Results 191 to 200 of about 219,352 (339)
Biological Reviews, EarlyView.ABSTRACT Three categories of explanations exist for why we age: mechanistic theories, which omit reference to evolutionary forces; weakening force of selection theories, which posit that barriers exist that prevent evolutionary forces from optimising fitness in ageing; and optimisation theories, which posit that evolutionary forces actually select for ...
Michael S. Ringel
wiley +1 more source
Knowledge, attitudes and practices of cancer genetics in family medicine in Japan: a mixed methods study. [PDF]
BMC Prim CareNarumoto K +5 more
europepmc +1 more source
The power of many: when genetics met yeasts and high‐throughput
Biological Reviews, EarlyView.ABSTRACT In recent years, complex technological capabilities have evolved, driven by the need to solve complex and integrative biological questions through global analyses. New equipment allows the scaling up and automation of processes which previously were carried out on a very limited scale.
Víctor A. Tallada, Víctor Carranco
wiley +1 more source
STUDIES IN MICROBIC HEREDITY II. THE SEXUAL CYCLE OF B. COLI IN RELATION TO THE ORIGIN OF VARIANTS WITH SPECIAL REFERENCE TO NEISSER AND MASSINI'S B. COLI-MUTABILE [PDF]
, 1925 R. R. Mellon
openalex +1 more source
Chiari I Malformation: Review and Update of Current Treatment Options
Clinical Anatomy, EarlyView.ABSTRACT The pathophysiology of Chiari malformation type I (CM‐I) is complex, involving structural abnormalities at the craniovertebral junction that result in herniation of the cerebellar tonsils through the foramen magnum. In this study, we aim to present and evaluate current treatment options for CM‐I, with a focus on evidence‐based clinical ...
Jordan J. Lo +11 more
wiley +1 more source
My risk perception; perspectives from youth at familial risk for bipolar disorder: a qualitative study. [PDF]
BMC PsychiatryAhmed Y +4 more
europepmc +1 more source
Protocol for Reconstituting Adaptor‐Mediated Activation of Full‐Length Kinesin‐1
Cytoskeleton, EarlyView.ABSTRACT Kinesin‐1 is a member of the kinesin superfamily that plays an essential role in intracellular cargo transport. In the absence of cargo, Kinesin‐1 exhibits low motor activity due to autoinhibition. Multiple studies have demonstrated that adaptor proteins, which link cargos to Kinesin‐1, can activate Kinesin‐1 by releasing the autoinhibition ...
Haruka Masumoto, Kyoko Chiba
wiley +1 more source
The cancer genome and the birth of precision medicine. [PDF]
HaematologicaDiPersio JF.
europepmc +1 more source