Results 51 to 60 of about 103,874 (191)

Direct Estimates of the Genomic Contributions to Blood Pressure Heritability within a Population-Based Cohort (ARIC). [PDF]

PLoS ONE, 2015
Blood pressure (BP) is a heritable trait with multiple environmental and genetic contributions, with current heritability estimates from twin and family studies being ~ 40%.
Elias Salfati, Alanna C Morrison, Eric Boerwinkle, Aravinda Chakravarti   +3 more
doaj   +1 more source

SNP-based and pedigree-based estimation of heritability and maternal effect for body weight traits in an F2 intercross between Landrace and Jeju native black pigs

Journal of Animal Reproduction and Biotechnology, 2016
Growth traits, such as body weight, directly influence productivity and economic efficiency in the swine industry. In this study, we estimate heritability for body weight traits usinginformation from pedigree and genome-wide single nucleotide ...
Hee-Bok Park, Sang-Hyun Han, Jae-Bong Lee, Sang-Geum Kim, Yong-Jun Kang, Hyun-Sook Shin, Sang-Min Shin, Ji-Hyang Kim, Jun-Kyu Son, Kwang-Soo Baek, Sang-Rae Cho, In-Cheol Cho   +11 more
doaj   +1 more source

Heritability estimates of body size in fetal life and early childhood.

PLoS ONE, 2012
BackgroundThe objective was to estimate the heritability for height and weight during fetal life and early childhood in two independent studies, one including parent and singleton offsprings and one of mono- and dizygotic twins.MethodsThis study was ...
Dennis O Mook-Kanamori, Catharina E M van Beijsterveldt, Eric A P Steegers, Yurii S Aulchenko, Hein Raat, Albert Hofman, Paul H Eilers, Dorret I Boomsma, Vincent W V Jaddoe   +8 more
doaj   +1 more source

Relative abundance data can misrepresent heritability of the microbiome

Microbiome, 2023
Background Host genetics can shape microbiome composition, but to what extent it does, remains unclear. Like any other complex trait, this important question can be addressed by estimating the heritability (h 2 ) of the microbiome—the proportion of ...
Marjolein Bruijning, Julien F. Ayroles, Lucas P. Henry, Britt Koskella, Kyle M. Meyer, C. Jessica E. Metcalf   +5 more
doaj   +1 more source

Estimation of heritability and genetic advance for various metric traits in seven F2 populations of bread wheat (Triticum aestivum L.) [PDF]

Journal of Agricultural Sciences (Belgrade), 2016
Heritability estimates provide information about the traits that are transmitted from parents to their offsprings and it has a crucial role in selection criteria to improve grain yield.
Saleem Babar, Khan Abdus Salam, Shahzad Muhammad Talha, Ijaz Fahid   +3 more
doaj   +1 more source

Heritability in frontotemporal tauopathies

Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, 2019
Introduction Exploring the degree of heritability in a large cohort of frontotemporal lobar degeneration with tau‐immunopositive inclusions (FTLD‐tau) and determining if different FTLD‐tau subtypes are associated with stronger heritability will provide ...
Shelley L. Forrest, Glenda M. Halliday, Heather McCann, Andrew B. McGeachie, Ciara V. McGinley, John R. Hodges, Olivier Piguet, John B. Kwok, Maria G. Spillantini, Jillian J. Kril   +9 more
doaj   +1 more source

High heritability is compatible with the broad distribution of set point viral load in HIV carriers.

PLoS Pathogens, 2015
Set point viral load in HIV patients ranges over several orders of magnitude and is a key determinant of disease progression in HIV. A number of recent studies have reported high heritability of set point viral load implying that viral genetic factors ...
Sebastian Bonhoeffer, Christophe Fraser, Gabriel E Leventhal   +2 more
doaj   +1 more source

SNP-based heritability estimation using a Bayesian approach

Animal, 2013
Heritability is a central element in quantitative genetics. New molecular markers to assess genetic variance and heritability are continually under development. The availability of molecular single nucleotide polymorphism (SNP) markers can be applied for
K. Krag, L.L. Janss, M.M. Shariati, P. Berg, A.J. Buitenhuis   +4 more
doaj   +1 more source

Reliable heritability estimation using sparse regularization in ultrahigh dimensional genome-wide association studies

BMC Bioinformatics, 2019
Background Data from genome-wide association studies (GWASs) have been used to estimate the heritability of human complex traits in recent years. Existing methods are based on the linear mixed model, with the assumption that the genetic effects are ...
Xin Li, Dongya Wu, Yue Cui, Bing Liu, Henrik Walter, Gunter Schumann, Chong Li, Tianzi Jiang   +7 more
doaj   +1 more source

The Heritable Effects of Nanotoxicity

Nanomedicine, 2014
The widespread entry of nanomaterials into manifold life fields posed serious concerns on environmental health and safety issues. Potential adverse effects of nanoparticles (NPs) are continuously faced using in vitro cell systems and by mean of cell and molecular biology tools, several mechanisms have been found beyond their toxicity. The evaluation of
Tortiglione, Claudia
openaire   +4 more sources