Results 171 to 180 of about 730,614 (221)

Duagnosis: Locating Clinical Uncertainty in the Diagnostic Framework

Journal of Evaluation in Clinical Practice, Volume 32, Issue 6, September 2026.
ABSTRACT Rationale, Aims and Objectives Clinical reasoning research has predominantly operated within a single epistemological system. The prevailing response to clinical uncertainty in primary care has been to cultivate tolerance, embrace ambiguity, or learn to navigate it: each treats uncertainty as inherent to the encounter.
Kosei Hanaoka, Daisuke Miyamori, Keiko Ogawa‐Ochiai   +2 more
wiley   +1 more source

Boy in the Barrel: Excruciating Paroxysmal Pain Disorder Associated With an SCN9A Gain‐of‐Function Variant

Journal of the Peripheral Nervous System, Volume 31, Issue 3, September 2026.
ABSTRACT Background and Aims Gain‐of‐function variants in SCN9A, encoding the Nav1.7 sodium channel, cause inherited painful neuropathic disorders. We report a young man with severe childhood‐onset heat‐triggered paroxysmal pain, autonomic dysfunction, skeletal abnormalities, and a de novo SCN9A p.Ile234Thr variant, emphasizing the diagnostic and ...
Pedro Jose Tomaselli, Rodrigo Siqueira Soares Frezatti, Christopher J. Record, Maria Cristina Lopes Schiavoni, Natalia Dominik, Jana Vandrovcova, Mary M. Reilly, Wilson Marques Jr   +7 more
wiley   +1 more source

Neuropathy predicts early renal impairment in diabetes mellitus-the almost forgotten historical evidence. In memoriam Professor Göran Sundkvist. [PDF]

Front Clin Diabetes Healthc
Kempler P, Balogh DM, Horváth VJ, Menyhárt A, Rizzo M, Tesfaye S, Spallone V.   +6 more
europepmc   +1 more source

The Burden of Small Fiber Neuropathy: Changes in Pain, Costs, and Quality of Life Before and After Diagnosis

Journal of the Peripheral Nervous System, Volume 31, Issue 3, September 2026.
ABSTRACT Background and Aims Small fiber neuropathy (SFN) is a peripheral neuropathy causing neuropathic pain, reduced quality of life (QoL), and high societal costs. Previous studies assessed these societal costs before a definitive diagnosis was established, leaving it unclear whether diagnostic confirmation affects costs, pain intensity, or QoL ...
Dennis Kool, Margot Geerts, Lloyd Brandts, Merel Kimman, Caroline M. L. Gorissen‐Brouwers, Catharina G. Faber, Ingemar S. J. Merkies, Janneke G. J. Hoeijmakers   +7 more
wiley   +1 more source

Broadening the Clinical Spectrum of Axonal Hereditary Neuropathies: A Comparative Case Study on DNAJB2- and HINT1-Related Disease. [PDF]

J Peripher Nerv Syst
Bjelica B, Hendrich C, von Hardenberg S, Vukojevic M, Körner S, Gschwendtberger T, Haghikia A, Peric S, Petri S.   +8 more
europepmc   +1 more source

Clinical features of systemic amyloidosis: a scoping review. [PDF]

Blood Adv
Cook J, Shaikh H, Azzam M, Aguirre MA, Boedicker DD, Carroll AS, Dasgupta N, De la Torre A, Jamal F, Khouri J, Raza S, Sarswat N, Kawtharany H, Seftel M, Mustafa RA, Kukreti V.   +15 more
europepmc   +1 more source

Insights Into Self‐Care of Feet When Living With Diabetes: A Phenomenological Hermeneutic Interview Study

Journal of Clinical Nursing, Volume 35, Issue 9, Page 3912-3920, September 2026.
ABSTRACT Aim To describe how persons with diabetes experience learning about self‐care, with a particular focus on foot self‐care. Methods Narrative, semi‐structured interviews were conducted with persons diagnosed with Type 1 or Type 2 diabetes.
Kristofer Björk, Henrik Eriksson, Ulla Hellstrand Tang, Susanne Andersson   +3 more
wiley   +1 more source

Assessment of Chemotherapy-Induced Peripheral Neuropathy and Its Relationship to Breast Cancer Patients' Quality of Life. [PDF]

Maedica (Bucur)
Hakeem F.
europepmc   +1 more source

Physiologically‐Guided Ultrafiltration: A Proposed Ultrasound Framework for Individualized Volume Removal During Hemodialysis

Nephrology, Volume 31, Issue 9, September 2026.
ABSTRACT Ultrafiltration during hemodialysis is the most hemodynamically stressful intervention dialysis patients endure, yet its prescription relies on interdialytic weight gain and clinical gestalt. Rates exceeding 13 mL/kg/h carry substantially higher cardiovascular mortality, and recurrent intradialytic hypotension drives myocardial stunning ...
Sharad Patel, Arwa Bootwala, Adam Green
wiley   +1 more source

Amyloidosis & Advanced Heart Failure: When to Consider Cardiac Transplantation and What are the Results? [PDF]

Curr Heart Fail Rep
Hamilton S, Patolia H, Hanna M.
europepmc   +1 more source