-klotho axis as predictive factors of fractures in type 2 diabetics with early chronic kidney disease [PDF]

, 2020
Background: The aim of our study was to evaluate the relevance of FGF23-klotho axis in the predisposition for bone fractures in type 2 diabetic patients with early chronic kidney disease.
Ana Luísa Ribeiro, Ana Paula Silva, Bacchetta, Bernheim, Block, Daya, Desjardins, Ducy, Ducy, Eduarda Carias, Ferron, Filipa Mendes, Fliser, Fátima Rato, Gutiérrez, Hill, Hu, Isakova, Isakova, Jovanovich, Kazama, Lane, Lee, Levey, Manghat, Mirza, Mirza, Moayeri, Moreno, Moseley, Nélio Santos, Pedro Leão Neves, Pi, Pinkau, Qu, Quarles, Ray, Sanches, Sellmeyer, Shimada, Silva, Silva, Silva, Sitara, Stubbs, Titan, Torres, Urakawa, Wallace, Wang, Wolf, Yilmaz, Zimering   +52 more
core   +1 more source

Developing and Evaluating a Laboratory‐Based Frailty Index (FI‐Lab) for the Prediction of Long‐Term Health Outcomes in Systemic Lupus Erythematosus

Arthritis Care &Research, Accepted Article.
Objective We aimed to construct and evaluate the first laboratory‐based frailty index (FI‐Lab) for predicting adverse outcomes in systemic lupus erythematosus (SLE) and to compare its predictive ability to that of an existing clinical frailty index (FI).
Grace Burns, Samuel D. Searle, Alexandra Legge   +2 more
wiley   +1 more source