Results 261 to 270 of about 300,155 (312)

BRD4/MAP2K7/PGF Signaling Axis Promotes Senescence and Extracellular Matrix Metabolism of Nucleus Pulposus Cells in Intervertebral Disk Degeneration

open access: yesAging Cell, EarlyView.
This study identifies BRD4 as a key regulator in intervertebral disk degeneration (IDD), linking its upregulation to NP cell senescence and disrupted ECM metabolism through the BRD4/MAP2K7/PGF signaling cascade, offering a potential therapeutic target for IDD treatment.
Guangzhi Zhang   +6 more
wiley   +1 more source

Epidemiology of diagnostic errors in pediatric emergency departments using electronic triggers

open access: yesAcademic Emergency Medicine, Volume 32, Issue 3, Page 226-245, March 2025.
Abstract Objectives We applied three electronic triggers to study frequency and contributory factors of missed opportunities for improving diagnosis (MOIDs) in pediatric emergency departments (EDs): return visits within 10 days resulting in admission (Trigger 1), care escalation within 24 h of ED presentation (Trigger 2), and death within 24 h of ED ...
Prashant Mahajan   +18 more
wiley   +1 more source

Obstructive sleep apnoea, sleep bruxism and gastroesophageal reflux – mutually interacting conditions? A literature review

open access: yesAustralian Dental Journal, Volume 69, Issue S1, Page S38-S44, June 2024.
Abstract The purpose of the present manuscript is to provide an overview for researchers and clinicians summarizing the knowledge concerning the relationship between some of the main sleep‐related conditions of dental interest: sleep bruxism (SB), obstructive sleep apnoea (OSA) and gastroesophageal reflux disease (GERD). Starting with the discussion of
Davis C. Thomas   +2 more
wiley   +1 more source

Follow-up of complex hernia repair with intraoperative fascial traction. [PDF]

open access: yesHernia
Woeste G   +8 more
europepmc   +1 more source

Detection of germ cell neoplasia in situ and testicular cancer risk in men with testicular microlithiasis: Real world results through 10 years

open access: yesAndrology, EarlyView.
Abstract Background Guidelines recommend biopsies for men <50 years with testicular microlithiasis and cancer risk factors to rule out germ cell neoplasia in situ. Limited data support this practice. Objectives To clarify the significance of testicular microlithiasis by examining pathological findings in men with testicular microlithiasis.
Karoline Skov Lundager   +7 more
wiley   +1 more source

Left-Sided Amyand's Hernia Managed Without Appendectomy: A Case Report of a Rare Diagnosis. [PDF]

open access: yesCureus
da Silva Balo LM   +4 more
europepmc   +1 more source

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