Results 81 to 90 of about 219,352 (339)

HEREDITY AND ENVIRONMENT AS DETERMINING FACTORS IN THE GAME OF WATER POLO

open access: gold, 2023
Costel Matei   +41 more
openalex   +1 more source

Allosteric Modulation of Pathological Ataxin‐3 Aggregation: A Path to Spinocerebellar Ataxia Type‐3 Therapies

open access: yesAdvanced Science, EarlyView.
This study uncovers a new allosteric site in the Josephin domain of ataxin‐3 targeted by the molecular tweezer CLR01, which modulates protein aggregation, improves synaptic function in neuronal cells, and delays motor dysfunction in animal models.
Alexandra Silva   +28 more
wiley   +1 more source

Lifestyle changes in descendants of parents with diabetes type 2 Cambio en los patrones de vida en descendientes de progenitores con diabetes mellitus tipo 2 del noreste de Mexico Mudança em os padrões de vida em descendentes de progenitores com diabetes mellitus tipo 2 do nordeste do México

open access: yesRevista Latino-Americana de Enfermagem, 2007
This study aimed to explore the disposition of diabetic parents' descendents in changing eating and physical activity patterns. It was based on the heritability concept and Prochaska's Transtheoretical Model.
Rosalinda Guerra-Juárez   +2 more
doaj   +1 more source

XIAP Stabilizes DDRGK1 to Promote ER‐Phagy and Protects Against Noise‐Induced Hearing Loss

open access: yesAdvanced Science, EarlyView.
Mechanism of GAS‐mediated protection against noise‐induced hearing loss (NIHL). Noise exposure activates the ATF4/eIF2α axis, downregulating XIAP and promoting DDRGK1 degradation, thereby inhibiting ER‐phagy and leading to hair cell (HC) death. GAS treatment rescues XIAP and DDRGK1 expression, reactivating ER‐phagy to mitigate HC loss, synaptic damage,
Lin Yan   +13 more
wiley   +1 more source

A prospective pilot study on DACHAO intervention for improving embryo quality metrics in IVF/ICSI failure cases

open access: yesFrontiers in Cell and Developmental Biology
Research questionEmbryo quality serves as a pivotal determinant in assisted reproductive technology (ART) outcomes, with high-grade embryos correlating with improved pregnancy/live birth rates but poor morphology elevating the risks of implantation ...
Rui Xing   +23 more
doaj   +1 more source

Lattices of choice functions and consensus problems [PDF]

open access: yes
. In this paper we consider the three classes of choice functionssatisfying the three significant axioms called heredity (H), concordance (C) and outcast (O).
Bernard Monjardet   +1 more
core  

On heredity of strongly proximal actions [PDF]

open access: yes, 2003
We prove that action of a semigroup T on compact metric space X by continuous selfmaps is strongly proximal if and only if T action on P(X), the space of probability measures on $X$ with weak topology, is strongly proximal. As a consequence we prove that
Raja, C. R. E.
core   +1 more source

Selective Targeting of Tip Endothelial Cells as a Therapeutic Strategy for Tumor Angiogenesis

open access: yesAdvanced Science, EarlyView.
Doppel protein is selectively expressed in tip endothelial cells within the tumor vasculature, where it promotes tip cell motility and stabilizes the tip cell phenotype. Targeting Doppel with monoclonal antibodies disrupts this stabilization, impairs angiogenic sprouting, and reduces tumor angiogenesis, offering a selective and druggable switch for ...
Byoungmo Kim   +16 more
wiley   +1 more source

THE ROLE OF THE HEREDITARY PREDISPOSITION IN THE DEVELOPMENT OF AORTA COARCTATION

open access: yesВопросы современной педиатрии, 2012
As a result of examination of the families of patients with aorta coarctation the factors predisposing to this condition were established. Sixty eight patients with different localization, stenosis degree and extent of aorta coarctation were included ...
T. N. Tatarinova   +3 more
doaj   +1 more source

A comparative study on accounting heredity: the case of ex soviet countries versus other eastern european countries [PDF]

open access: yes
This paper aims at investigating the existence of accounting heredity in some of Eastern European countries. Accounting heredity assumes that at the time the economic paradigm changes, a new accounting system emerges, enclosing both genes from the ...
Artemisa Calu Daniela   +4 more
core  

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