Results 41 to 50 of about 68,126 (243)

Giant pedunculated incisional hernia

Annals of African Medicine, 2020
Ventral hernia is a common complication of abdominal surgeries, with the incidence of up to 20% in some series. Giant ventral hernia is that with a neck more than 10 cm wide. The loss of abdominal domain due to the shift of viscera into the hernia sac could lead to the complication after surgery. A 54-year-old female presented with a giant pedunculated
Abuabakar, Amina I., Miner, Elijah N.
openaire   +3 more sources

Fumarate Hydratase Lactylation Exacerbates Traumatic Brain Injury Pathology via Mitochondrial Dysfunction and Neuroinflammation

Advanced Science, EarlyView.
Tian et al. reveal that FH K112 lactylation is elevated after TBI, leading to fumarate accumulation, mitochondrial damage, mtDNA release and amplified neuroinflammation. AARS2 and SIRT3 act as the “writer” and “eraser” for FH K112 lactylation. The peptide Pep‐K112 targeting this site alleviates brain injury, highlighting a potential therapeutic target.
Yang Tian, Shuoyao Ma, Bo Yang, Fei Gao, Hao Guo, Haixiao Liu, Xun Wu, Wenxing Cui, Jingyu Dong, Qian Lin, Yufeng Ge, Jin Ma, Jiazhen Zhao, Yongzhi Zhang, Dongzhi Xue, Jiaxin Tian, Ziwen Zhang, Kai Wang, Meng Xu, Dayun Feng, Jinpeng Zhou, Yan Qu   +21 more
wiley   +1 more source

ROS‐Responsive Nanoparticle Delivery of Dexmedetomidine Protects the Gut Vascular Barrier After Intestinal Ischemia/Reperfusion via the HDAC‐H3K27ac‐TCF4 Axis

Advanced Science, EarlyView.
A low dose of dexmedetomidine, delivered by ROS‐responsive nanoparticles, preferentially accumulates in the ischemic intestine and restores gut vascular barrier integrity after ischemia/reperfusion injury. This nanoparticle‐based strategy prevents bacterial translocation and liver damage without cardiorespiratory side effects, working through HDAC ...
Hu‐Fei Zhang, Jian‐Tong Shen, Hua‐Hua Zhang, Si‐Qi Gao, Ji‐Ao Wang, Yue‐Ling Wang, Mei‐Ling Li, Zi‐Meng Liu, Yi‐Nan Zhang, Yan Li, Xu‐Yu Zhang   +10 more
wiley   +1 more source

A rare case of an incarcerated incisional hernia with gravid uterus

, 2022
Herniation of a gravid uterus through an abdominal wall incisional hernia with overlying skin necrosis is exceptionally rare. A 29-year-old multiparous K30 + 4/40 pregnant female presented with a 1-month history of worsening abdominal wall skin changes ...
Caleo, Pamela J, Copertino, Nicolas, Li, Damon, Chin, Xinlin   +3 more
core   +1 more source

Incisional Hernias [PDF]

Digestive Surgery, 2003
Incisional hernias represent one of the most frequent complications of abdominal surgery. The incidence is probably underestimated. The pathogenesis is complex and not fully understood, implying patient-related factors (i.e., collagen biochemistry, obesity, age) as well as technical factors, including, among others, wound infection, suture material ...
Elie Yahchouchy-Chouillard, Tamer Aura, Olivier Picone, Jean-Charles Etienne, Abe Fingerhut   +4 more
openaire   +1 more source

Essential Updates 2024–2026: Advances in Colorectal Cancer Surgery

Annals of Gastroenterological Surgery, EarlyView.
ABSTRACT Surgical innovation in colorectal cancer is increasingly judged not by technical feasibility alone, but by whether it improves oncological outcomes, preserves function, reduces morbidity, or makes difficult procedures more reproducible. This structured narrative review examines major surgical studies published from January 2024 through July ...
Hiroyasu Kagawa, Yusuke Kinugasa
wiley   +1 more source

First laparoscopic totally extraperitoneal repair of Laugier s hernia a case report

, 2013
t An atypical femoral hernia developing through the lacunar ligament is called Laugier’s hernia. Preoperative diagnosis of these atypical hernias is very diYcult because of their rarity and similar clinical appearance to conventional femoral hernias.
Işık, Burak, Köse, Evren, Yılmaz, Sezai, Ateş, Mustafa, Dirican, Abuzer   +4 more
core   +1 more source

Laparoscopic or Robotically Assisted Colectomy with a Pfannenstiel Incision Reduces the Incisional Hernia Incidence

Journal of the Anus, Rectum and Colon
Objectives: The present study examined the incidence of incisional hernia by comparing patients from whom a specimen was extracted either through a Pfannenstiel incision (PI) with an intracorporeal anastomosis or via a midline incision (MI) with an ...
Soichiro Natsume, Tatsuro Yamaguchi, Daisuke Nakano, Misato Takao, Hiroki Kato, Ichiro Ise, Sakiko Nakamori, Akira Dejima, Kazushige Kawai   +8 more
doaj   +1 more source

Long-term recurrence and complication rates after incisional hernia repair with the open onlay technique

BMC Surgery, 2009
Background Incisional hernia after abdominal surgery is a well-known complication. Controversy still exists with respect to the choice of hernia repair technique.
Gögenur Ismail, Klein Mads, Andersen Lars, Rosenberg Jacob   +3 more
doaj   +1 more source

One-year outcome after repair of giant incisional hernia using synthetic mesh or full-thickness skin graft : a randomised controlled trial

, 2019
PURPOSE: Repair of giant incisional hernia often requires complex surgery and the results of conventional methods using synthetic mesh as reinforcement are unsatisfactory, with high recurrence and complication rates.
Clay, Leonard, Gunnarsson, Ulf, Stark, B,, Gunnarsson, U, Holmdahl, Viktor, Gunnarsson, Ulf,, Clay, L, Strigard, K, Stark, Birgit,, Holmdahl, V, Clay, Leonard,, Stark, Birgit, Strigård, Karin, Holmdahl, Viktor,, Strigård, Karin,   +14 more
core   +1 more source