Results 231 to 240 of about 169,399 (309)

Off‐midline versus supraumbilical specimen extraction sites in robot‐assisted radical prostatectomy

open access: yesBJU International, EarlyView.
Objectives To compare two different specimen extraction sites (SES) (off‐midline [OM] vs. supraumbilical) for the incidence of incisional hernias (IHs) and to evaluate different risk factors for their occurrence after robot‐assisted radical prostatectomy.
Jonathan Vollemaere   +9 more
wiley   +1 more source

Small-bowel incarceration and perforation through a hernia defect associated with a pubic fracture: a case report. [PDF]

open access: yesAnn Med Surg (Lond)
Kume T   +6 more
europepmc   +1 more source

Novel approaches for drug development against chronic primary pain: A systematic review

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus   +5 more
wiley   +1 more source

Genetics in Heterotaxy: A Case Series and Literature Review on DNAH9, PKD1L1, MMP21, and GDF1

open access: yesClinical Genetics, EarlyView.
Integrating trio‐based genomic sequencing with detailed clinical evaluation across seven French–Vietnamese heterotaxy cases alongside a review of 108 published patients reveals strong genotype–phenotype correlations. Variants in DNAH9, PKD1L1, MMP21, and GDF1 define a broad spectrum from isolated situs inversus to complex conotruncal heart defects and ...
Thi Bich Tuyen Ho   +23 more
wiley   +1 more source

Surviving Males With PORCN Variants: Expanding the Clinical, Molecular, and Mechanistic Spectrum

open access: yesClinical Genetics, EarlyView.
Pathogenic PORCN variants are compatible with male survival in both mosaic and non‐mosaic states, expanding the FDH/PONGOS spectrum and improving diagnosis and genetic counseling. ABSTRACT Pathogenic variants in PORCN cause focal dermal hypoplasia (FDH/Goltz syndrome), an X‐linked dominant disorder historically considered lethal in males, with milder ...
Lucía Miranda‐Alcaraz   +23 more
wiley   +1 more source

Clinics in diagnostic imaging (226). [PDF]

open access: yesSingapore Med J
Yap HW, Lam JJH, Teo F.
europepmc   +1 more source

Macrophage Lipid Homeostasis Drives IVDD via a Senescence‐Dependent Impairment of Efferocytosis

open access: yesCell Proliferation, EarlyView.
Intervertebral disc degeneration (IVDD) has been a leading cause of low back pain and lacks disease‐modifying therapies. Although dysregulated disc lipid metabolism is implicated, its impact on the immune microenvironment, particularly macrophages, remains unknown.
Jinyu Wang   +12 more
wiley   +1 more source

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