Results 21 to 30 of about 62,040 (267)

Long‐Term Outcomes After Stoma Creation in Crohn's Disease: A Retrospective Cohort Study of 422 Patients

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
ABSTRACT Aim Stoma creation is often required in Crohn's disease (CD), most commonly because of progressive anorectal disease. As stoma closure strongly influences long‐term quality of life and surgical decision‐making, this study evaluated the indications and long‐term outcomes of stoma creation in patients with CD.
Kentaro Nagano   +9 more
wiley   +1 more source

The prognostic role of palliative gastrectomy in advanced gastric cancer: a systematic review and meta-analysis

open access: yesBMC Cancer
Background The effectiveness of palliative gastrectomy for advanced GC remains a topic of debate. This study sought to establish whether palliative gastrectomy has an impact on prolonging survival.
Desheng Luo   +7 more
doaj   +1 more source

Long‐Term Follow Up of Two Patients With Variants in the Cluster 1031‐1159 of TRRAP Gene: Expanding the Phenotype of Developmental Delay With or Without Dysmorphic Facies and Autism

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT The transformation/transcription domain‐associated protein (TRRAP) gene encodes a large multidomain protein, a member of the phosphatidylinositol 3‐kinase‐related kinase (PIKK) family. TRRAP is a component of the histone acetyltransferase (HAT) complex, and it plays an important role in gene transcription, DNA repair, and cell‐cycle regulation.
Roseli Maria Zechi‐Ceide   +10 more
wiley   +1 more source

The management of recurrent hiatal hernia: a single-center retrospective study

open access: yesBMC Surgery
Purpose Hiatal hernia (HH), characterized by gastric mucosa displacement > 2 cm above the diaphragm, presents significant challenges with recurrence rates ranging from 10 to 60%.
Minxian Zhao   +7 more
doaj   +1 more source

Clinical Outcomes and Patient Experiences With Celiprolol Therapy in Vascular Ehlers–Danlos Syndrome: The First Non‐European Cohort

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Vascular Ehlers–Danlos syndrome (vEDS) is a hereditary connective tissue disorder caused by heterozygous pathogenic variants in COL3A1. European studies have shown that celiprolol may reduce the risk of life‐threatening vascular events, but outcomes in non‐European populations and the therapy's psychological impact remain unclear. We conducted
Megumi Furuhata‐Yoshimura   +2 more
wiley   +1 more source

Surgical methods and outcomes of inguinal hernia repair in children, adolescents and young adults in a retrospective cohort study

open access: yesScientific Reports
Laparoscopic repair as an alternative option for pediatric inguinal hernia has increased worldwide. We aimed to analyze the surgical methods of inguinal hernia repair among children, adolescents and young adults, and evaluate the surgical outcomes of ...
Qiuyue Ma   +6 more
doaj   +1 more source

Co‐Occurring Non‐Cardiac Congenital Anomalies Among Cases With Congenital Heart Defects

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Cases with congenital heart defects (CHD) often have other associated anomalies. The aim of this investigation was to assess the prevalence and the types of co‐occurring anomalies in CHD in a well‐defined population. The anomalies co‐occurring with CHD were ascertained in all live births, stillbirths and terminations of pregnancy for fetal ...
Claude Stoll   +2 more
wiley   +1 more source

Anatomic All‐Epiphyseal Anterior Cruciate Ligament Reconstruction With Concomitant Lateral Extra‐articular Tenodesis Using Iliotibial Band Autograft

open access: yesArthroscopy Techniques, EarlyView.
Abstract Anterior cruciate ligament rupture is increasingly common in skeletally immature patients. The Micheli‐Kocher iliotibial band technique is physeal‐sparing, but nonanatomic, whereas all‐epiphyseal reconstructions reproduce the anterior cruciate ligament footprint but lack lateral support. We describe an anatomic all‐epiphyseal anterior cruciate
Jordan T. Holler   +2 more
wiley   +1 more source

Geriatric nutritional risk index as a predictor of major postoperative complications in emergency femoral hernia patients

open access: yesBMC Surgery
Background To evaluate the prognostic values of GNRI for major postoperative complications in emergency femoral hernia patients. Methods In this cross-sectional study, we enrolled 105 emergency femoral hernia patients.
Qiuyue Ma   +5 more
doaj   +1 more source

Novel insights into biomarkers of progression in Desmoid tumor

open access: yesFrontiers in Oncology, 2023
Desmoid tumor (DT) is a rare neoplasm characterized by the proliferation of myofibroblastic cells that infiltrates and invades adjacent tissues. Due to its locally aggressive and recurrent nature, DT often causes local symptoms and can be challenging to ...
Baiqi Liu   +12 more
doaj   +1 more source

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