Results 81 to 90 of about 238,041 (341)

Genetic, epigenetic and exogenetic information [PDF]

open access: yes, 2017
We describe an approach to measuring biological information where ‘information’ is understood in the sense found in Francis Crick’s foundational contributions to molecular biology.
Griffiths, Paul Edmund, Stotz, Karola
core  

Hierarchical adaptive polynomial chaos expansions

open access: yes, 2015
Polynomial chaos expansions (PCE) are widely used in the framework of uncertainty quantification. However, when dealing with high dimensional complex problems, challenging issues need to be faced.
Mai, Chu V., Sudret, Bruno
core   +1 more source

The case of Heinrich Wilhelm Poll (1877-1939): A German-Jewish geneticist, eugenicist, twin researcher, and victim of the Nazis [PDF]

open access: yes, 2006
This paper uses a reconstruction of the life and career of Heinrich Poll as a window into developments and professional relationships in the biological sciences in Germany in the period from the beginning of the twentieth century to the Nazi seizure of ...
Braund, James, Sutton, Douglas G.
core   +1 more source

Innate Immune Reprogramming Mediated by Endogenous Retroelement Dysregulation Drives Multiple Sclerosis Progression

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
Epigenetic reprogramming in hematopoietic stem and progenitor cells (HSPCs) and downstream myeloid cells, mediated by H3.3 downregulation and endogenous retroelement (ERE) overexpression, contributes to the progression of multiple sclerosis (MS). ABSTRACT Background Skewed myelopoiesis in the bone marrow has been identified as a key driver of multiple ...
Li‐Mei Xiao   +6 more
wiley   +1 more source

Transmission maternelle en Grèce ancienne : du physique au comportement

open access: yesCahiers Mondes Anciens, 2015
My paper will examine a variety of sources (medical and biological texts, tragedy and comedy, forensic rhetoric, poetry), in order to consider and reassess the role of the mother in the construction of child-identity in the ancient Greek world ...
Florence Gherchanoc
doaj   +1 more source

Extending the Modern Synthesis: The evolution of ecosystems [PDF]

open access: yes, 2010
The Modern Evolutionary Synthesis formalizes the role of variation, heredity, differential reproduction and mutation in population genetics. Here we explore a mathematical structure, based on the asymptotic limit theorems of information theory, that ...
Rodrick Wallace
core   +2 more sources

THE PROBLEM OF HEREDITY. [PDF]

open access: yesJAMA: The Journal of the American Medical Association, 1902
The individual who comes into the world is, as Luys1remarks, not an isolated being separated from his kindred. He is one link in a long chain which is unrolled by time, and of which the first links are lost in the past. He is bound to those who follow him and to the atavic influence which he possesses; he serves for their temporary resting place, and ...
openaire   +1 more source

SPG4 and Dementia: Expanding the Clinical Spectrum

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza   +19 more
wiley   +1 more source

Association of sperm DNA fragmentation index with semen quality and ART outcomes: real-world evidence from a retrospective cohort

open access: yesBasic and Clinical Andrology
Background Sperm DNA fragmentation index (DFI) has emerged as a potential marker of male fertility, but its clinical value in assisted reproductive technology (ART) remains debated.
Chaofeng Wei   +7 more
doaj   +1 more source

Active causation and the origin of meaning [PDF]

open access: yes, 2014
Purpose and meaning are necessary concepts for understanding mind and culture, but appear to be absent from the physical world and are not part of the explanatory framework of the natural sciences.
van Hateren, J. H.
core   +2 more sources

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