Results 191 to 200 of about 236,259 (268)

Single‐nucleotide polymorphisms in coronary artery disease: Biological complexity, risk architecture, and implications for precision prevention

Precision Medical Sciences, EarlyView.
This graphical summary highlights the clinical application of single‐nucleotide polymorphisms‐based risk stratification in coronary artery disease. By integrating polygenic risk with clinical assessment, imaging, and preventive strategies, genetic information enables earlier risk identification, optimized screening, and personalized lifestyle and ...
Li Dai, Mosi Chen, Jun Hu, Lei Huang, Ye Yang, Chang Chen, Ying Zhuang, Yan Pan, Bingjun Qian   +8 more
wiley   +1 more source

Computation and resource efficient genome-wide association analysis for large-scale imaging studies. [PDF]

Nat Commun
Jiang Z, Stein J, Li T, Fang E, Li Y, Sullivan P, Zhu H.   +6 more
europepmc   +1 more source

Larval antibiosis to cabbage stem flea beetle (Psylliodes chrysocephala) is absent within oilseed rape (Brassica napus)

Pest Management Science, EarlyView.
We screened a panel of 98 Brassicaceae genotypes (97 Brassica napus and 1 Sinapis alba) for cabbage stem flea beetle (Psylliodes chrysocephala) larval antibiosis. We found limited evidence for antibiosis across B. napus but consistent antibiosis in S. alba. Brassicaceae relatives may therefore better inform resistance traits for breeding.
Ryan E Brock, Clara Courtney, Steven Penfield, Rachel Wells   +3 more
wiley   +1 more source

Harnessing Natural Compounds in Psoriasis: Targeting Cellular Pathways for Effective Therapy

Phytotherapy Research, EarlyView.
Natural compounds act on key cellular pathways in psoriasis by suppressing keratinocyte hyperproliferation, modulating Th17/IL‐17‐mediated immune responses, and reducing oxidative stress. These multi‐target effects highlight their potential as safer adjunctive therapies alongside conventional treatments.
Hye Jin Lee, Yu Jin So, Il‐Joo Jo, Ji Yong Jang, Tae Han Yook, Jun Ho Lee, Sung Wook Kim, Kangwook Lee, Soo Jung Park, Gabsik Yang   +9 more
wiley   +1 more source

Genetic Parameters for Rumination Time, Daily Average Milk Temperature, and Milking Traits Derived from Automatic Milking Systems in Holstein Cattle. [PDF]

Animals (Basel)
Altınsoy A, Altınsoy HY, Duru S, Filya İ.   +3 more
europepmc   +1 more source

Construction of an O2‐responsive engineering bioreactor for enhanced indole‐3‐propionic acid production and deoxynivalenol detoxification

Responsive Materials, EarlyView.
An oxygen‐responsive living bioreactor was engineered via interspecies protoplast fusion, converting oxygen from an inhibitory stress into a programmable signal for sustained indole‐3‐propionic acid (IPA) production. This genetically encoded bioreactor enables robust aerobic operation and therapeutic efficacy of deoxynivalenol detoxification in vivo ...
Ning Ma, Jiakun Shen, Kun Cai, Wenxi Zhao, Chuan Feng, Xingyao Wang, Yangyang Liu, Dongyan Zhang, Xi Ma   +8 more
wiley   +1 more source

Research note: Comparative estimation of genetic parameters for eggshell pigmentation traits. [PDF]

Poult Sci
Wang R, Lai J, Jin H, Luo B, Zheng C, Mao Z, Xu G, Zheng J.   +7 more
europepmc   +1 more source

Prevalence of hip and elbow dysplasia in young adult dogs in Sweden

Veterinary Record, EarlyView.
Abstract Background Hip and elbow dysplasia (HD and ED) are common developmental orthopaedic disorders in dogs. The study objectives were to report population‐based estimates of HD and ED prevalence at screening in young adult dogs of different breeds and to evaluate the phenotypic association between HD and ED.
Karolina Engdahl, Sofia Malm Persson, Linda Andersson, Sara Ringmark, Charlotte Reinhard Bjørnvad, Åke Hedhammar, Katja Höglund   +6 more
wiley   +1 more source

The role of <i>trans</i>-acting factors in the pathogenesis of common psychiatric disorders. [PDF]

Epigenetics
Peedicayil J, Grayson DR.
europepmc   +1 more source

Nests in trees are as good as or better than cliffs for two formerly persecuted, primarily cliff nesting eagles in Spain: a cautionary tale in defining the habitat of range‐restricted or threatened species

Wildlife Biology, EarlyView.
In the late‐20th century, golden and Bonelli's eagles suffered population declines on the Iberian Peninsula, partly due to human persecution. Habitat assessments – especially for Bonelli's eagles – always found or assumed strong associations with cliffs that provided nesting sites.
Ryan Baumbusch, Jesus Bautista, Jose Rafael Garrido, Ian Newton, Miguel Ferrer, Virginia Morandini   +5 more
wiley   +1 more source